Impurity Reference Standard - Products

Carfilzomib

CAT No: CL-CFZB-01 CAS No: 868540-17-4 Mol Wt: 719.9 Mol F: C40H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (aS)-a-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide

Carfilzomib (2R,4R)-Diol

CAT No: CL-CFZB-02 CAS No: 2049025-83-2 Mol Wt: 737.9 Mol F: C40H59N5O8 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((S)-1-(((2R,4R)-1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib (2R,4S)-Diol

CAT No: CL-CFZB-03 CAS No: 1541172-75-1 Mol Wt: 737.9 Mol F: C40H59N5O8 Inv Status: Custom Synthesis

Chemical Name: (aS)?-?a-?[[2-?(4-?Morpholinyl)?acetyl]?amino]?benzenebutanoyl-?L-?leucyl-?N-?[(1S,?3R)?-?3,?4-?dihydroxy-?3-?methyl-?1-?(2-?methylpropyl)?-?2-?oxobutyl]?-L-?phenylalaninamide

Carfilzomib (2S,4R)-Diol

CAT No: CL-CFZB-04 CAS No: NA Mol Wt: 737.9 Mol F: C40H59N5O8 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((S)-1-(((2S,4R)-1,2-Dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Dimer Impurity 1

CAT No: CL-CFZB-05 CAS No: NA Mol Wt: 1141.5 Mol F: C65H88N8O10 Inv Status: Custom Synthesis

Chemical Name: (S)-2-((2S,5S,8S,11S)-5-Benzyl-8-isobutyl-14-morpholino-4,7,10,13-tetraoxo-2,11-diphenethyl-3,6,9,12-tetraazatetradecanamido)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R )-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide

Carfilzomib Dimer Impurity 2

CAT No: CL-CFZB-06 CAS No: NA Mol Wt: 980.3 Mol F: C55H77N7O9 Inv Status: Custom Synthesis

Chemical Name: (S)-4-Methyl-N-((S)-1-(((S)-4-methyl-1-(((S)-1-(((S)-4-methyl-1-((R )-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Dimer Impurity 3

CAT No: CL-CFZB-07 CAS No: NA Mol Wt: 1440.9 Mol F: C80H115N10O14 Inv Status: Custom Synthesis

Chemical Name: 4-((4S,7S,10S,13S)-10-benzyl-15-hydroxy-7,13-diisobutyl-15-methyl-1-morpholino-2,5,8,11,14-pentaoxo-4-phenethyl-3,6,9,12-tetraazahexadecan-16-yl)-4-((4S,7S,10S,13S)-10-benzyl-7-isobutyl-15-methyl-13-((R)-2-methyloxirane-2-carbonyl)-2,5,8,11-tetraoxo-4-phenethyl-3,6,9,12-tetraazahexadecyl)morpholin-4-ium

Carfilzomib Dimer Impurity 4

CAT No: CL-CFZB-08 CAS No: NA Mol Wt: 1440.9 Mol F: C80H115N10O14 Inv Status: Custom Synthesis

Chemical Name: 2-((4S,7S,10S,13S)-10-benzyl-7-isobutyl-15-methyl-1-morpholino-2,5,8,11-tetraoxo-4-phenethyl-3,6,9,12-tetraazahexadecan-13-yl)-2,3-dihydroxy-3-methyl-1-(((S)-1-(((S)-4-methyl-1-(((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopentan-2-yl)amino)-1-oxo-4-phenylbutan-2-yl)carbamoyl)-8-oxa-5-azaspiro[4.5]decan-5-ium

Carfilzomib Methoxide

CAT No: CL-CFZB-09 CAS No: 1140908-89-9 Mol Wt: 580.7 Mol F: C32H44N4O6 Inv Status: Custom Synthesis

Chemical Name: Methyl ((S)-2-(2-morpholinoacetamido)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate

Carfilzomib N-Oxide Impurity

CAT No: CL-CFZB-10 CAS No: 1672698-96-2 Mol Wt: 735.9 Mol F: C40H57N5O8 Inv Status: Custom Synthesis

Chemical Name: 4-((4S,7S,10S,13S)-10-Benzyl-7-isobutyl-15-methyl-13-((R)-2-methyloxirane-2-carbonyl)-2,5,8,11-tetraoxo-4-phenethyl-3,6,9,12-tetraazahexadecyl)morpholine 4-oxide

4-Morpholineacetic Acid Hydrochloride

CAT No: CL-CFZB-11 CAS No: 89531-58-8 Mol Wt: 145.2 : 36.5 Mol F: C6H11NO3 : HCl Inv Status: Custom Synthesis

