N-Nitroso Cabazitaxel Impurity 1

Chemical Name: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-11-hydroxy-9-(((2R,3S)-2-hydroxy-3-(methyl(nitroso)amino)-3-phenylpropanoyl)oxy)-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate.

Country of Origin: India

Product Category: Cabazitaxel Impurities

N-Nitroso Cabazitaxel Impurity 1 is identified by CAS No. NA and is chemically known as (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-11-hydroxy-9-(((2R,3S)-2-hydroxy-3-(methyl(nitroso)amino)-3-phenylpropanoyl)oxy)-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate.

N-Nitroso Cabazitaxel Impurity 1 is provided with comprehensive characterization data in accordance with regulatory guidelines. It is suitable for use in analytical method development, method validation (AMV), Quality Control (QC) applications for Abbreviated New Drug Applications (ANDA) and commercial production of Cabazitaxel.

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