Atripla Products | Cleanchem - Atripla is a fixed-dose combination of efavirenz, emtricitabine, and tenofovir disoproxil fumarate used in the treatment of HIV-1 infection. It simplifies therapy by combining three antiretrovirals into a single once-daily tablet. It works by inhibiting reverse transcriptase, preventing viral replication. Common side effects include dizziness, rash, and kidney issues with long-term use.