Chemical Name: 2-Morpholinoacetic acid hydrochloride

7(R)-Epi Carfilzomib (2R,4S)-Diol

CAT No: CL-CFZB-12 CAS No: NA Mol Wt: 737.9 Mol F: C40H59N5O8 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((R)-1-(((2R,4S)-1,2-Dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

7(R)-Epi Carfilzomib (2S,4S)-Diol

CAT No: CL-CFZB-13 CAS No: NA Mol Wt: 737.9 Mol F: C40H59N5O8 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((R)-1-(((2S,4S)-1,2-Dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib (2R,4S)-2-Hydroxy Acetate

CAT No: CL-CFZB-14 CAS No: 1541171-69-0 Mol Wt: 780 Mol F: C42H61N5O9 Inv Status: Custom Synthesis

Chemical Name: (4S,7S,10S,13S,15R)-10-Benzyl-15-hydroxy-7,13-diisobutyl-15-methyl-1-morpholino-2,5,8,11,14-pentaoxo-4-phenethyl-3,6,9,12-tetraazahexadecan-16-yl acetate

Carfilzomib (2S,4R)-1,2-Hydroxy-O-Acetate

CAT No: CL-CFZB-15 CAS No: NA Mol Wt: 780 Mol F: C42H61N5O9 Inv Status: Custom Synthesis

Chemical Name: (4S,7S,10S,13R,15S)-10-benzyl-15-hydroxy-7,13-diisobutyl-15-methyl-1-morpholino-2,5,8,11,14-pentaoxo-4-phenethyl-3,6,9,12-tetraazahexadecan-16-yl acetate

Carfilzomib 2-Acetate

CAT No: CL-CFZB-16 CAS No: NA Mol Wt: 780 Mol F: C42H61N5O9 Inv Status: Custom Synthesis

Chemical Name: (4S,7S,10S,13R,15R)-10-Benzyl-15-hydroxy-7,13-diisobutyl-15-methyl-1-morpholino-2,5,8,11,14-pentaoxo-4-phenethyl-3,6,9,12-tetraazahexadecan-16-yl acetate

Carfilzomib Amide Dimer

CAT No: CL-CFZB-17 CAS No: NA Mol Wt: 1129.4 Mol F: C62H84N10O10 Inv Status: Custom Synthesis

Chemical Name: NA

Carfilzomib Impurity B

CAT No: CL-CFZB-18 CAS No: NA Mol Wt: 737.9 Mol F: C40H59N5O8 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((R)-1-(((2R,4R)-1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Peptide Epoxide Carfilzomib

CAT No: CL-CFZB-19 CAS No: NA Mol Wt: 592.8 Mol F: C34H48N4O5 Inv Status: Custom Synthesis

Chemical Name: (2S)-2-((S)-2-Amino-4-phenylbutanamido)-4-methyl-N-((2S)-1-(((2R)-4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide

Carfilzomib Related Impurity (HCl salt)

CAT No: CL-CFZB-20 CAS No: 168154-76-5 Mol Wt: 193.2 : 36.5 Mol F: C10H11NO3 : HCl Inv Status: Custom Synthesis

Chemical Name: (S)-4-Oxo-homophenylalanine Hydrochloride

Carfilzomib Impurity 1 (RSSSS)

CAT No: CL-CFZB-21 CAS No: NA Mol Wt: 912 Mol F: C46H65N5O14 Inv Status: Custom Synthesis

Chemical Name: 2-((4S,7S,10S,13S)-10-benzyl-15-hydroxy-7,13-diisobutyl-15-methyl-1-morpholino-2,5,8,11,14,18-hexaoxo-4-phenethyl-17-oxa-3,6,9,12-tetraazanonadecan-19-yl)-2-hydroxysuccinic acid

Carfilzomib Impurity 3 (SSRSR)

CAT No: CL-CFZB-22 CAS No: NA Mol Wt: 737.9 Mol F: C40H59N5O8 Inv Status: Custom Synthesis

Chemical Name: (2S)-N-[(1R)-1-{[(2S,4S)-1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl]carbamoyl}-2-phenylethyl]-4-methyl-2-[(2R)-2-[2-(morpholin-4-yl)acetamido]-4-phenylbutanamido]pentanamide

Carfilzomib Impurity 5 (RSSSS)

CAT No: CL-CFZB-23 CAS No: 1545469-02-0 Mol Wt: 592.8 : 114.0 Mol F: C34H48N4O5 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (S)-2-((S)-2-Amino-4-phenylbutanamido)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide 2,2,2-trifluoroacetate

