Cefuroxime Products | Cleanchem - Cefuroxime is a second-generation cephalosporin used to treat respiratory tract infections, urinary tract infections, and skin infections. It can be administered orally as cefuroxime axetil or intravenously. It is stable to some beta-lactamases and effective against both Gram-positive and Gram-negative organisms. Side effects may include gastrointestinal upset and rash.