Ceftobiprole Products | Cleanchem - Ceftobiprole is a fifth-generation cephalosporin with broad-spectrum activity, including effectiveness against MRSA and Enterococcus faecalis. It is used for treating complicated skin infections and hospital-acquired pneumonia (excluding ventilator-associated cases). It is administered intravenously and has good tissue distribution. Its dual Gram-positive and Gram-negative activity makes it valuable in resistant infections.