Impurity Reference Standard - Products

Bortezomib ((1R,2S)-Bortezomib)

CAT No: CL-BTZ-01 CAS No: 179324-69-7 Mol Wt: 384.2 Mol F: C19H25BN4O4 Inv Status: Custom Synthesis

Chemical Name: Bortezomib ((1R,2S)-Bortezomib)

Bortezomib Impurity (R,R-Isomer)

CAT No: CL-BTZ-02 CAS No: 1132709-15-9 Mol Wt: 384.2 Mol F: C19H25BN4O4 Inv Status: Custom Synthesis

Chemical Name: ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid

Bortezomib Impurity (1S,2R - Isomer)

CAT No: CL-BTZ-03 CAS No: 1132709-16-0 Mol Wt: 384.3 Mol F: C19H25BN4O4 Inv Status: Custom Synthesis

Chemical Name: [(1S)-3-Methyl-1-({(2R)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl} amino)butyl]boronic Acid

Bortezomib Impurity (S,S-Isomer)

CAT No: CL-BTZ-04 CAS No: 1132709-14-8 Mol Wt: 384.2 Mol F: C19H25BN4O4 Inv Status: Custom Synthesis

Chemical Name: ((S)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid

Bortezomib Impurity 2 (RR-Isomer)

CAT No: CL-BTZ-06 CAS No: NA Mol Wt: 356.4 Mol F: C19H24N4O3 Inv Status: Custom Synthesis

Chemical Name: N-((R)-1-(((R)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 2 (Mixture Of (1S,2R)-Isomer And (1R,2R)-Isomer)

CAT No: CL-BTZ-07 CAS No: 2747958-64-9 Mol Wt: 356.4 Mol F: C19H24N4O3 Inv Status: Custom Synthesis

Chemical Name: N-(1-(((R)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 3

CAT No: CL-BTZ-08 CAS No: 2748159-75-1 Mol Wt: 270.3 Mol F: C14H14N4O2 Inv Status: Custom Synthesis

Chemical Name: N-(1-carbamoyl-2-phenylethyl)pyrazine-2-carboxamide

Bortezomib Impurity 4

CAT No: CL-BTZ-09 CAS No: 862894-96-0 Mol Wt: 354.4 Mol F: C19H22N4O3 Inv Status: Custom Synthesis

Chemical Name: (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 5

CAT No: CL-BTZ-10 CAS No: 2379402-85-2 Mol Wt: 370.4 Mol F: C19H22N4O4 Inv Status: Custom Synthesis

Chemical Name: (S)-N-(1-(3-hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 6

CAT No: CL-BTZ-11 CAS No: NA Mol Wt: 400.3 Mol F: C19H25BN4O5 Inv Status: Custom Synthesis

Chemical Name: ((R)-3-Hydroxy-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid

Bortezomib Impurity 7

CAT No: CL-BTZ-12 CAS No: NA Mol Wt: 237.1 Mol F: C10H16BN3O3 Inv Status: Custom Synthesis

Chemical Name: (R)-(3-Methyl-1-(pyrazine-2-carboxamido)butyl)boronic acid

Bortezomib Impurity 8

CAT No: CL-BTZ-13 CAS No: NA Mol Wt: 490.3 Mol F: C24H27BN6O5 Inv Status: Custom Synthesis

Chemical Name: ((R)-3-Methyl-1-((S)-3-phenyl-2-(N-(pyrazine-2-carbonyl)pyrazine-2-carboxamido)propanamido)butyl)boronic acid

Bortezomib Impurity 9

CAT No: CL-BTZ-14 CAS No: 1194235-41-0 Mol Wt: 531.4 Mol F: C28H34BN5O5 Inv Status: Custom Synthesis

Chemical Name: ((R)-3-Methyl-1-((S)-3-phenyl-2-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic acid

Bortezomib Impurity 10

CAT No: CL-BTZ-15 CAS No: 390800-88-1 Mol Wt: 1098.7 Mol F: C57H69B3N12O9 Inv Status: Custom Synthesis

