Clonixin Products | Cleanchem - Clonixin is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation associated with conditions like arthritis and musculoskeletal pain. It works by inhibiting cyclooxygenase (COX), an enzyme involved in the production of prostaglandins, which mediate pain and inflammation. Clonixin is often used for short-term pain management. Side effects include gastrointestinal discomfort, headache, and dizziness.