background

Afatinib Impurity 28

Afatinib Impurity 28 Watermark

Afatinib Impurity 28

CAT No:CL-ATB-41
CAS No:NA
Mol.F:C22H20ClFN4O4
Mol.Wt.:458.9
Rel. Cas No:
Chemical Name:1-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-2-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one
SMILES: OC1CCC(=O)N1c2cc3c(Nc4ccc(F)c(Cl)c4)ncnc3cc2O[C@H]5CCCO5
Inventory Status:Custom synthesis

This impurity is related to Afatinib Impurity 28 is provided with comprehensive characterization data in accordance with regulatory guidelines. It is suitable for use in analytical method development, method validation (AMV), Quality Control (QC) applications for Abbreviated New Drug Applications (ANDA) and commercial production of Asenapine.

Afatinib Impurity 28 is used as a reference standard in analytical research. It ensures consistency of formulations.

Chemical Name:1-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-2-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one
Country of Origin: India
Product Category: Impurity Reference Standard
API NAME: Afatinib
Molecular Formula: C22H20ClFN4O4
Molecular Weight: 458.9
Storage: Store in a cool, dry place.

Related Products

Afatinib
Cleanchem Watermark
Cat. No: CL-ATB-01
CAS No: 850140-72-6
Mol. F: C24H25ClFN5O3
Mol. Wt: 485.9
Inv. Status: Custom Synthesis
Afatinib Impurity A
Cleanchem Watermark
Cat. No: CL-ATB-02
CAS No: 402855-07-6
Mol. F: C18H14ClFN4O4
Mol. Wt: 404.8
Inv. Status: Custom Synthesis
Afatinib Impurity B
Cleanchem Watermark
Cat. No: CL-ATB-03
CAS No: 314771-76-1
Mol. F: C18H16ClFN4O2
Mol. Wt: 374.8
Inv. Status: Custom Synthesis
Afatinib Impurity C
Cleanchem Watermark
Cat. No: CL-ATB-04
CAS No: 945553-91-3
Mol. F: C24H25ClFN5O3
Mol. Wt: 486
Inv. Status: Custom Synthesis
Afatinib Impurity D
Cleanchem Watermark
Cat. No: CL-ATB-05
CAS No: 1680184-59-1
Mol. F: C24H25ClFN5O3
Mol. Wt: 485.9
Inv. Status: Custom Synthesis
Afatinib Impurity E
Cleanchem Watermark
Cat. No: CL-ATB-06
CAS No: 2223677-63-0
Mol. F: C24H25Cl2N5O3
Mol. Wt: 502.4
Inv. Status: Custom Synthesis
Afatinib Impurity F
Cleanchem Watermark
Cat. No: CL-ATB-07
CAS No: NA
Mol. F: C24H25F2N5O3
Mol. Wt: 469.5
Inv. Status: Custom Synthesis
Afatinib Impurity G
Cleanchem Watermark
Cat. No: CL-ATB-08
CAS No: NA
Mol. F: C24H25ClFN5O3
Mol. Wt: 486
Inv. Status: Custom Synthesis
Afatinib Impurity H
Cleanchem Watermark
Cat. No: CL-ATB-09
CAS No: 2223677-64-1
Mol. F: C22H20ClFN4O3
Mol. Wt: 442.9
Inv. Status: Custom Synthesis
Afatinib Impurity I
Cleanchem Watermark
Cat. No: CL-ATB-10
CAS No: NA
Mol. F: C22H19BrClFN4O3
Mol. Wt: 521.8
Inv. Status: Custom Synthesis
Afatinib Impurity J
Cleanchem Watermark
Cat. No: CL-ATB-11
CAS No: 1456696-14-2
Mol. F: C18H22N4O4
Mol. Wt: 358.4
Inv. Status: Custom Synthesis
N-Desmethyl Afatinib
Cleanchem Watermark
Cat. No: CL-ATB-12
CAS No: 2413212-13-0
Mol. F: C23H23ClFN5O3
Mol. Wt: 471.9
Inv. Status: Custom Synthesis
Afatinib N-Oxide
Cleanchem Watermark
Cat. No: CL-ATB-13
CAS No: 2413212-13-0
Mol. F: C24H25ClFN5O4