Chemical Name: (2S,2`S)-2,2`,2``-(((1R,1'R)-(1,3,5,2,4,6-Trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(3-phenyl-N-(pyrazine-2-carbonyl)propanamide)

Bortezomib Impurity 11

CAT No: CL-BTZ-16 CAS No: 862895-00-9 Mol Wt: 338.4 Mol F: C19H22N4O2 Inv Status: Custom Synthesis

Chemical Name: (S,E)-N-(1-((3-Methylbut-1-en-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 14

CAT No: CL-BTZ-17 CAS No: 205393-22-2 Mol Wt: 518.5 Mol F: C29H39BN4O4 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((R)-3-Methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 17

CAT No: CL-BTZ-20 CAS No: NA Mol Wt: 400.3 Mol F: C19H25BN4O5 Inv Status: Custom Synthesis

Chemical Name: ((S)-3-Hydroxy-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid

Bortezomib Impurity 18

CAT No: CL-BTZ-21 CAS No: NA Mol Wt: 710.8 Mol F: C38H46N8O6 Inv Status: Custom Synthesis

Chemical Name: N,N'-((2S,2'S)-(((1R,1'R)-Peroxybis(3-methylbutane-1,1-diyl))bis(azanediyl))bis(1-oxo-3-phenylpropane-1,2-diyl))bis(pyrazine-2-carboxamide)

Bortezomib Impurity 20

CAT No: CL-BTZ-23 CAS No: 89618-77-9 Mol Wt: 270.6 Mol F: C14H24BClO2 Inv Status: Custom Synthesis

Chemical Name: (3aS,4S,6S,7aR)-2-((S)-1-Chloro-2-methylpropyl)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole

Bortezomib Impurity 21

CAT No: CL-BTZ-24 CAS No: 94242-79-2 Mol Wt: 395.6 Mol F: C20H42BNO2Si2 Inv Status: Custom Synthesis

Chemical Name: 1, 1, 1-Trimethyl-N-((R)-2-methyl-1-((3aS, 4S, 6S, 7aR)-3a, 5, 5-trimethylhexahydro-4, 6-methanobenzo[d][1, 3, 2]dioxaborol-2-yl)propyl)-N-(trimethylsilyl)silanamine

Bortezomib Impurity 22

CAT No: CL-BTZ-25 CAS No: 94242-81-6 Mol Wt: 251.2 : 114.0 Mol F: C14H26BNO2 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (R)-2-methyl-1-((3aS, 4S, 6S, 7aR)-3a, 5, 5-trimethylhexahydro-4, 6-methanobenzo[d][1, 3, 2]dioxaborol-2-yl)propan-1-amine 2, 2, 2-trifluoroacetate

Bortezomib Impurity 23

CAT No: CL-BTZ-26 CAS No: NA Mol Wt: 270.6 Mol F: C14H24BClO2 Inv Status: Custom Synthesis

Chemical Name: (3aR,4R,6R,7aS)-2-((R)-1-Chloro-2-methylpropyl)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole

Bortezomib Impurity 24

CAT No: CL-BTZ-27 CAS No: NA Mol Wt: 395.6 Mol F: C20H42BNO2Si2 Inv Status: Custom Synthesis

Chemical Name: 1, 1, 1-trimethyl-N-((S)-2-methyl-1-((3aS, 4S, 6S, 7aR)-3a, 5, 5-trimethylhexahydro-4, 6-methanobenzo[d][1, 3, 2]dioxaborol-2-yl)propyl)-N-(trimethylsilyl)silanamine

Bortezomib Impurity 25

CAT No: CL-BTZ-28 CAS No: NA Mol Wt: 251.2 Mol F: C14H26BNO2 Inv Status: Custom Synthesis

Chemical Name: (S)-2-Methyl-1-((3aS, 4S, 6S, 7aR)-3a, 5, 5-trimethylhexahydro-4, 6-methanobenzo[d][1, 3, 2]dioxaborol-2-yl)propan-1-amine

