Acemetacin Products | Cleanchem - Acemetacin is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, and other musculoskeletal disorders. It reduces inflammation and pain by inhibiting cyclooxygenase (COX) enzymes, thereby decreasing prostaglandin production. It is a prodrug of indometacin, offering similar benefits with potentially improved gastrointestinal tolerance. Acemetacin is generally used in short-term therapy.