Rosuvastatin Products | Cleanchem - Rosuvastatin is a statin drug used to lower cholesterol and reduce the risk of heart disease. It works by inhibiting HMG-CoA reductase, an enzyme responsible for cholesterol production in the liver. By lowering low-density lipoprotein (LDL) cholesterol and increasing high-density lipoprotein (HDL) cholesterol, rosuvastatin helps prevent cardiovascular events like heart attacks and strokes.