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Type:Impurity Reference Standard
API NAME:Methotrexate
Total Products: 52
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Methotrexate
CAT No: CL-MOXT-01 CAS No: 59-05-2 Mol Wt: 454.45 Mol F: C20H22N8O5 Inv Status: Custom Synthesis
Chemical Name: (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid
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Methotrexate EP Impurity A
CAT No: CL-MOXT-02 CAS No: 945-24-4 Mol Wt: 192.1 Mol F: C7H8N6O Inv Status: Custom Synthesis
Chemical Name: 2,4-Diamino-6-(hydroxymethyl)pteridine hydrochloride
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Methotrexate EP Impurity B
CAT No: CL-MOXT-03 CAS No: 54-62-6 Mol Wt: 440.41 Mol F: C19H20N8O5 Inv Status: Custom Synthesis
Chemical Name: (4-(((2,4-diaminopteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid
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Methotrexate EP Impurity C
CAT No: CL-MOXT-04 CAS No: 2410-93-7 Mol Wt: 455.4 Mol F: C20H21N7O6 Inv Status: Custom Synthesis
Chemical Name: (4-(((2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid
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Methotrexate EP Impurity D
CAT No: CL-MOXT-05 CAS No: 5623-18-7 Mol Wt: 326.3 Mol F: C15H14N6O3 Inv Status: Custom Synthesis
Chemical Name: 4-(((2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl)(methyl)amino)benzoic acid
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Methotrexate EP Impurity E
CAT No: CL-MOXT-06 CAS No: 19741-14-1 Mol Wt: 325.3 Mol F: C15H15N7O2 Inv Status: Custom Synthesis
Chemical Name: 4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoic acid
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Methotrexate EP Impurity F
CAT No: CL-MOXT-07 CAS No: 51865-79-3 Mol Wt: 454.4 Mol F: C20H22N8O5 Inv Status: Custom Synthesis
Chemical Name: (2R)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl] amino] pentanedioic acid
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Methotrexate EP Impurity G
CAT No: CL-MOXT-08 CAS No: NA Mol Wt: 587.6 Mol F: C28H29N9O6 Inv Status: Custom Synthesis
Chemical Name: (4-(4-(((2,4-diamino-4a,8a-dihydropteridin-6-yl)methyl)(methyl)amino)-N-methylbenzamido)benzoyl)-L-glutamic acid
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Methotrexate EP Impurity H
CAT No: CL-MOXT-09 CAS No: 67022-39-3 Mol Wt: 468.5 Mol F: C21H24N8O5 Inv Status: Custom Synthesis
Chemical Name: (2S)-2-(4-(((2,4-diamino-4a,8a-dihydropteridin-6-yl)methyl)(methyl)amino)benzamido)-5-methoxy-5-oxopentanoic acid
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Methotrexate EP Impurity I
CAT No: CL-MOXT-10 CAS No: 66147-29-3 Mol Wt: 468.5 Mol F: C21H24N8O5 Inv Status: Custom Synthesis
Chemical Name: (4S)-4-[[4-[[(2,4-diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
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Methotrexate EP Impurity J
CAT No: CL-MOXT-11 CAS No: 34378-65-9 Mol Wt: 482.5 Mol F: C22H26N8O5 Inv Status: Custom Synthesis
Chemical Name: Dimethyl (2S)-2-[[4-[[(2,4-diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]pentanedioate
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Methotrexate EP Impurity K
CAT No: CL-MOXT-12 CAS No: 4271-30-1 Mol Wt: 266.3 Mol F: C12H14N2O5 Inv Status: Custom Synthesis
Chemical Name: (4-Aminobenzoyl)-L-glutamic acid