Bortezomib Impurity 26

CAT No: CL-BTZ-29 CAS No: 78-77-3 Mol Wt: 137 Mol F: C4H9Br Inv Status: Custom Synthesis

Chemical Name: 1-Bromo-2-methylpropane

Bortezomib Impurity 27

CAT No: CL-BTZ-30 CAS No: 63-91-2 Mol Wt: 165.2 Mol F: C9H11NO2 Inv Status: Custom Synthesis

Chemical Name: L-Phenylalanine

Bortezomib Impurity 28

CAT No: CL-BTZ-31 CAS No: 18942-49-9 Mol Wt: 265.3 Mol F: C14H19NO4 Inv Status: Custom Synthesis

Chemical Name: (Tert-butoxycarbonyl)-D-phenylalanine

Bortezomib Impurity 29

CAT No: CL-BTZ-32 CAS No: 89-01-0 Mol Wt: 168.1 Mol F: C6H4N2O4 Inv Status: Custom Synthesis

Chemical Name: Pyrazine-2,3-dicarboxylic acid

Bortezomib Impurity 30

CAT No: CL-BTZ-33 CAS No: 513-36-0 Mol Wt: 92.6 Mol F: C4H9Cl Inv Status: Custom Synthesis

Chemical Name: 1-Chloro-2-methylpropane

Bortezomib Impurity 31

CAT No: CL-BTZ-34 CAS No: 84110-40-7 Mol Wt: 101.9 Mol F: C4H11BO2 Inv Status: In Stock

Chemical Name: 2-Methylpropylboronic Acid

Bortezomib Impurity 32

CAT No: CL-BTZ-35 CAS No: 2363753-29-9 Mol Wt: 265.2 : 114.0 Mol F: C15H28BNO2 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (S)-3-Methyl-1-((3aR,4R,6R,7aS)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-amine 2,2,2-trifluoroacetate

Bortezomib Impurity 33

CAT No: CL-BTZ-36 CAS No: 948294-96-0 Mol Wt: 278.2 Mol F: C14H23BN2O3 Inv Status: Custom Synthesis

Chemical Name: ((R)-1-((S)-2-Amino-3-phenylpropanamido)-3-methylbutyl)boronicacid;B-[(1R)-1-[[(2S)-2-Amino-1-oxo-3-phenylpropyl]amino]-3-methylbutyl]boronic acid

Bortezomib Impurity 34

CAT No: CL-BTZ-37 CAS No: NA Mol Wt: 298.3 Mol F: C15H14N4O3 Inv Status: Custom Synthesis

Chemical Name: N-(1-Formamido-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 35

CAT No: CL-BTZ-38 CAS No: NA Mol Wt: 531.4 Mol F: C28H34BN5O5 Inv Status: Custom Synthesis

Chemical Name: ((R)-3-methyl-1-((R)-3-phenyl-2-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic acid

Bortezomib Impurity 36

CAT No: CL-BTZ-39 CAS No: 114457-94-2 Mol Wt: 271.3 Mol F: C14H13N3O3 Inv Status: Custom Synthesis

Chemical Name: (S)-3-phenyl-2-(pyrazine-2-carboxamido)propanoic acid

Bortezomib Related Impurity E

CAT No: CL-BTZ-40 CAS No: NA Mol Wt: 370.5 Mol F: C20H26N4O3 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((R)-1-Methoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Related Impurity F

CAT No: CL-BTZ-41 CAS No: NA Mol Wt: 370.5 Mol F: C20H26N4O3 Inv Status: Custom Synthesis

Chemical Name: (2S)-3-Phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoic acid methyl ester

Bortezomib Impurity A

CAT No: CL-BTZ-42 CAS No: 289472-80-6 Mol Wt: 270.3 Mol F: C14H14N4O2 Inv Status: Custom Synthesis

Chemical Name: N-[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]pyrazinecarboxamide

