Grapiprant Products | Cleanchem - Grapiprant is a non-steroidal anti-inflammatory drug (NSAID) primarily used in veterinary medicine to treat pain and inflammation associated with osteoarthritis in dogs. It works by blocking the EP4 receptor, one of the key mediators of pain and inflammation triggered by prostaglandin E2. Its selective action helps reduce discomfort without significantly affecting gastrointestinal or kidney functions.