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Methotrexate EP Impurity L
CAT No: CL-MOXT-13 CAS No: 52980-68-4 Mol Wt: 280.3 Mol F: C13H16N2O5 Inv Status: Custom Synthesis
Chemical Name: (4-(Methylamino)benzoyl)-L-glutamic acid
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Methotrexate 7-Hydroxy Metabolite
CAT No: CL-MOXT-14 CAS No: 5939-37-7 Mol Wt: 470.4 Mol F: C20H22N8O6 Inv Status: Custom Synthesis
Chemical Name: 4-Amino-7-hydroxy-10-methylpteroylglutamic acid ; (4-(((2,4-diamino-7-hydroxypteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid
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Methotrexate EP Impurity B Hydrate
CAT No: CL-MOXT-15 CAS No: 1217459-90-9 Mol Wt: 440.4 : 18.0 Mol F: C19H20N8O5 : H2O Inv Status: Custom Synthesis
Chemical Name: (2S)-2-[[4-[[(2,4-diaminopteridin-6-yl)methyl]amino]benzoyl]amino]pentanedioic acid hydrate
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(R)-Methotrexate
CAT No: CL-MOXT-16 CAS No: 51865-79-3 Mol Wt: 454.4 Mol F: C20H22N8O5 Inv Status: Custom Synthesis
Chemical Name: (R)-methotrexate
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Methotrexate Impurity
CAT No: CL-MOXT-17 CAS No: 73978-41-3 Mol Wt: 192.2 : 36.5 Mol F: C7H8N6O : HCl Inv Status: Custom Synthesis
Chemical Name: 2,4-Diamino-6-(hydroxymethyl)pteridine hydrochloride
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Methotrexate Dimethylamide
CAT No: CL-MOXT-18 CAS No: 71074-44-7 Mol Wt: 481.5 Mol F: C22H27N9O4 Inv Status: Custom Synthesis
Chemical Name: N2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-N5,N5-dimethyl-L-glutamine
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Methotrexate Dihydrate
CAT No: CL-MOXT-19 CAS No: 1212284-68-8 Mol Wt: 454.4 : 2(18.0) Mol F: C20H22N8O5 : 2(H2O) Inv Status: Custom Synthesis
Chemical Name:  (2S)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]pentanedioic acid dihydrate
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Methotrexate Impurity 1
CAT No: CL-MOXT-20 CAS No: 1029980-84-4 Mol Wt: 336.4 Mol F: C17H24N2O5 Inv Status: Custom Synthesis
Chemical Name: Diethyl (2S)-2-{[2-(methylamino)benzoyl]amino}pentanedioate
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Methotrexate Impurity 12
CAT No: CL-MOXT-21 CAS No: 881-33-4 Mol Wt: 192.2 Mol F: C7H8N6O Inv Status: Custom Synthesis
Chemical Name: (2,4-Diaminopteridin-7-yl)methanol
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Methotrexate Impurity 16
CAT No: CL-MOXT-22 CAS No: 65148-63-2 Mol Wt: 482.5 Mol F: C22H26N8O5 Inv Status: Custom Synthesis
Chemical Name: (S)-4-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-ethoxy-5-oxopentanoic acid
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Methotrexate Impurity 2
CAT No: CL-MOXT-23 CAS No: 51865-66-8 Mol Wt: 336.4 Mol F: C17H24N2O5 Inv Status: Custom Synthesis
Chemical Name: Diethyl (4-(methylamino)benzoyl)-D-glutamate
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Methotrexate Impurity 7
CAT No: CL-MOXT-24 CAS No: 57963-63-0 Mol Wt: 323.3 Mol F: C16H21NO6 Inv Status: Custom Synthesis
Chemical Name: Diethyl (4-hydroxybenzoyl)-L-glutamate
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Methotrexate Impurity 8
CAT No: CL-MOXT-25 CAS No: 909874-43-7 Mol Wt: 350.4 Mol F: C18H26N2O5 Inv Status: Custom Synthesis
Chemical Name: Diethyl (4-(dimethylamino)benzoyl)-L-glutamate