Mol. Wt: 501.9
Inv. Status: Custom Synthesis
Afatinib Impurity 2
Cleanchem Watermark
Cat. No: CL-ATB-14
CAS No: 1449430-45-8
Mol. F: C14H8ClFN4O3
Mol. Wt: 334.7
Inv. Status: Custom Synthesis
Afatinib Impurity 3
Cleanchem Watermark
Cat. No: CL-ATB-15
CAS No: 2475094-96-1
Mol. F: C14H7ClF2N4O2
Mol. Wt: 336.7
Inv. Status: Custom Synthesis
Afatinib Impurity 4
Cleanchem Watermark
Cat. No: CL-ATB-16
CAS No: 2512206-82-3
Mol. F: C14H7Cl2FN4O2
Mol. Wt: 353.1
Inv. Status: Custom Synthesis
Afatinib Impurity 5
Cleanchem Watermark
Cat. No: CL-ATB-17
CAS No: 179552-74-0
Mol. F: C15H10ClFN4O3
Mol. Wt: 348.7
Inv. Status: Custom Synthesis
Afatinib Impurity 6
Cleanchem Watermark
Cat. No: CL-ATB-18
CAS No: 2413212-07-2
Mol. F: C18H17FN4O2
Mol. Wt: 340.4
Inv. Status: Custom Synthesis
Afatinib Impurity 7
Cleanchem Watermark
Cat. No: CL-ATB-19
CAS No: 2413212-08-3
Mol. F: C18H18N4O2
Mol. Wt: 322.4
Inv. Status: Custom Synthesis
Afatinib Impurity 8
Cleanchem Watermark
Cat. No: CL-ATB-20
CAS No: 2413212-09-4
Mol. F: C18H17ClN4O2
Mol. Wt: 356.8
Inv. Status: Custom Synthesis
Afatinib Impurity 9
Cleanchem Watermark
Cat. No: CL-ATB-21
CAS No: 2413212-10-7
Mol. F: C30H36ClFN6O5
Mol. Wt: 615.1
Inv. Status: Custom Synthesis
Afatinib Impurity 10
Cleanchem Watermark
Cat. No: CL-ATB-22
CAS No: NA
Mol. F: C48H50Cl2F2N10O6
Mol. Wt: 971.9
Inv. Status: Custom Synthesis
Afatinib Impurity 11
Cleanchem Watermark
Cat. No: CL-ATB-23
CAS No: 2413212-17-4
Mol. F: C22H20ClFN4O3
Mol. Wt: 442.9
Inv. Status: Custom Synthesis
Afatinib Impurity 12
Cleanchem Watermark
Cat. No: CL-ATB-24
CAS No: 2121530-37-6
Mol. F: C22H20ClFN4O4
Mol. Wt: 458.9
Inv. Status: Custom Synthesis
Afatinib Impurity 13
Cleanchem Watermark
Cat. No: CL-ATB-25
CAS No: 2413212-19-6
Mol. F: C22H20ClFN4O4
Mol. Wt: 458.9
Inv. Status: Custom Synthesis
Afatinib Impurity 14
Cleanchem Watermark
Cat. No: CL-ATB-26
CAS No: 2413212-21-0
Mol. F: C24H27ClFN5O4
Mol. Wt: 504
Inv. Status: Custom Synthesis
Afatinib Impurity 15
Cleanchem Watermark
Cat. No: CL-ATB-27
CAS No: 2413212-23-2
Mol. F: C24H27ClFN5O4
Mol. Wt: 504
Inv. Status: Custom Synthesis
Afatinib Impurity 16
Cleanchem Watermark
Cat. No: CL-ATB-28
CAS No: 2223677-60-7
Mol. F: C19H16ClFN4O3
Mol. Wt: 402.8
Inv. Status: Custom Synthesis
Afatinib Impurity 17
Cleanchem Watermark
Cat. No: CL-ATB-29
CAS No: NA
Mol. F: C21H22ClFN5O2
Mol. Wt: 430.9
Inv. Status: Custom Synthesis
Afatinib Impurity 18
Cleanchem Watermark
Cat. No: CL-ATB-30
CAS No: 2413212-25-4
Mol. F: C24H26FN5O3
Mol. Wt: 451.5
Inv. Status: Custom Synthesis
Afatinib Impurity 19
Cleanchem Watermark
Cat. No: CL-ATB-31
CAS No: 1245555-42-3
Mol. F: C21H21ClFN5O2
Mol. Wt: 429.9
Inv. Status: Custom Synthesis
Afatinib Impurity 20
Cleanchem Watermark
Cat. No: CL-ATB-32
CAS No: 2085843-51-0
Mol. F: C22H23ClFN5O2
Mol. Wt: 443.9
Inv. Status: Custom Synthesis
Afatinib Impurity 21
Cleanchem Watermark
Cat. No: CL-ATB-33
CAS No: 2044709-72-8
Mol. F: C18H16F2N4O2
Mol. Wt: 358.4
Inv. Status: Custom Synthesis
Afatinib Impurity 22
Cleanchem Watermark