Carfilzomib Impurity 6 (SSSSS)

CAT No: CL-CFZB-24 CAS No: 1672698-88-2 Mol Wt: 719.9 Mol F: C40H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 7 (RRSSS)

CAT No: CL-CFZB-25 CAS No: 2049025-76-3 Mol Wt: 719.9 Mol F: C40H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-4-methyl-N-((S)-1-(((R)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 8 (SSSS)

CAT No: CL-CFZB-26 CAS No: 1660143-42-9 Mol Wt: 703.9 Mol F: C40H57N5O6 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((S)-1-(((S)-2,6-dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 9 (RSSSS)

CAT No: CL-CFZB-27 CAS No: 868540-22-1 Mol Wt: 692.9 Mol F: C39H56N4O7 Inv Status: Custom Synthesis

Chemical Name: (2R)-2-[(2S)-2-[[N-[(S)-2-(tert-Butoxycarbonylamino)-4-phenylbutanoyl]-L-leucyl-L-phenylalanyl]amino]-4-methylpentanoyl]-2-methyloxirane

Carfilzomib Impurity 10 (RSSSR)

CAT No: CL-CFZB-28 CAS No: 2049025-59-2 Mol Wt: 719.9 Mol F: C40H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-4-Methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 12 (SRSSS)

CAT No: CL-CFZB-29 CAS No: 2049025-67-2 Mol Wt: 719.9 Mol F: C40H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-4-Methyl-N-((S)-1-(((R)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 13

CAT No: CL-CFZB-30 CAS No: 1396006-45-3 Mol Wt: 306.4 Mol F: C16H22N2O4 Inv Status: Custom Synthesis

Chemical Name: (S)-2-(2-Morpholinoacetamido)-4-phenylbutanoic acid

Carfilzomib Impurity 14 (SS)

CAT No: CL-CFZB-31 CAS No: 1396006-47-5 Mol Wt: 419.5 Mol F: C22H33N3O5 Inv Status: Custom Synthesis

Chemical Name: ((S)-2-(2-Morpholinoacetamido)-4-phenylbutanoyl)-L-leucine

Carfilzomib Impurity 16 (SSSSS)

CAT No: CL-CFZB-32 CAS No: 1396006-50-0 Mol Wt: 737.9 Mol F: C40H59N5O8 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((S)-1-(((2S,4S)-1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 17 (SS)

CAT No: CL-CFZB-33 CAS No: 247068-83-3 Mol Wt: 271.4 Mol F: C14H25NO4 Inv Status: Custom Synthesis

Chemical Name: Tert-butyl ((S)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate

Carfilzomib Impurity 18

CAT No: CL-CFZB-34 CAS No: NA Mol Wt: 719.9 Mol F: C40H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (2S,3R)-3-Methyl-N-((S)-1-(((S)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 19 (SS)

CAT No: CL-CFZB-35 CAS No: 2828545-92-0 Mol Wt: 267.3 Mol F: C11H16F3NO3 Inv Status: Custom Synthesis

Chemical Name: 2,2,2-Trifluoro-N-((S)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)acetamide

Carfilzomib Impurity 20 (SSRSS)

CAT No: CL-CFZB-36 CAS No: NA Mol Wt: 719.9 Mol F: C40H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-4-Methyl-N-((R)-1-(((S)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 21

CAT No: CL-CFZB-37 CAS No: NA Mol Wt: 719.9 Mol F: C40H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-4-Methyl-N-((S)-1-(((2S,3S)-3-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 23

CAT No: CL-CFZB-38 CAS No: 247068-82-2 Mol Wt: 271.4 Mol F: C14H25NO4 Inv Status: Custom Synthesis

Chemical Name: Tert-butyl ((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate

Carfilzomib Impurity 24 (Trifluoroacetate Salt)

CAT No: CL-CFZB-39 CAS No: 247068-85-5 Mol Wt: 171.2 : 114.0 Mol F: C9H17NO2 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (S)-2-Amino-4-methyl-1-((R)-2-methyloxiran-2-yl)pentan-1-one 2,2,2-trifluoroacetate

Carfilzomib Impurity 28

CAT No: CL-CFZB-40 CAS No: 2049025-49-0 Mol Wt: 719.9 Mol F: C40H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-4-Methyl-N-((R)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 31

CAT No: CL-CFZB-41 CAS No: NA Mol Wt: 756.4 Mol F: C40H58ClN5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((S)-1-(((2R,4S)-1-chloro-2-hydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 32

