Vorinostat Products | Cleanchem - Vorinostat is a histone deacetylase (HDAC) inhibitor used primarily in the treatment of cutaneous T-cell lymphoma (CTCL). It modifies the expression of genes involved in cell cycle regulation, apoptosis, and differentiation by altering chromatin structure. Vorinostat represents one of the first epigenetic therapies approved for cancer. It is being studied for potential use in other malignancies and neurodegenerative diseases.