Xipamide Products | Cleanchem - Xipamide is a diuretic used in the treatment of high blood pressure and edema (fluid retention). As a thiazide-like diuretic, it promotes the excretion of sodium and water from the body, which helps reduce blood volume and lower blood pressure. Xipamide is often prescribed to manage conditions such as hypertension, heart failure, or kidney disease. It works by inhibiting sodium reabsorption in the kidneys, leading to increased urine production.