Levobunolol Products | Cleanchem - Levobunolol is a non-selective beta-blocker used topically in the treatment of elevated intraocular pressure in glaucoma. It decreases aqueous humor production, thereby lowering intraocular pressure. Levobunolol is applied as eye drops and may cause local irritation or systemic beta-blocker effects like bradycardia in sensitive individuals. It is effective with once- or twice-daily dosing.