Vinflunine Products | Cleanchem - Vinflunine is a semi-synthetic vinca alkaloid used in the treatment of advanced or metastatic transitional cell carcinoma of the urothelium (a type of bladder cancer). It disrupts microtubule dynamics, leading to inhibition of mitosis and cancer cell death. Vinflunine is structurally modified to improve efficacy and reduce toxicity compared to earlier vinca alkaloids. It is generally used when other treatments have failed.