Hesperidin Products | Cleanchem - Hesperidin is a flavonoid glycoside found in citrus fruits. It has been shown to have antioxidant, anti-inflammatory, and vascular protective effects. Hesperidin is often used as a supplement for improving circulation and reducing the symptoms of varicose veins, hemorrhoids, and other circulatory conditions. It works by strengthening blood vessels and improving blood flow, which helps reduce swelling and promote overall vascular health.