Cat. No: CL-ATB-34
CAS No: NA
Mol. F: C28H29ClFN5O7
Mol. Wt: 601.1
Inv. Status: Custom Synthesis
Afatinib Dimaleate
Cleanchem Watermark
Cat. No: CL-ATB-35
CAS No: 850140-73-7
Mol. F: C24H25ClFN5O3 : 2(C4H4O4)
Mol. Wt: 485.9 : 2(116.1)
Inv. Status: Custom Synthesis
Afatinib Impurity 23
Cleanchem Watermark
Cat. No: CL-ATB-36
CAS No: 2223677-58-3
Mol. F: C22H20ClFN4O4
Mol. Wt: 458.9
Inv. Status: Custom Synthesis
N-Nitroso Afatinib
Cleanchem Watermark
Cat. No: CL-ATB-NO-01
CAS No: NA
Mol. F: C24H24ClFN6O4
Mol. Wt: 514.94
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity A
Cleanchem Watermark
Cat. No: CL-ATB-NO-03
CAS No: NA
Mol. F: C18H13ClFN5O5
Mol. Wt: 433.78
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity B
Cleanchem Watermark
Cat. No: CL-ATB-NO-04
CAS No: NA
Mol. F: C18H15ClFN5O3
Mol. Wt: 403.8
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity C
Cleanchem Watermark
Cat. No: CL-ATB-NO-05
CAS No: NA
Mol. F: C24H24ClFN6O4
Mol. Wt: 514.94
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity D
Cleanchem Watermark
Cat. No: CL-ATB-NO-07
CAS No: NA
Mol. F: C23H22ClFN6O4
Mol. Wt: 500.92
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity E
Cleanchem Watermark
Cat. No: CL-ATB-NO-10
CAS No: NA
Mol. F: C23H22Cl2N6O4
Mol. Wt: 517.37
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity F
Cleanchem Watermark
Cat. No: CL-ATB-NO-12
CAS No: NA
Mol. F: C23H22F2N6O4
Mol. Wt: 484.46
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity G
Cleanchem Watermark
Cat. No: CL-ATB-NO-14
CAS No: NA
Mol. F: C23H22ClFN6O4
Mol. Wt: 500.92
Inv. Status: In Stock
N-Nitroso Afatinib Impurity J
Cleanchem Watermark
Cat. No: CL-ATB-NO-17
CAS No: NA
Mol. F: C17H19N5O5
Mol. Wt: 373.37
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity 1
Cleanchem Watermark
Cat. No: CL-ATB-NO-25
CAS No: NA
Mol. F: C29H33ClFN7O6
Mol. Wt: 630.07
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity 2
Cleanchem Watermark
Cat. No: CL-ATB-NO-26
CAS No: NA
Mol. F: C47H47Cl2F2N11O7
Mol. Wt: 986.86
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity 3
Cleanchem Watermark
Cat. No: CL-ATB-NO-27
CAS No: NA
Mol. F: C23H23FN6O4
Mol. Wt: 466.47
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity 4
Cleanchem Watermark
Cat. No: CL-ATB-NO-28
CAS No: NA
Mol. F: C20H18ClFN6O3
Mol. Wt: 444.85
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity 5
Cleanchem Watermark
Cat. No: CL-ATB-NO-29
CAS No: NA
Mol. F: C21H20ClFN6O3
Mol. Wt: 458.88
Inv. Status: Custom Synthesis
N-Nitroso Afatinib Impurity 6
Cleanchem Watermark
Cat. No: CL-ATB-NO-30
CAS No: NA
Mol. F: C27H26ClFN6O8
Mol. Wt: 616.99
Inv. Status: Custom Synthesis
Afatinib Impurity 24
Cleanchem Watermark
Cat. No: CL-ATB-37
CAS No: 1255078-56-8
Mol. F: C8H15NO2 : HCl
Mol. Wt: 157.2 : 36.5
Inv. Status: Custom Synthesis
Afatinib Impurity 25
Cleanchem Watermark
Cat. No: CL-ATB-38
CAS No: 212776-19-7
Mol. F: C7H13NO2
Mol. Wt: 143.2
Inv. Status: Custom Synthesis
Afatinib Impurity 26
Cleanchem Watermark
Cat. No: CL-ATB-39