CAT No: CL-CFZB-42 CAS No: 868540-16-3 Mol Wt: 566.7 Mol F: C31H42N4O6 Inv Status: Custom Synthesis

Chemical Name: ((S)-2-(2-Morpholinoacetamido)-4-phenylbutanoyl)-L-leucyl-L-phenylalanine

Carfilzomib Impurity 33

CAT No: CL-CFZB-43 CAS No: NA Mol Wt: 719.9 Mol F: C40H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (R)-4-Methyl-N-((R)-1-(((R)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl) amino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-morpholinoacetamido)-4-phenylbutanamido) pentanamide

Carfilzomib Impurity 34 (Trifluoroacetate Salt)

CAT No: CL-CFZB-44 CAS No: 1800500-63-3 Mol Wt: 171.2 : 114.0 Mol F: C9H17NO2 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: 4-?Amino-?1,?2-?anhydro-?4,?5,?6,?7-?tetradeoxy-?5-?methyl-?2-?C-?methyl-L-?ribo-?3-?heptulose 2,?2,?2-?Trifluoroacetate

Carfilzomib Impurity 35 (Trifluoroacetate Salt)

CAT No: CL-CFZB-45 CAS No: 1619233-32-7 Mol Wt: 155.2 : 114.0 Mol F: C9H17NO : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (4S)-4-Amino-2,6-dimethyl-1-hepten-3-one 2,2,2-Trifluoroacetate

Carfilzomib Impurity 36 (Trifluoroacetate Salt)

CAT No: CL-CFZB-46 CAS No: 1528769-14-3 Mol Wt: 171.2 : 114.0 Mol F: C9H17NO2 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (S)-2-Amino-4-methyl-1-((S)-2-methyloxiran-2-yl)pentan-1-one Trifluoroacetate Salt

Carfilzomib Impurity 37 (Trifluoroacetate Salt)

CAT No: CL-CFZB-47 CAS No: 2518419-39-9 Mol Wt: 231.3 : 114.0 Mol F: C11H21NO4 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (2S,4S)-4-Amino-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate Trifluoroacetic Acid Salt

Carfilzomib Impurity 38 (Trifluoroacetate Salt)

CAT No: CL-CFZB-48 CAS No: 2802917-76-4 Mol Wt: 345.3 : 114.0 Mol F: C13H22F3NO6 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (2R,4S)-4-Amino-2-hydroxy-2,6-dimethyl-3-oxoheptyl acetate 2,2,2-trifluoroacetate

Carfilzomib Impurity 39

CAT No: CL-CFZB-49 CAS No: 2049024-22-6 Mol Wt: 629.8 Mol F: C37H47N3O6 Inv Status: Custom Synthesis

Chemical Name: (6S,9R,12S)-Benzyl 12-Benzyl-9-isobutyl-2,2-dimethyl-4,7,10-trioxo-6-phenethyl-3-oxa-5,8,11-triazatridecan-13-oate

Carfilzomib Impurity 40

CAT No: CL-CFZB-50 CAS No: 2177287-70-4 Mol Wt: 255.4 Mol F: C14H25NO3 Inv Status: Custom Synthesis

Chemical Name: (R)-t-Butyl (2,6-Dimethyl-3-oxohept-1-en-4-yl)carbamate

Carfilzomib Impurity 41

CAT No: CL-CFZB-51 CAS No: 247068-81-1 Mol Wt: 255.4 Mol F: C14H25NO3 Inv Status: Custom Synthesis

Chemical Name: Tert-Butyl ((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)carbamate

Carfilzomib Impurity 42

CAT No: CL-CFZB-52 CAS No: 2177287-68-0 Mol Wt: 271.4 Mol F: C14H25NO4 Inv Status: Custom Synthesis

Chemical Name: Tert-butyl ((R)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate

Carfilzomib Impurity 43

CAT No: CL-CFZB-53 CAS No: NA Mol Wt: 331.4 Mol F: C16H29NO6 Inv Status: Custom Synthesis

Chemical Name: (2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate

Carfilzomib Impurity 44

CAT No: CL-CFZB-54 CAS No: NA Mol Wt: 331.4 Mol F: C16H29NO6 Inv Status: Custom Synthesis

Chemical Name: (2R,4S)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate

Carfilzomib Impurity 45

CAT No: CL-CFZB-55 CAS No: 2768679-89-4 Mol Wt: 635.8 Mol F: C37H53N3O6 Inv Status: Custom Synthesis

Chemical Name: (6S,9S,12S)-Benzyl 12-Benzyl-6-(2-cyclohexylethyl)-9-isobutyl-2,2-dimethyl-4,7,10-trioxo-3-oxa-5,8,11-triazatridecan-13-oate

