Chlorambucil Products | Cleanchem - Chlorambucil is an alkylating agent used primarily in the treatment of chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma. It works by interfering with DNA replication, leading to cell death. Chlorambucil is typically used in the management of hematological cancers, especially in older patients or those who cannot tolerate more aggressive therapies. Side effects include bone marrow suppression, nausea, and hair loss.