Cyclopentolate Products | Cleanchem - Cyclopentolate is an anticholinergic drug used in ophthalmology to dilate the pupil (mydriasis) and paralyze accommodation (cycloplegia) for diagnostic eye exams. It blocks muscarinic receptors in the eye, relaxing the ciliary muscle. Effects begin within 30?0 minutes and last several hours. Side effects may include blurred vision, photophobia, and in rare cases, systemic anticholinergic effects.