Carfilzomib Impurity 46

CAT No: CL-CFZB-56 CAS No: NA Mol Wt: 572.7 Mol F: C31H48N4O6 Inv Status: Custom Synthesis

Chemical Name: (S)-2-((S)-2-((S)-4-Cyclohexyl-2-(2-morpholinoacetamido)butanamido)-4-methylpentanamido)-3-phenylpropanoic Acid

Carfilzomib Impurity 47

CAT No: CL-CFZB-57 CAS No: 72080-89-8 Mol Wt: 258.4 Mol F: C13H26N2O3 Inv Status: Custom Synthesis

Chemical Name: N-[(1S)-1-[(Dimethylamino)carbonyl]-3-methylbutyl]-carbamic Acid 1,1-Dimethylethyl Ester

Carfilzomib Impurity 48

CAT No: CL-CFZB-58 CAS No: 2145198-41-8 Mol Wt: 257.4 Mol F: C14H27NO3 Inv Status: Custom Synthesis

Chemical Name: Tert-butyl ((4R)-3-hydroxy-2,6-dimethylhept-1-en-4-yl)carbamate

Carfilzomib Impurity 49

CAT No: CL-CFZB-59 CAS No: 1609959-45-6 Mol Wt: 257.4 Mol F: C14H27NO3 Inv Status: Custom Synthesis

Chemical Name: N-[(1S)-2-Hydroxy-3-methyl-1-(2-methylpropyl)-3-buten-1-yl]-carbamic Acid 1,1-Dimethylethyl Ester

Carfilzomib Impurity 50

CAT No: CL-CFZB-60 CAS No: 129603-01-6 Mol Wt: 274.4 Mol F: C13H26N2O4 Inv Status: Custom Synthesis

Chemical Name: N-?[(1R)?-?1-?[(Methoxymethylamino?)?carbonyl]?-?3-?methylbutyl]?-carbamic Acid 1,?1-?Dimethylethyl Ester

Carfilzomib Impurity 52

CAT No: CL-CFZB-61 CAS No: 1541171-67-8 Mol Wt: 756.4 Mol F: C40H58ClN5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((S)-1-(((2S,4S)-1-chloro-2-hydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 53

CAT No: CL-CFZB-62 CAS No: 2049025-45-6 Mol Wt: 719.9 Mol F: C40H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (R)-4-Methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 54

CAT No: CL-CFZB-63 CAS No: NA Mol Wt: 691.9 Mol F: C39H55N4O7 Inv Status: Custom Synthesis

Chemical Name: Tert-butyl-((S)-1-(((S)-4-methyl-1-(((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopentan-2-yl)amino)-1-oxo-4-phenylbutan-2-yl)carbamate

Carfilzomib Impurity 55

CAT No: CL-CFZB-64 CAS No: 2419266-62-7 Mol Wt: 719.9 Mol F: C40H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-4-Methyl-N-((R)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 56

CAT No: CL-CFZB-65 CAS No: 2049024-37-3 Mol Wt: 629.8 Mol F: C37H47N3O6 Inv Status: Custom Synthesis

Chemical Name: Benzyl ((R)-2-((tert-butoxycarbonyl)amino)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate

Carfilzomib Impurity 57

CAT No: CL-CFZB-66 CAS No: 143415-51-4 Mol Wt: 285.4 Mol F: C15H27NO4 Inv Status: Custom Synthesis

Chemical Name: (S)-2-((Tert-butoxycarbonyl)amino)-4-cyclohexylbutanoic acid

Carfilzomib Impurity 59

CAT No: CL-CFZB-67 CAS No: 2381627-87-6 Mol Wt: 271.4 Mol F: C14H25NO4 Inv Status: Custom Synthesis

Chemical Name: Tert-butyl ((R)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate

Carfilzomib Impurity 60

CAT No: CL-CFZB-68 CAS No: 875309-82-3 Mol Wt: 529.7 Mol F: C32H39N3O4 Inv Status: Custom Synthesis

Chemical Name: Benzyl ((S)-2-amino-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate

Carfilzomib Impurity 61

CAT No: CL-CFZB-69 CAS No: 1545468-80-1 Mol Wt: 439.6 Mol F: C25H33N3O4 Inv Status: Custom Synthesis

Chemical Name: ((S)-2-Amino-4-phenylbutanoyl)-L-leucyl-L-phenylalanine

Carfilzomib Impurity 62

CAT No: CL-CFZB-70 CAS No: 875309-92-5 Mol Wt: 656.8 Mol F: C38H48N4O6 Inv Status: Custom Synthesis

