Cisapride Products | Cleanchem - Cisapride is a prokinetic agent used to treat gastrointestinal motility disorders, including gastroesophageal reflux disease (GERD) and chronic constipation. It works by enhancing the release of acetylcholine, which increases peristalsis and speeds up gastric emptying. However, due to its potential for causing serious cardiac arrhythmias, cisapride has been largely withdrawn from the market in many countries. Side effects may include abdominal cramps, diarrhea, and heart issues like arrhythmia.