Impurity Reference Standard - Products

Paliperidone

CAT No: CL-PLP-01 CAS No: 144598-75-4 Mol Wt: 426.2 Mol F: C23H27FN4O3 Inv Status: Custom Synthesis

Chemical Name: (?)-3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone USP RC A

CAT No: CL-PLP-02 CAS No: 849903-79-3 Mol Wt: 208.3 Mol F: C11H16N2O2 Inv Status: In Stock

Chemical Name: 3-Ethyl-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido [1,2-a]pyrimidin-4-one hydrochloride

Paliperidone USP RC B

CAT No: CL-PLP-03 CAS No: 84163-77-9 Mol Wt: 220.2 Mol F: C12H13FN2O Inv Status: In Stock

Chemical Name: 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole

Paliperidone USP RC C

CAT No: CL-PLP-04 CAS No: 130049-82-0 Mol Wt: 242.7 Mol F: C11H15ClN2O2 Inv Status: In Stock

Chemical Name: 3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido-(1,2-a)-pyrimidin-4-one

Paliperidone USP RC D

CAT No: CL-PLP-05 CAS No: 761460-08-6 Mol Wt: 442.5 Mol F: C23H27FN4O4 Inv Status: In Stock

Chemical Name: 3-{2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl) piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one N-oxide

Paliperidone Z-Oxime

CAT No: CL-PLP-06 CAS No: 1388021-47-3 Mol Wt: 446.5 Mol F: C23H28F2N4O3 Inv Status: Custom Synthesis

Chemical Name: 3-[2-[4-[(Z)-(2,4-Difluorophenyl)(hydroxyimino) methyl]piperidin-1-yl]ethyl]-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone 5-Fluoro Isomer

CAT No: CL-PLP-07 CAS No: 1346598-34-2 Mol Wt: 426.2 Mol F: C23H27FN4O3 Inv Status: In Stock

Chemical Name: 3-[2-[4-(5-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone 9-Keto Impurity

CAT No: CL-PLP-08 CAS No: 1189516-65-1 Mol Wt: 424.5 Mol F: C23H25FN4O3 Inv Status: In Stock

Chemical Name: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione

Paliperidone Desfluoro Impurity

CAT No: CL-PLP-09 CAS No: 1380413-60-4 Mol Wt: 408.5 Mol F: C23H28N4O3 Inv Status: Custom Synthesis

Chemical Name: 3-[2-[4-(1,2-Benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone R-Isomer

CAT No: CL-PLP-11 CAS No: 130049-85-3 Mol Wt: 426.5 Mol F: C23H27FN4O3 Inv Status: Custom Synthesis

Chemical Name: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9(R)-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone S-Isomer

CAT No: CL-PLP-12 CAS No: 147663-01-2 Mol Wt: 426.5 Mol F: C23H27FN4O3 Inv Status: Custom Synthesis

Chemical Name: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9(S)-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone Tetradehydro Impurity

CAT No: CL-PLP-13 CAS No: 766485-15-8 Mol Wt: 422.4 Mol F: C23H23FN4O3 Inv Status: In Stock

Chemical Name: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone Palmitate

CAT No: CL-PLP-14 CAS No: 199739-10-1 Mol Wt: 664.9 Mol F: C39H57FN4O4 Inv Status: Custom Synthesis

Chemical Name: Hexadecanoic acid, 3-?[2-?[4-?(6-?fluoro-?1,?2-?benzisoxazol-?3-?yl)?-?1-?piperidinyl]?ethyl]?-?6,?7,?8,?9-?tetrahydro-?2-?methyl-?4-?oxo-?4H-?pyrido[1,?2-?a]?pyrimidin-?9-?yl ester; 9-Hydroxyrisperidone palmitate ; Invega Sustenna ; Paliperidone palmitate

Paliperidone Impurity D

CAT No: CL-PLP-15 CAS No: 1006685-69-3 Mol Wt: 470.5 Mol F: C24H27FN4O5 Inv Status: Custom Synthesis

Chemical Name: 2-(9-hydroxy-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-3-yl)ethyl 4-(6-fluorobenzo[d]isoxazol-3-yl)piperidine-1-carboxylate

Paliperidone Impurity J

CAT No: CL-PLP-17 CAS No: 2379324-96-4 Mol Wt: 631.7 Mol F: C35H39F2N5O4 Inv Status: In Stock

Chemical Name: 3-(2-(4-(4-fluoro-2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)benzoyl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone Impurity K

CAT No: CL-PLP-18 CAS No: NA Mol Wt: 646.7 Mol F: C35H40F2N6O4 Inv Status: Custom Synthesis

Chemical Name: (E)-3-(2-(4-((4-fluoro-2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)phenyl)(hydroxyimino)methyl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone Impurity M

CAT No: CL-PLP-19 CAS No: NA Mol Wt: 440.5 Mol F: C24H29FN4O3 Inv Status: In Stock

Chemical Name: 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2,6-dimethyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one; (Mixture of Diastereomers)

Paliperidone Tetradehydro Chloroethyl Impurity

CAT No: CL-PLP-20 CAS No: 260273-82-3 Mol Wt: 238.6 Mol F: C11H11ClN2O2 Inv Status: In Stock

Chemical Name: 3-(2-Chloro ethyl )-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone 2-Hydroxybenzoyl Impurity

CAT No: CL-PLP-21 CAS No: 152542-03-5 Mol Wt: 429.5 Mol F: C23H28FN3O4 Inv Status: Custom Synthesis

Chemical Name: 3-[2-[4-(4-Fluoro-2-hydroxybenzoyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (as per USP) ;Paliperidone Impurity 4