Chemical Name: Benzyl ((S)-2-(2-morpholinoacetamido)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate

Carfilzomib Impurity 63

CAT No: CL-CFZB-71 CAS No: 2049024-77-1 Mol Wt: 566.7 Mol F: C31H42N4O6 Inv Status: Custom Synthesis

Chemical Name: ((R)-2-(2-Morpholinoacetamido)-4-phenylbutanoyl)-L-leucyl-L-phenylalanine

Carfilzomib Impurity 64

CAT No: CL-CFZB-72 CAS No: 82732-07-8 Mol Wt: 279.3 Mol F: C15H21NO4 Inv Status: Custom Synthesis

Chemical Name: (R)-2-((tert-butoxycarbonyl)amino)-4-phenylbutanoic acid

Carfilzomib Impurity 65

CAT No: CL-CFZB-73 CAS No: 2049024-27-1 Mol Wt: 629.8 Mol F: C37H47N3O6 Inv Status: Custom Synthesis

Chemical Name: Benzyl ((S)-2-((tert-butoxycarbonyl)amino)-4-phenylbutanoyl)-L-leucyl-D-phenylalaninate

Carfilzomib Impurity 66

CAT No: CL-CFZB-74 CAS No: 70637-26-2 Mol Wt: 468.6 Mol F: C27H36N2O5 Inv Status: Custom Synthesis

Chemical Name: Benzyl (tert-butoxycarbonyl)-L-leucyl-L-phenylalaninate

Carfilzomib Impurity 67

CAT No: CL-CFZB-75 CAS No: 70637-27-3 Mol Wt: 368.5 Mol F: C22H28N2O3 Inv Status: Custom Synthesis

Chemical Name: Benzyl L-leucyl-L-phenylalaninate

Carfilzomib Impurity 68 (Trifluoroacetate Salt)

CAT No: CL-CFZB-76 CAS No: NA Mol Wt: 189.3 : 114.0 Mol F: C9H19NO3 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (2R,4S)-4-amino-1,2-dihydroxy-2,6-dimethylheptan-3-one 2,2,2-trifluoroacetate

Carfilzomib Impurity 69

CAT No: CL-CFZB-77 CAS No: 254888-42-1 Mol Wt: 634.8 Mol F: C36H50N4O6 Inv Status: Custom Synthesis

Chemical Name: (S)-2-((S)-2-Acetamido-4-phenylbutanamido)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide

Carfilzomib Impurity 70

CAT No: CL-CFZB-78 CAS No: 1541171-68-9 Mol Wt: 855.1 Mol F: C46H62N8O8 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((S)-1-(((2R,4S)-1-((1H-benzo[d][1,2,3]triazol-1-yl)oxy)-2-hydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 71

CAT No: CL-CFZB-79 CAS No: 868539-98-4 Mol Wt: 453.6 Mol F: C26H35N3O4 Inv Status: Custom Synthesis

Chemical Name: Methyl ((S)-2-amino-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate

Carfilzomib Impurity 72

CAT No: CL-CFZB-80 CAS No: 868539-96-2 Mol Wt: 553.7 Mol F: C31H43N3O6 Inv Status: Custom Synthesis

Chemical Name: Methyl ((S)-2-((tert-butoxycarbonyl)amino)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate

Carfilzomib Impurity 73

CAT No: CL-CFZB-81 CAS No: 1541171-65-6 Mol Wt: 816 Mol F: C41H61N5O10S Inv Status: Custom Synthesis

Chemical Name: (4S,7S,10S,13S,15R)-10-benzyl-15-hydroxy-7,13-diisobutyl-15-methyl-1-morpholino-2,5,8,11,14-pentaoxo-4-phenethyl-3,6,9,12-tetraazahexadecan-16-yl methanesulfonate

Carfilzomib Impurity 74

CAT No: CL-CFZB-82 CAS No: NA Mol Wt: 270.3 Mol F: C14H24NO4 Inv Status: Custom Synthesis

Chemical Name: Tert-butyl((R)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate

Carfilzomib Impurity 75 (Trifluoroacetate Salt)

CAT No: CL-CFZB-83 CAS No: NA Mol Wt: 321.4 : 114.0 Mol F: C17H23NO5 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (S)-2-(((S)-1-Methoxy-1-oxo-3-phenylpropan-2-yl)carbamoyl)-4-methylpentanoic acid compound with 2,2,2-trifluoroacetic acid

