Clotiazepam Products | Cleanchem - Clotiazepam is a benzodiazepine used to treat anxiety, agitation, and stress-related disorders. It works by enhancing the activity of the neurotransmitter GABA, which helps to calm the nervous system and reduce anxiety. Clotiazepam is commonly prescribed for short-term use to avoid dependency. Potential side effects include drowsiness, dizziness, and an increased risk of falls, especially in older adults.