Bortezomib Impurity C (Mixture Of Isomers)

CAT No: CL-BTZ-43 CAS No: NA Mol Wt: 384.3 Mol F: C19H25BN4O4 Inv Status: Custom Synthesis

Chemical Name: (1-((S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanamido)pentyl)boronic acid

Bortezomib Impurity F

CAT No: CL-BTZ-44 CAS No: 73058-37-4 Mol Wt: 285.3 Mol F: C15H15N3O3 Inv Status: Custom Synthesis

Chemical Name: (2S)-3-Phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoic acid methyl ester

Bortezomib Impurity G

CAT No: CL-BTZ-45 CAS No: 289472-81-7 Mol Wt: 356.4 Mol F: C19H24N4O3 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((S)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity H

CAT No: CL-BTZ-46 CAS No: 1446194-56-4 Mol Wt: 340.4 Mol F: C19H24N4O2 Inv Status: Custom Synthesis

Chemical Name: N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide

Bortezomib Impurity M

CAT No: CL-BTZ-47 CAS No: NA Mol Wt: 372.4 Mol F: C19H24N4O4 Inv Status: Custom Synthesis

Chemical Name: N-((R)-1-(((S)-1-Hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity N

CAT No: CL-BTZ-48 CAS No: NA Mol Wt: 372.4 Mol F: C19H24N4O4 Inv Status: Custom Synthesis

Chemical Name: N-((R)-1-(((R)-1-Hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Intermediate(R,S)

CAT No: CL-BTZ-49 CAS No: 2363753-37-9 Mol Wt: 236.2 Mol F: C14H25BO2 Inv Status: Custom Synthesis

Chemical Name: (3aR,4R,6R)-2-isobutyl-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole

Bortezomib Intermediate(S,R)

CAT No: CL-BTZ-50 CAS No: 84110-34-9 Mol Wt: 236.2 Mol F: C14H25BO2 Inv Status: Custom Synthesis

Chemical Name: (3aS,4S,6S,7aR)-2-Isobutyl-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole

Bortezomib R-Hydroperoxide

CAT No: CL-BTZ-52 CAS No: 886979-78-8 Mol Wt: 372.4 Mol F: C19H24N4O4 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((R)-1-hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide compound with N-((S)-1-(((S)-1-hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide (1:1)

Bortezomib S-Hydroperoxide

CAT No: CL-BTZ-53 CAS No: 886979-81-3 Mol Wt: 372.4 Mol F: C19H24N4O4 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-((S)-1-Hydroperoxy-3-methylbutylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Amino R Isomer

CAT No: CL-BTZ-54 CAS No: 179324-87-9 Mol Wt: 265.2 : 114.0 Mol F: C15H28BNO2 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (R)-3-Methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-amine 2,2,2-trifluoroacetate

Bortezomib Isoamyl Impurity

CAT No: CL-BTZ-55 CAS No: 1375004-39-9 Mol Wt: 518.5 Mol F: C29H39BN4O4 Inv Status: Custom Synthesis

Chemical Name: N-((R)-1-(((R)-3-Methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 37

CAT No: CL-BTZ-56 CAS No: 1798895-16-5 Mol Wt: 285.3 Mol F: C15H15N3O3 Inv Status: Custom Synthesis

Chemical Name: Methyl (pyrazine-2-carbonyl)-D-phenylalaninate

Bortezomib Related Compaund E

CAT No: CL-BTZ-57 CAS No: NA Mol Wt: 298.3 Mol F: C15H14N4O3 Inv Status: Custom Synthesis

Chemical Name: (S)-N-(1-Formamido-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Related Compaund K

CAT No: CL-BTZ-59 CAS No: NA Mol Wt: 711.8 Mol F: C38H47N8O6 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((R)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide compound with N-((S)-1-(((S)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide (1:1)

Bortezomib Related Compaund N

CAT No: CL-BTZ-60 CAS No: NA Mol Wt: 356.4 Mol F: C19H24N4O3 Inv Status: Custom Synthesis