Carfilzomib Impurity 76 (Trifluoroacetate Salt)

CAT No: CL-CFZB-84 CAS No: NA Mol Wt: 566.7 : 114.0 Mol F: C32H46N4O5 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: Methyl ((S)-2-amino-4-phenylbutanoyl)-L-leucyl-L-leucyl-L-phenylalaninate trifluoroacetate

Carfilzomib Impurity 77 (Trifluoroacetate Salt)

CAT No: CL-CFZB-85 CAS No: NA Mol Wt: 600.8 : 114.0 Mol F: C35H44N4O5 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: Methyl ((S)-2-amino-4-phenyl butanoyl)-L-Leucyl-L-phenylalanyl-L-Phenylalaninate trifluoroacetate

Carfilzomib Impurity 78

CAT No: CL-CFZB-86 CAS No: 100564-78-1 Mol Wt: 279.3 Mol F: C15H21NO4 Inv Status: Custom Synthesis

Chemical Name: (S)-2-( (tert-butoxycarbonyl)amino)-4-phenylbutanoic acid

Carfilzomib Impurity 79 (Trifluoroacetate Salt)

CAT No: CL-CFZB-87 CAS No: NA Mol Wt: 713.9 : 114.0 Mol F: C41H55N5O6 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: Methyl ((S)-2-amino-4-phenylbutanoyl)-L-leucyl-L-phenylalanyl-L-leucyl-L-phenylalaninate trifluoroacetate

Carfilzomib Impurity 80 (Trifluoroacetate Salt)

CAT No: CL-CFZB-88 CAS No: 2443766-79-6 Mol Wt: 171.2 : 114.0 Mol F: C9H17NO2 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (R)-2-Amino-4-methyl-1-((R)-2-methyloxiran-2-yl)pentan-1-one 2,2,2-trifluoroacetate

Carfilzomib Impurity 82 (Trifluoroacetate Salt)

CAT No: CL-CFZB-89 CAS No: 2436762-87-5 Mol Wt: 171.2 : 114.0 Mol F: C9H17NO2 : C2HF3O2 Inv Status: Custom Synthesis

Chemical Name: (R)-2-Amino-4-methyl-1-((S)-2-methyloxiran-2-yl)pentan-1-one 2,2,2-trifluoroacetate

Carfilzomib Impurity 83

CAT No: CL-CFZB-90 CAS No: NA Mol Wt: 816 Mol F: C41H61N5O10S Inv Status: Custom Synthesis

Chemical Name: (4S,7S,10S,13S,15R)-10-benzyl-15-hydroxy-7,13-diisobutyl-15-methyl-2,5,8,11,14-pentaoxo-4-phenethyl-3,6,9,12-tetraazahexadecan-16-yl morpholinomethanesulfonate

Carfilzomib Impurity 84

CAT No: CL-CFZB-91 CAS No: NA Mol Wt: 707.9 Mol F: C39H57N5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-4-Methyl-N-((S)-1-(((S)-3-methyl-1-(((S)-2-methyloxiran-2-yl)oxy)butyl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 86

CAT No: CL-CFZB-92 CAS No: NA Mol Wt: 734 Mol F: C41H59N5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-4-Methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-(p-tolyl)butanamido)pentanamide

Carfilzomib Impurity 87

CAT No: CL-CFZB-93 CAS No: 890660-08-9 Mol Wt: 481.6 Mol F: C27H35N3O5 Inv Status: Custom Synthesis

Chemical Name: ((S)-2-Acetamido-4-phenylbutanoyl)-L-leucyl-L-phenylalanine

Carfilzomib Impurity 88

CAT No: CL-CFZB-94 CAS No: NA Mol Wt: 988.2 Mol F: C56H73N7O9 Inv Status: Custom Synthesis

Chemical Name: ((S)-2-((S)-2-((S)-4-Methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanamido)-4-phenylbutanoyl)-L-leucyl-L-phenylalanine

Carfilzomib Impurity 89

CAT No: CL-CFZB-95 CAS No: NA Mol Wt: 591.8 Mol F: C34H49N5O4 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((S)-1-(Dimethylamino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-4-phenyl-2-(2-(piperidin-1-yl)acetamido)butanamido)pentanamide

Carfilzomib Impurity 91

CAT No: CL-CFZB-96 CAS No: NA Mol Wt: 593.8 Mol F: C33H47N5O5 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((S)-1-(dimethylamino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 92

CAT No: CL-CFZB-97 CAS No: NA Mol Wt: 833.1 Mol F: C46H68N6O8 Inv Status: Custom Synthesis