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S-methylaminobenzoyl glutamicester
CAT No: CL-MOXT-26 CAS No: 2378-95-2 Mol Wt: 336.4 Mol F: C17H24N2O5 Inv Status: Custom Synthesis
Chemical Name: Diethyl (4-(methylamino)benzoyl)-L-glutamate
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Methotrexate EP Impurity F (Sodium salt)
CAT No: CL-MOXT-27 CAS No: NA Mol Wt: 452.4 : 2(23.0) Mol F: C20H20N8O5 : 2(Na) Inv Status: Custom Synthesis
Chemical Name: Sodium (R)-2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate
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Methotrexate N-Desmethyl Impurity
CAT No: CL-MOXT-28 CAS No: 1189252-22-9 Mol Wt: 312.3 : 18.0 Mol F: C14H12N6O3 : H2O Inv Status: Custom Synthesis
Chemical Name: 4-(((2-amino-4-hydroxypteridin-6-yl)methyl)amino)benzoic acid
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Amethopterin
CAT No: CL-MOXT-29 CAS No: 60388-53-6 Mol Wt: 454.4 Mol F: C20H22N8O5 Inv Status: Custom Synthesis
Chemical Name: (4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)glutamic acid
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2,4-Diaminopteridine
CAT No: CL-MOXT-30 CAS No: 1127-93-1 Mol Wt: 162.2 Mol F: C6H6N6 Inv Status: Custom Synthesis
Chemical Name: Pteridine-2,4-diamine
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6-Methyl-2,4-pteridinediamine
CAT No: CL-MOXT-31 CAS No: 708-74-7 Mol Wt: 176.2 Mol F: C7H8N6 Inv Status: Custom Synthesis
Chemical Name: 6-Methylpteridine-2,4-diamine
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Methotrexate Diethyl Ester
CAT No: CL-MOXT-32 CAS No: 43170-88-3 Mol Wt: 510.6 Mol F: C24H30N8O5 Inv Status: Custom Synthesis
Chemical Name: Diethyl (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamate
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Methotrexate Impurity 10
CAT No: CL-MOXT-33 CAS No: NA Mol Wt: 341.8 Mol F: C16H20ClNO5 Inv Status: Custom Synthesis
Chemical Name: Diethyl (4-chlorobenzoyl)-L-glutamate
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Methotrexate Impurity 11
CAT No: CL-MOXT-34 CAS No: 34794-87-1 Mol Wt: 326.3 Mol F: C15H14N6O3 Inv Status: Custom Synthesis
Chemical Name: Methyl 4-(((2-amino-4-oxo-4,8-dihydropteridin-6-yl)methyl)amino)benzoate
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Methotrexate Impurity 13
CAT No: CL-MOXT-35 CAS No: NA Mol Wt: 308.3 Mol F: C15H20N2O5 Inv Status: Custom Synthesis
Chemical Name: (S)-5-Ethoxy-2-(4-(methylamino)benzamido)-5-oxopentanoic acid
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Methotrexate Impurity 14
CAT No: CL-MOXT-36 CAS No: NA Mol Wt: 308.3 Mol F: C15H20N2O5 Inv Status: Custom Synthesis
Chemical Name: (S)-5-ethoxy-4-(4-(methylamino)benzamido)-5-oxopentanoic acid
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Methotrexate Impurity 15
CAT No: CL-MOXT-37 CAS No: 65148-64-3 Mol Wt: 482.5 Mol F: C22H26N8O5 Inv Status: Custom Synthesis
Chemical Name: (S)-2-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-ethoxy-5-oxopentanoic acid
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Methotrexate Impurity 17
CAT No: CL-MOXT-38 CAS No: 2820151-35-5 Mol Wt: 336.4 Mol F: C17H24N2O5 Inv Status: Custom Synthesis
Chemical Name: Diethyl (3-(methylamino)benzoyl)-L-glutamate
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Methotrexate Impurity 18
