Cyclamate Products | Cleanchem - Cyclamate is an artificial sweetener used as a sugar substitute in low-calorie and sugar-free foods and beverages. It is approximately 30?0 times sweeter than sucrose but is not metabolized for energy. Though widely used in some countries, it was banned in the U.S. due to concerns over its potential carcinogenicity in early studies. Later reviews have questioned these findings, and it's considered safe in many regions.