Chemical Name: (S)-4-methyl-N-((S)-4-methyl-1-(((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopentan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 93

CAT No: CL-CFZB-98 CAS No: NA Mol Wt: 566.7 Mol F: C31H42N4O6 Inv Status: Custom Synthesis

Chemical Name: ((R)-2-(2-Morpholinoacetamido)-4-phenylbutanoyl)-D-leucyl-D-phenylalanine

Carfilzomib Impurity 94

CAT No: CL-CFZB-99 CAS No: 868540-15-2 Mol Wt: 629.8 Mol F: C37H47N3O6 Inv Status: Custom Synthesis

Chemical Name: Benzyl ((S)-2-((tert-butoxycarbonyl)amino)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate

Carfilzomib Impurity 95

CAT No: CL-CFZB-100 CAS No: NA Mol Wt: 629.8 Mol F: C37H47N3O6 Inv Status: Custom Synthesis

Chemical Name: Benzyl ((2S)-2-((S)-2-((tert-butoxycarbonyl)amino)-4-phenylbutanamido)-3-methylpentanoyl)-D-phenylalaninate

Carfilzomib Impurity 96

CAT No: CL-CFZB-101 CAS No: NA Mol Wt: 565.7 Mol F: C31H43N5O5 Inv Status: Custom Synthesis

Chemical Name: (S)-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 97

CAT No: CL-CFZB-102 CAS No: 3235-82-3 Mol Wt: 173.2 Mol F: C8H15NO3 Inv Status: Custom Synthesis

Chemical Name: Ethyl 2-morpholinoacetate

Carfilzomib Impurity 98

CAT No: CL-CFZB-103 CAS No: 1890999-53-7 Mol Wt: 689.9 Mol F: C39H55N5O6 Inv Status: Custom Synthesis

Chemical Name: (2S)-N-((1S)-1-(5-(1-hydroxyethyl)-4-isobutyloxazol-2-yl)-2-phenylethyl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 99

CAT No: CL-CFZB-104 CAS No: 2559766-56-0 Mol Wt: 701.9 Mol F: C40H55N5O6 Inv Status: Custom Synthesis

Chemical Name: N-(1-(2-Benzyl-5-isobutyl-2-(5-isobutyl-5-methoxy-3-methyl-4-oxo-4,5-dihydro-1H-pyrrol-2-yl)-4-oxoimidazolidin-1-yl)-1-oxo-4-phenylbutan-2-yl)-2-morpholinoacetamide

Carfilzomib Impurity 100

CAT No: CL-CFZB-105 CAS No: 2556763-77-8 Mol Wt: 703.9 Mol F: C40H57N5O6 Inv Status: Custom Synthesis

Chemical Name: N-(1-(5-Isobutyl-5-methoxy-3-methyl-4-oxo-4,5-dihydro-1H-pyrrol-2-yl)-2-phenylethyl)-4-methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 101

CAT No: CL-CFZB-106 CAS No: 2419266-61-6 Mol Wt: 566.7 Mol F: C31H42N4O6 Inv Status: Custom Synthesis

Chemical Name: ((S)-2-(2-morpholinoacetamido)-4-phenylbutanoyl)-L-leucyl-D-phenylalanine

Carfilzomib Impurity 102

CAT No: CL-CFZB-107 CAS No: NA Mol Wt: 737.9 Mol F: C40H59N5O8 Inv Status: Custom Synthesis

Chemical Name: N-(1-((1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib Impurity 103

CAT No: CL-CFZB-108 CAS No: NA Mol Wt: 735.9 Mol F: C40H57N5O8 Inv Status: Custom Synthesis

Chemical Name: 4-((4S,7S,10S,13R)-10-Benzyl-7-isobutyl-15-methyl-13-((R)-2-methyloxirane-2-carbonyl)-2,5,8,11-tetraoxo-4-phenethyl-3,6,9,12-tetraazahexadecyl)morpholine 4-oxide

Carfilzomib Impurity 104

CAT No: CL-CFZB-109 CAS No: NA Mol Wt: 737.9 Mol F: C40H59N5O8 Inv Status: Custom Synthesis

Chemical Name: N-(1-((1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Carfilzomib D8

CAT No: CL-CFZB-110 CAS No: 1537187-53-3 Mol Wt: 728 Mol F: C40H49D8N5O7 Inv Status: Custom Synthesis

Chemical Name: (S)-4-Methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-(morpholino-d8)acetamido)-4-phenylbutanamido)pentanamide

Type:Impurity Reference Standard

API NAME:Carfilzomib

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