CAS No: 314771-88-5
Mol. F: C18H14ClFN4O4
Mol. Wt: 404.8
Inv. Status: Custom Synthesis
Afatinib Impurity 27
Cleanchem Watermark
Cat. No: CL-ATB-40
CAS No: 618061-76-0
Mol. F: C24H27ClFN4O6P
Mol. Wt: 552.9
Inv. Status: Custom Synthesis
Afatinib Impurity 29
Cleanchem Watermark
Cat. No: CL-ATB-42
CAS No: NA
Mol. F: C22H23ClFN4O6P
Mol. Wt: 524.9
Inv. Status: Custom Synthesis
Afatinib Impurity 32
Cleanchem Watermark
Cat. No: CL-ATB-43
CAS No: 2323570-72-3
Mol. F: C24H27ClFN5O4
Mol. Wt: 504
Inv. Status: Custom Synthesis
Afatinib Impurity 33
Cleanchem Watermark
Cat. No: CL-ATB-44
CAS No: 162012-69-3
Mol. F: C8H4FN3O3
Mol. Wt: 209.1
Inv. Status: Custom Synthesis
Afatinib Impurity 34
Cleanchem Watermark
Cat. No: CL-ATB-45
CAS No: 16499-57-3
Mol. F: C8H5FN2O
Mol. Wt: 164.1
Inv. Status: Custom Synthesis
Afatinib Impurity 35
Cleanchem Watermark
Cat. No: CL-ATB-46
CAS No: NA
Mol. F: C14H7F3N4O2 : HCl
Mol. Wt: 320.2 : 36.5
Inv. Status: Custom Synthesis
Afatinib Impurity 36
Cleanchem Watermark
Cat. No: CL-ATB-47
CAS No: 2044709-79-5
Mol. F: C18H16Cl2N4O2
Mol. Wt: 391.3
Inv. Status: Custom Synthesis
Afatinib Impurity 37
Cleanchem Watermark
Cat. No: CL-ATB-48
CAS No: 2223677-61-8
Mol. F: C20H19ClFN5O2
Mol. Wt: 415.9
Inv. Status: Custom Synthesis
Afatinib Impurity 38
Cleanchem Watermark
Cat. No: CL-ATB-49
CAS No: 2223677-65-2
Mol. F: C38H30Cl2F2N8O6
Mol. Wt: 803.6
Inv. Status: Custom Synthesis
Afatinib Impurity 39
Cleanchem Watermark
Cat. No: CL-ATB-50
CAS No: 2223677-66-3
Mol. F: C22H21ClFN5O4
Mol. Wt: 473.9
Inv. Status: Custom Synthesis
Afatinib Impurity 40
Cleanchem Watermark
Cat. No: CL-ATB-51
CAS No: NA
Mol. F: C20H18ClFN4O3
Mol. Wt: 416.8
Inv. Status: Custom Synthesis
Afatinib Impurity 41
Cleanchem Watermark
Cat. No: CL-ATB-52
CAS No: 2475095-50-0
Mol. F: C14H7ClF2N4O2
Mol. Wt: 336.7
Inv. Status: Custom Synthesis
Afatinib Impurity 42
Cleanchem Watermark
Cat. No: CL-ATB-53
CAS No: 2413212-27-6
Mol. F: C27H27ClFN5O7
Mol. Wt: 588
Inv. Status: Custom Synthesis
Afatinib Impurity 43
Cleanchem Watermark
Cat. No: CL-ATB-54
CAS No: 402855-03-2
Mol. F: C18H16ClFN4O2
Mol. Wt: 374.8
Inv. Status: Custom Synthesis
Afatinib Bis-dimethylamino Impurity
Cleanchem Watermark
Cat. No: CL-ATB-55
CAS No: 2414260-31-2
Mol. F: C26H32ClFN6O3
Mol. Wt: 531
Inv. Status: Custom Synthesis
Afatinib Butoxy Analog
Cleanchem Watermark
Cat. No: CL-ATB-56
CAS No: NA
Mol. F: C24H27ClFN5O2
Mol. Wt: 472
Inv. Status: Custom Synthesis
Afatinib Sulfonic Acid Analog
Cleanchem Watermark
Cat. No: CL-ATB-57
CAS No: 2283295-16-7
Mol. F: C24H27ClFN5O6S
Mol. Wt: 568
Inv. Status: Custom Synthesis
Afatinib D4
Cleanchem Watermark
Cat. No: CL-ATB-58
CAS No: NA
Mol. F: C24H21D4ClFN5O3
Mol. Wt: 490
Inv. Status: Custom Synthesis
Afatinib D6
Cleanchem Watermark
Cat. No: CL-ATB-59
CAS No: 1313874-96-2
Mol. F: C24H19D6ClFN5O3
Mol. Wt: 492
Inv. Status: Custom Synthesis
Afatinib 13C6
Cleanchem Watermark
Cat. No: CL-ATB-60
CAS No: NA
Mol. F: C1813C6H25ClFN5O3
Mol. Wt: 491.9
Inv. Status: Custom Synthesis
Document