CAT No: CL-MOXT-39 CAS No: NA Mol Wt: 496.5 Mol F: C23H28N8O5 Inv Status: Custom Synthesis
Chemical Name: (S)-1-ethyl 5-methyl 2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate
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Methotrexate Impurity 19
CAT No: CL-MOXT-40 CAS No: NA Mol Wt: 496.5 Mol F: C23H28N8O5 Inv Status: Custom Synthesis
Chemical Name: (S)-5-ethyl 1-methyl 2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate
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Methotrexate Impurity 3
CAT No: CL-MOXT-41 CAS No: NA Mol Wt: 469.5 Mol F: C25H31N3O6 Inv Status: Custom Synthesis
Chemical Name: Diethyl (4-(N-methyl-4-(methylamino)benzamido)benzoyl)-L-glutamate
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Methotrexate Impurity 4
CAT No: CL-MOXT-42 CAS No: 52030-86-1 Mol Wt: 280.3 Mol F: C13H16N2O5 Inv Status: Custom Synthesis
Chemical Name: (4-(Methylamino)benzoyl)-D-glutamic acid
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Methotrexate Impurity 5
CAT No: CL-MOXT-43 CAS No: 4215-07-0 Mol Wt: 176.2 Mol F: C7H8N6 Inv Status: Custom Synthesis
Chemical Name: 7-Methylpteridine-2,4-diamine
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Methotrexate Impurity 6
CAT No: CL-MOXT-44 CAS No: NA Mol Wt: 222.2 Mol F: C8H10N6O2 Inv Status: Custom Synthesis
Chemical Name: (2,4-diaminopteridine-6,7-diyl)dimethanol
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Methotrexate Impurity 9
CAT No: CL-MOXT-45 CAS No: 10541-83-0 Mol Wt: 151.2 Mol F: C8H9NO2 Inv Status: Custom Synthesis
Chemical Name: 4-(Methylamino)benzoic acid
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N-(4-chlorobenzoyl)-L-glutamic acid
CAT No: CL-MOXT-46 CAS No: 57444-70-9 Mol Wt: 285.7 Mol F: C12H12ClNO5 Inv Status: Custom Synthesis
Chemical Name: (4-Chlorobenzoyl)-L-glutamic acid
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N-(4-hydroxybenzoyl)-L-Glutamic acid
CAT No: CL-MOXT-47 CAS No: 119843-02-6 Mol Wt: 267.2 Mol F: C12H13NO6 Inv Status: Custom Synthesis
Chemical Name: (4-Hydroxybenzoyl)-L-glutamic acid
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Methotrexate D3
CAT No: CL-MOXT-48 CAS No: 432545-63-6 Mol Wt: 457.5 Mol F: C20H19D3N8O5 Inv Status: Custom Synthesis
Chemical Name: (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl-d3)amino)benzoyl)-L-glutamic acid
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Methotrexate Impurity 20 (Sulfate salt)
CAT No: CL-MOXT-49 CAS No: 5392-28-9 Mol Wt: 140.2 : 98.1 Mol F: C4H8N6 : H2SO4 Inv Status: Custom Synthesis
Chemical Name: Pyrimidine-2,4,5,6-tetraamine sulfate
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Methotrexate Impurity 21
CAT No: CL-MOXT-50 CAS No: 82778-10-7 Mol Wt: 336.4 Mol F: C17H24N2O5 Inv Status: Custom Synthesis
Chemical Name: Diethyl (4-(methylamino)benzoyl)glutamate
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Methotrexate Impurity 22
CAT No: CL-MOXT-51 CAS No: 13726-52-8 Mol Wt: 322.4 Mol F: C16H22N2O5 Inv Status: Custom Synthesis
Chemical Name: Diethyl (4-aminobenzoyl)-L-glutamate
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Methotrexate-13C,D3
CAT No: CL-MOXT-52 CAS No: NA Mol Wt: 458.5 Mol F: C1913CH19D3N8O5 Inv Status: Custom Synthesis
Chemical Name: (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl-13C-d3)amino)benzoyl)-L-glutamic acid

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