Atipamezole Products | Cleanchem - Atipamezole is a selective alpha-2 adrenergic antagonist used primarily in veterinary medicine. It is most commonly used as a reversal agent for the sedative and anesthetic effects of alpha-2 agonists like medetomidine or dexmedetomidine. By antagonizing alpha-2 receptors, it helps to quickly reverse sedation and restore normal physiological functions in animals.