Clomiphene Products | Cleanchem - Clomiphene is a selective estrogen receptor modulator (SERM) primarily used to treat infertility in women by inducing ovulation. It works by blocking estrogen receptors in the hypothalamus, increasing the release of gonadotropins (LH and FSH), which stimulate ovary function. Clomiphene is commonly prescribed for women with polycystic ovary syndrome (PCOS). Side effects can include hot flashes, abdominal discomfort, and multiple pregnancies.