Voclosporin Products | Cleanchem - Voclosporin is an immunosuppressive agent used in the treatment of lupus nephritis, a serious kidney complication of systemic lupus erythematosus. It is a calcineurin inhibitor, similar to cyclosporine, but with improved potency and safety profile. By suppressing T-cell activation, it reduces immune-mediated damage to the kidneys. Voclosporin was approved for use in the U.S. in 2021.