Vorapaxar Products | Cleanchem - Vorapaxar is an antiplatelet medication used to reduce the risk of thrombotic cardiovascular events in patients with a history of heart attack or peripheral artery disease. It works by antagonizing the protease-activated receptor-1 (PAR-1) on platelets, thereby inhibiting thrombin-induced platelet aggregation. This makes blood less likely to form clots that could lead to strokes or heart attacks. It is typically used in combination with other antiplatelet agents.