Chemical Name: N-((R)-1-(((R)-1-Hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Related Compaund P

CAT No: CL-BTZ-62 CAS No: NA Mol Wt: 531.4 Mol F: C28H34BN5O5 Inv Status: Custom Synthesis

Chemical Name: NA

Bortezomib Impurity 40

CAT No: CL-BTZ-63 CAS No: 85167-14-2 Mol Wt: 284.6 Mol F: C15H26BClO2 Inv Status: Custom Synthesis

Chemical Name: (3aS,4S,6S,7aR)-2-((S)-1-Chloro-3-methylbutyl)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole

Bortezomib R And S Hydroperoxide

CAT No: CL-BTZ-64 CAS No: NA Mol Wt: 2(372.4) Mol F: 2(C19H24N4O4) Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((R)-1-hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide compound with N-((S)-1-(((S)-1-hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide (1:1)

(S,R)-Bortezomib Hydroxyisopentyl Amide Analog

CAT No: CL-BTZ-65 CAS No: 289472-78-2 Mol Wt: 356.4 Mol F: C19H24N4O3 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Related Compound E

CAT No: CL-BTZ-66 CAS No: NA Mol Wt: 298.3 Mol F: C15H14N4O3 Inv Status: Custom Synthesis

Chemical Name: (S)-N-(1-Formamido-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Related Compound P

CAT No: CL-BTZ-67 CAS No: NA Mol Wt: 531.4 Mol F: C28H34BN5O5 Inv Status: Custom Synthesis

Chemical Name: ((R)-3-Methyl-1-((S)-3-phenyl-2-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic acid

(Pyrazine-2-carbonyl)-D-phenylalanine

CAT No: CL-BTZ-68 CAS No: 1608986-16-8 Mol Wt: 271.3 Mol F: C14H13N3O3 Inv Status: Custom Synthesis

Chemical Name: (Pyrazine-2-carbonyl)-D-phenylalanine

Bortezomib Hydroxy Ketone Analog

CAT No: CL-BTZ-69 CAS No: 2379402-85-2 Mol Wt: 370.4 Mol F: C19H22N4O4 Inv Status: Custom Synthesis

Chemical Name: (S)-N-(1-(3-hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib D-Mannitol Ester

CAT No: CL-BTZ-70 CAS No: 444576-08-3 Mol Wt: 530.4 Mol F: C25H35BN4O8 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((R)-1-((4R,5R)-4,5-Bis((R)-1,2-dihydroxyethyl)-1,3,2-dioxaborolan-2-yl)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Ester Impurity

CAT No: CL-BTZ-71 CAS No: NA Mol Wt: 518.5 Mol F: C29H39BN4O4 Inv Status: Custom Synthesis

Chemical Name: N-(1-((3-methyl-1-(3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity B

CAT No: CL-BTZ-72 CAS No: NA Mol Wt: 520.4 Mol F: C28H37BN4O5 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((R)-3-Mhyl-1-((3aR,5S,7R,7aS)-6,6,7a-trimethyltetrahydro-5H-5,7-methano[1,3,2]dioxaborolo[4,5-b]pyran-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Desisobutyl-n-butyl Bortezomib

CAT No: CL-BTZ-73 CAS No: 1104011-35-9 Mol Wt: 384.2 Mol F: C19H25BN4O4 Inv Status: Custom Synthesis

Chemical Name: ((R)-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)pentyl)boronic acid

Phenylalanine Dimer Impurity

CAT No: CL-BTZ-74 CAS No: NA Mol Wt: 404.4 Mol F: C22H20N4O4 Inv Status: Custom Synthesis

Chemical Name: 2-Phenyl-2-(3-phenyl-2-(pyrazine-2-carboxamido)propanamido)acetic acid

Bortezomib Impurity 38

CAT No: CL-BTZ-75 CAS No: 18680-27-8 Mol Wt: 170.3 Mol F: C10H18O2 Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol

