Impurity Reference Standard - Products

Cobimetinib

CAT No: CL-CBMT-01 CAS No: 934660-93-2 Mol Wt: 531.3 Mol F: C21H21F3IN3O2 Inv Status: Custom Synthesis

Chemical Name: (S)-(3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone

Cobimetinib D9

CAT No: CL-CBMT-02 CAS No: 2714409-22-8 Mol Wt: 540.4 Mol F: C21H12D9F3IN3O2 Inv Status: Custom Synthesis

Chemical Name: (3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(piperidin-2-yl-2,3,3,4,4,5,5,6,6-d9)azetidin-1-yl)methanone

Cobimetinib Impurity 1

CAT No: CL-CBMT-03 CAS No: 1597407-56-1 Mol Wt: 376.5 Mol F: C21H32N2O4 Inv Status: Custom Synthesis

Chemical Name: Tert-butyl 3-hydroxy-3-((S)-1-((S)-2-hydroxy-1-phenylethyl)piperidin-2-yl)azetidine-1-carboxylate

Cobimetinib Impurity 2

CAT No: CL-CBMT-04 CAS No: 1597407-58-3 Mol Wt: 434.5 Mol F: C23H25F3N2O3 Inv Status: Custom Synthesis

Chemical Name: (3-Hydroxy-3-((S)-1-((S)-2-hydroxy-1-phenylethyl)piperidin-2-yl)azetidin-1-yl)(2,3,4-trifluorophenyl)methanone

Cobimetinib Impurity 3

CAT No: CL-CBMT-05 CAS No: 2065147-70-6 Mol Wt: 314.3 : 36.5 Mol F: C15H17F3N2O2 : HCl Inv Status: Custom Synthesis

Chemical Name: (S)-(3-Hydroxy-3-(piperidin-2-yl)azetidin-1-yl)(2,3,4-trifluorophenyl)methanone hydrochloride

Cobimetinib R Isomer

CAT No: CL-CBMT-06 CAS No: 934660-94-3 Mol Wt: 531.3 Mol F: C21H21F3IN3O2 Inv Status: Custom Synthesis

Chemical Name: (R)-(3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone

Cobimetinib Racemic Mixture

CAT No: CL-CBMT-07 CAS No: 934662-91-6 Mol Wt: 531.3 Mol F: C21H21F3IN3O2 Inv Status: Custom Synthesis

Chemical Name: (3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone