Cefpirome Products | Cleanchem - Cefpirome sulfate is a fourth-generation cephalosporin with broad-spectrum activity against both Gram-positive and Gram-negative bacteria. It is effective in treating nosocomial infections, septicemia, and lower respiratory tract infections. It is resistant to many beta-lactamases and is administered via injection. Common side effects include gastrointestinal upset and local irritation at the injection site.