Bortezomib Impurity 41

CAT No: CL-BTZ-76 CAS No: 514820-48-5 Mol Wt: 409.6 Mol F: C21H44BNO2Si2 Inv Status: Custom Synthesis

Chemical Name: 1,1,1-Trimethyl-N-((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)-N-(trimethylsilyl)silanamine

Bortezomib Impurity 42 Trifluoroacetate

CAT No: CL-BTZ-77 CAS No: 477254-69-6 Mol Wt: 265.2 : 114.0 Mol F: C15H28BNO2 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (S)-3-Methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-amine 2,2,2-trifluoroacetate

Bortezomib Impurity 43

CAT No: CL-BTZ-78 CAS No: NA Mol Wt: 504.4 Mol F: C28H37BN4O4 Inv Status: Custom Synthesis

Chemical Name: Pyrazine-2-carboxylic acid (1-[3-methyl-1-(2,9-dimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0.2.6]dec-4-yl)-butylcarbamoyl]-2-phenyl-ethyl)-amide

Bortezomib Impurity 44

CAT No: CL-BTZ-79 CAS No: 2308-61-4 Mol Wt: 294.4 Mol F: C18H18N2O2 Inv Status: Custom Synthesis

Chemical Name: 3,6-Dibenzylpiperazine-2,5-dione

Bortezomib Impurity 45

CAT No: CL-BTZ-80 CAS No: 1255646-95-7 Mol Wt: 298.3 Mol F: C17H18N2O3 Inv Status: Custom Synthesis

Chemical Name: (S)-2-((S)-2-amino-3-phenylpropanamido)-2-phenylacetic acid

Bortezomib Impurity 46

CAT No: CL-BTZ-81 CAS No: 2577-40-4 Mol Wt: 312.4 Mol F: C18H20N2O3 Inv Status: Custom Synthesis

Chemical Name: L-Phenylalanyl-L-phenylalanine

Bortezomib Impurity 47

CAT No: CL-BTZ-82 CAS No: 1194235-14-7 Mol Wt: 418.5 Mol F: C23H22N4O4 Inv Status: Custom Synthesis

Chemical Name: (Pyrazine-2-carbonyl)-L-phenylalanyl-L-phenylalanine

Bortezomib Impurity 48

CAT No: CL-BTZ-83 CAS No: NA Mol Wt: 1098.7 Mol F: C57H69B3N12O9 Inv Status: Custom Synthesis

Chemical Name: N,N',N''-((2R,2'R,2''R)-(((1S,1'S,1''S)-(1,3,5,2,4,6-Trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(1-oxo-3-phenylpropane-1,2-diyl))tris(pyrazine-2-carboxamide)

Bortezomib Impurity 49

CAT No: CL-BTZ-84 CAS No: NA Mol Wt: 1098.7 Mol F: C57H69B3N12O9 Inv Status: Custom Synthesis

Chemical Name: N,N',N''-((2S,2'S,2''S)-(((1S,1'S,1''S)-(1,3,5,2,4,6-Trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(1-oxo-3-phenylpropane-1,2-diyl))tris(pyrazine-2-carboxamide)

Bortezomib Impurity 50

CAT No: CL-BTZ-85 CAS No: NA Mol Wt: 1098.7 Mol F: C57H69B3N12O9 Inv Status: Custom Synthesis

Chemical Name: N,N',N''-((2R,2'R,2''R)-(((1R,1'R,1''R)-(1,3,5,2,4,6-Trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(1-oxo-3-phenylpropane-1,2-diyl))tris(pyrazine-2-carboxamide)

Bortezomib Impurity 51

CAT No: CL-BTZ-86 CAS No: NA Mol Wt: 490.4 Mol F: C27H35BN4O4 Inv Status: Custom Synthesis

Chemical Name: N-(1-Oxo-3-phenyl-1-((1-(3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)propyl)amino)propan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 53

