Impurity Reference Standard - Products

Binimetinib

CAT No: CL-BNM-01 CAS No: 606143-89-9 Mol Wt: 441.2 Mol F: C17H15BrF2N4O3 Inv Status: Custom Synthesis

Chemical Name: 5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzo[d]imidazole-6-carboxamide

Binimetinib Impurity 1

CAT No: CL-BNM-02 CAS No: 284030-58-6 Mol Wt: 232.1 Mol F: C8H6F2N2O4 Inv Status: Custom Synthesis

Chemical Name: Methyl 4-amino-2,3-difluoro-5-nitrobenzoate

Binimetinib Impurity 2

CAT No: CL-BNM-03 CAS No: 391212-29-6 Mol Wt: 103.1 Mol F: C4H9NO2 Inv Status: Custom Synthesis

Chemical Name: O-(2-(Vinyloxy)ethyl)hydroxylamine

Binimetinib Isomer

CAT No: CL-BNM-04 CAS No: NA Mol Wt: 441.2 Mol F: C17H15BrF2N4O3 Inv Status: Custom Synthesis

Chemical Name: 6-[(4-Bromo-2-fluorophenyl)amino]-7-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-5-carboxamide

Binimetinib Cyclized Impurity

CAT No: CL-BNM-05 CAS No: NA Mol Wt: 513.3 Mol F: C21H23BrF2N4O4 Inv Status: Custom Synthesis

Chemical Name: 5-((4-Bromo-2-fluorophenyl)amino)-N-(2-(1-ethoxyethoxy)ethoxy)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide

Binimetinib Methyl Ester Impurity

CAT No: CL-BNM-06 CAS No: 1415559-93-1 Mol Wt: 396.2 Mol F: C16H12BrF2N3O2 Inv Status: Custom Synthesis

Chemical Name: Methyl 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate

Binimetinib Desbromo Acid Impurity

CAT No: CL-BNM-07 CAS No: 2649854-87-3 Mol Wt: 303.3 Mol F: C15H11F2N3O2 Inv Status: Custom Synthesis

Chemical Name: 4-Fluoro-5-((2-fluorophenyl)amino)-1-methyl-1H-benzo[d]imidazole-6-carboxylic acid

Binimetinib Desbromo Impurity

CAT No: CL-BNM-08 CAS No: NA Mol Wt: 362.3 Mol F: C17H16F2N4O3 Inv Status: Custom Synthesis

Chemical Name: 4-Fluoro-5-((2-fluorophenyl)amino)-N-(2-hydroxyethoxy)-1-methyl-1H-benzo[d]imidazole-6-carboxamide

N-Desmethyl Binimetinib

CAT No: CL-BNM-09 CAS No: NA Mol Wt: 427.2 Mol F: C16H13BrF2N4O3 Inv Status: Custom Synthesis

Chemical Name: 5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1H-benzo[d]imidazole-6-carboxamide

Binimetinib Impurity 3

CAT No: CL-BNM-10 CAS No: 132920-93-5 Mol Wt: 221.1 Mol F: C7H2F3NO4 Inv Status: Custom Synthesis

Chemical Name: 2,3,4-Trifluoro-6-nitrobenzoic acid

Binimetinib Impurity 4

CAT No: CL-BNM-11 CAS No: NA Mol Wt: 218.1 Mol F: C7H4F2N2O4 Inv Status: Custom Synthesis

Chemical Name: 3-Amino-2,4-difluoro-6-nitrobenzoic acid

Binimetinib Impurity 5

CAT No: CL-BNM-12 CAS No: NA Mol Wt: 760.3 Mol F: C30H20Br2F4N8O2 Inv Status: Custom Synthesis

Chemical Name: 5-((4-Bromo-2-fluorophenyl)amino)-N'-(5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carbonyl)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carbohydrazide

Binimetinib Impurity 6

CAT No: CL-BNM-13 CAS No: NA Mol Wt: 456.2 Mol F: C17H16BrF2N5O3 Inv Status: Custom Synthesis

Chemical Name: N-(2-(Aminooxy)ethoxy)-5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide

Binimetinib Impurity 7

CAT No: CL-BNM-14 CAS No: NA Mol Wt: 820.4 Mol F: C32H24Br2F4N8O4 Inv Status: Custom Synthesis

Chemical Name: N,N'-(Ethane-1,2-diylbis(oxy))bis(5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide)

Binimetinib Impurity 8

CAT No: CL-BNM-15 CAS No: NA Mol Wt: 527.3 Mol F: C23H13BrF2N4O4 Inv Status: Custom Synthesis

Chemical Name: 1,3-Dioxoisoindolin-2-yl 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate

Binimetinib Impurity 9

CAT No: CL-BNM-16 CAS No: NA Mol Wt: 380.1 Mol F: C15H8BrF2N3O2 Inv Status: Custom Synthesis

