Colchicine Products | Cleanchem - Colchicine is used to treat gout attacks and familial Mediterranean fever by reducing inflammation. It works by inhibiting microtubule polymerization, thus preventing the migration of inflammatory cells to affected areas. Colchicine is typically used for short-term relief during flare-ups of gout and can also be used for preventing gout attacks. Side effects include gastrointestinal upset, including diarrhea and nausea.