CAT No: CL-BTZ-87 CAS No: 2364553-64-8 Mol Wt: 271.3 Mol F: C14H13N3O3 Inv Status: Custom Synthesis

Chemical Name: 3-Phenyl-2(pyrazine-2-carboxamido) propanoic acid

Bortezomib Impurity 54

CAT No: CL-BTZ-88 CAS No: 110755-29-8 Mol Wt: 234.3 Mol F: C14H22N2O Inv Status: Custom Synthesis

Chemical Name: (S)-2-Amino-N-isopentyl-3-phenylpropanamide

Bortezomib Impurity 56

CAT No: CL-BTZ-89 CAS No: 4664-57-7 Mol Wt: 228.3 Mol F: C11H16O3S Inv Status: Custom Synthesis

Chemical Name: Tert-butyl 4-methylbenzenesulfonate

Bortezomib Impurity 70

CAT No: CL-BTZ-90 CAS No: NA Mol Wt: 384.2 Mol F: C19H25BN4O4 Inv Status: Custom Synthesis

Chemical Name: ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid compound with ((S)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid

Bortezomib Impurity 71

CAT No: CL-BTZ-91 CAS No: 1579304-37-2 Mol Wt: 518.5 Mol F: C29H39BN4O4 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((R)-3-Methyl-1-((3aR,4R,6R,7aS)-3a,5,5-Trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 72

CAT No: CL-BTZ-92 CAS No: NA Mol Wt: 414.5 Mol F: C22H30N4O4 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((R)-1-(((S)-1-Hydroxypropan-2-yl)oxy)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 73

CAT No: CL-BTZ-93 CAS No: NA Mol Wt: 414.5 Mol F: C22H30N4O4 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((R)-1-((S)-2-Hydroxypropoxy)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 74

CAT No: CL-BTZ-94 CAS No: NA Mol Wt: 414.5 Mol F: C22H30N4O4 Inv Status: Custom Synthesis

Chemical Name: N-((S)-1-(((R)-1-((R)-2-Hydroxypropoxy)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 76

CAT No: CL-BTZ-95 CAS No: NA Mol Wt: 340.4 Mol F: C19H24N4O2 Inv Status: Custom Synthesis

Chemical Name: N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 77

CAT No: CL-BTZ-96 CAS No: NA Mol Wt: 356.4 Mol F: C19H24N4O3 Inv Status: Custom Synthesis

Chemical Name: N-(1-((1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 78

CAT No: CL-BTZ-97 CAS No: NA Mol Wt: 409.6 Mol F: C21H44BNO2Si2 Inv Status: Custom Synthesis

Chemical Name: 1,1,1-Trimethyl-N-((S)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)-N-(trimethylsilyl)silanamine

Bortezomib Impurity 79

CAT No: CL-BTZ-98 CAS No: NA Mol Wt: 518.5 Mol F: C29H39BN4O4 Inv Status: Custom Synthesis

Chemical Name: N-(1-((3-Methyl-1-((3aS,4S,6S,7aS)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impurity 81

CAT No: CL-BTZ-99 CAS No: NA Mol Wt: 481.4 Mol F: C25H36BN5O4 Inv Status: Custom Synthesis

Chemical Name: (2R,4R,8S)-2,6-dimethyl-8-((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)hexahydro-[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide

Bortezomib Impurity 82

CAT No: CL-BTZ-100 CAS No: 2304059-57-0 Mol Wt: 285.3 Mol F: C15H15N3O3 Inv Status: Custom Synthesis

Chemical Name: Methyl (pyrazine-2-carbonyl)phenylalaninate

Bortezomib D5

CAT No: CL-BTZ-101 CAS No: 1133706-15-6 Mol Wt: 389.3 Mol F: C19H20D5BN4O4 Inv Status: Custom Synthesis

Chemical Name: ((R)-3-Methyl-1-((S)-3-(phenyl-d5)-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid

Type:Impurity Reference Standard

API NAME:Bortezomib

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