Chemical Name: 1-(4-Bromo-2-fluorophenyl)-8-fluoro-5-methyl-1,5-dihydro-3H-imidazo[4',5':4,5]benzo[1,2-c]isoxazol-3-one

Binimetinib Impurity 10

CAT No: CL-BNM-17 CAS No: 2509103-99-3 Mol Wt: 410.2 Mol F: C17H14BrF2N3O2 Inv Status: Custom Synthesis

Chemical Name: Ethyl 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate

Binimetinib Impurity 11

CAT No: CL-BNM-18 CAS No: 391212-30-9 Mol Wt: 233.2 Mol F: C12H11NO4 Inv Status: Custom Synthesis

Chemical Name: 2-(2-(Vinyloxy)ethoxy)isoindoline-1,3-dione

Binimetinib Impurity 12

CAT No: CL-BNM-19 CAS No: NA Mol Wt: 617.4 Mol F: C23H23BrF2N4O9 Inv Status: Custom Synthesis

Chemical Name: (2S,3S,4S,5R,6R)-6-(2-((5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamido)oxy)ethoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

Binimetinib Impurity 13

CAT No: CL-BNM-20 CAS No: NA Mol Wt: 614.2 Mol F: C23H17Br2F3N4O3 Inv Status: Custom Synthesis

Chemical Name: 5-(Bis(4-bromo-2-fluorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzo[d]imidazole-6-carboxamide

Binimetinib Impurity 14

CAT No: CL-BNM-21 CAS No: 326-66-9 Mol Wt: 232.1 Mol F: C8H7BrFNO Inv Status: Custom Synthesis

Chemical Name: N-(4-Bromo-2-fluorophenyl)acetamide

Binimetinib Impurity 15

CAT No: CL-BNM-22 CAS No: 2851526-50-4 Mol Wt: 381.2 Mol F: C15H11BrF2N4O Inv Status: Custom Synthesis

Chemical Name: 5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide

Binimetinib Impurity 18

CAT No: CL-BNM-23 CAS No: 918321-31-0 Mol Wt: 215.1 Mol F: C7H6FN3O4 Inv Status: Custom Synthesis

Chemical Name: 2,4-Diamino-3-fluoro-5-nitrobenzoic acid

Binimetinib Impurity 19

CAT No: CL-BNM-24 CAS No: 284030-57-5 Mol Wt: 218.1 Mol F: C7H4F2N2O4 Inv Status: Custom Synthesis

Chemical Name: 4-Amino-2,3-difluoro-5-nitrobenzoic acid

Binimetinib Impurity 20

CAT No: CL-BNM-25 CAS No: NA Mol Wt: 397.2 Mol F: C15H11BrF2N4O2 Inv Status: Custom Synthesis

Chemical Name: 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-N-hydroxy-1-methyl-1H-benzo[d]imidazole-6-carboxamide

Binimetinib D3

CAT No: CL-BNM-26 CAS No: NA Mol Wt: 444.3 Mol F: C17H12D3BrF2N4O3 Inv Status: Custom Synthesis

Chemical Name: 5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1-(methyl-d3)-1H-benzo[d]imidazole-6-carboxamide

Binimetinib 13C,D3

CAT No: CL-BNM-27 CAS No: NA Mol Wt: 445.2 Mol F: C1613CH12D3BrF2N4O3 Inv Status: Custom Synthesis

Chemical Name: 5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1-(methyl-13C-d3)-1H-benzo[d]imidazole-6-carboxamide

Binimetinib Acid Impurity

CAT No: CL-BNM-28 CAS No: 1415564-99-6 Mol Wt: 382.2 Mol F: C15H10BrF2N3O2 Inv Status: Custom Synthesis

Chemical Name: 5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylic acid

Binimetinib Amide Impurity

CAT No: CL-BNM-29 CAS No: 1604812-70-5 Mol Wt: 497.3 Mol F: C21H23BrF2N4O3 Inv Status: Custom Synthesis

Chemical Name: 5-((4-Bromo-2-fluorophenyl)amino)-N-(2-(tert-butoxy)ethoxy)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide

Binimetinib Desbromo Vinyloxy Impurity

CAT No: CL-BNM-30 CAS No: 2649854-88-4 Mol Wt: 388.4 Mol F: C19H18F2N4O3 Inv Status: Custom Synthesis

Chemical Name: 4-Fluoro-5-((2-fluorophenyl)amino)-1-methyl-N-(2-(vinyloxy)ethoxy)-1H-benzo[d]imidazole-6-carboxamide

Binimetinib Ethyl Ether Impurity

CAT No: CL-BNM-31 CAS No: NA Mol Wt: 469.3 Mol F: C19H19BrF2N4O3 Inv Status: Custom Synthesis

Chemical Name: 5-((4-Bromo-2-fluorophenyl)amino)-N-(2-ethoxyethoxy)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide

Type:Impurity Reference Standard

API NAME:Binimetinib

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