Paliperidone Impurity 5

CAT No: CL-PLP-23 CAS No: 1138463-56-5 Mol Wt: 240.7 Mol F: C11H13ClN2O2 Inv Status: In Stock

Chemical Name: 3-(2-Chloroethyl)-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione

Paliperidone Impurity 6

CAT No: CL-PLP-24 CAS No: 1268058-08-7 Mol Wt: 412.4 Mol F: C22H25FN4O3 Inv Status: Custom Synthesis

Chemical Name: 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone Impurity 7

CAT No: CL-PLP-25 CAS No: 1415488-05-9 Mol Wt: 481.1 Mol F: C27H45ClN2O3 Inv Status: Custom Synthesis

Chemical Name: Hexadecanoic acid, 3-?(2-?chloroethyl)?-?6,?7,?8,?9-?tetrahydro-?2-?methyl-?4-?oxo-?4H-?pyrido[1,?2-?a]?pyrimidin-?9-?yl ester

Paliperidone Impurity 8

CAT No: CL-PLP-26 CAS No: 2985926-12-1 Mol Wt: 646.9 Mol F: C39H58N4O4 Inv Status: Custom Synthesis

Chemical Name: 3-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl palmitate

Paliperidone Impurity 9

CAT No: CL-PLP-27 CAS No: NA Mol Wt: 257.1 Mol F: C11H10Cl2N2O Inv Status: Custom Synthesis

Chemical Name: 9-chloro-3-(2-chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone Impurity 10

CAT No: CL-PLP-28 CAS No: 1008796-23-3 Mol Wt: 206.2 Mol F: C11H14N2O2 Inv Status: Custom Synthesis

Chemical Name: 4H-?Pyrido[1,?2-?a]?pyrimidin-?4-?one, 3-?ethenyl-?6,?7,?8,?9-?tetrahydro-?9-?hydroxy-?2-?methyl-; 3-Vinyl-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone Impurity 11

CAT No: CL-PLP-29 CAS No: 150332-87-9 Mol Wt: 278.3 Mol F: C15H19FN2O2 Inv Status: Custom Synthesis

Chemical Name: 3-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)propan-1-ol

Paliperidone Impurity 12

CAT No: CL-PLP-30 CAS No: 1404053-61-7 Mol Wt: 650.9 Mol F: C38H55FN4O4 Inv Status: In Stock

Chemical Name: 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl pentadecanoate

Paliperidone Impurity 13

CAT No: CL-PLP-31 CAS No: 1404053-62-8 Mol Wt: 678.9 Mol F: C40H59FN4O4 Inv Status: In Stock

Chemical Name: 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl heptadecanoate

Paliperidone N-1 Intermediate

CAT No: CL-PLP-32 CAS No: 147687-17-0 Mol Wt: 328.8 Mol F: C18H17ClN2O2 Inv Status: Custom Synthesis

Chemical Name: 9-(benzyloxy)-3-(2-chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone Intermediate -I Of KSM-I

CAT No: CL-PLP-33 CAS No: 1008796-22-2 Mol Wt: 310.4 Mol F: C18H18N2O3 Inv Status: Custom Synthesis

Chemical Name: 9-(benzyloxy)-3-(2-hydroxyethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

N-formyl Isonipecotic acid

CAT No: CL-PLP-34 CAS No: 498-94-2 Mol Wt: 129.2 Mol F: C6H11NO2 Inv Status: In Stock

Chemical Name: Piperidine-4-carboxylic acid

Paliperidone E-Oxime

CAT No: CL-PLP-35 CAS No: 1388021-46-2 Mol Wt: 446.5 Mol F: C23H28F2N4O3 Inv Status: In Stock

Chemical Name: 3-[2-[4-[(E)-(2,4-Difluorophenyl)(hydroxyimino) methyl]piperidin-1-yl]ethyl]-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

Hydroxybenzoyl Paliperidone

CAT No: CL-PLP-36 CAS No: 152542-03-5 Mol Wt: 429.5 Mol F: C23H28FN3O4 Inv Status: In Stock

Chemical Name: 3-[2-[4-(4-Fluoro-2-hydroxybenzoyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone Impurity 2

CAT No: CL-PLP-37 CAS No: NA Mol Wt: 284.74 Mol F: C13H17ClN2O3 Inv Status: In Stock

Chemical Name: 3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl acetate

Paliperidone Impurity 1

CAT No: CL-PLP-38 CAS No: 147687-17-0 Mol Wt: 328.8 Mol F: C18H17ClN2O2 Inv Status: In Stock

Chemical Name: 9-(benzyloxy)-3-(2-chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Paliperidone Impurity 4

CAT No: CL-PLP-39 CAS No: NA Mol Wt: 420.49 Mol F: C24H25FN4O2 Inv Status: In Stock

Chemical Name: 6-fluoro-3-(1-(3-(piperidin-4-yl)benzo[d]isoxazol-6-yl)piperidin-4-yl)benzo[d]isoxazole

Paliperidone Palmitate N-Oxide

CAT No: CL-PLP-40 CAS No: 1404053-60-6 Mol Wt: 680.9 Mol F: C39H57FN4O5 Inv Status: In Stock

Chemical Name: 4-(6-fluorobenzo[d]isoxazol-3-yl)-1-(2-(2-methyl-4-oxo-9-(palmitoyloxy)-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-3-yl)ethyl)piperidine 1-oxide

Paliperidone Related Compound B

CAT No: CL-PLP-41 CAS No: 84163-13-3 Mol Wt: 220.2 : 36.5 Mol F: C12H13FN2O : HCl Inv Status: In Stock

Chemical Name: 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride

Paliperidone Impurity B

CAT No: CL-PLP-42 CAS No: 1172995-13-9 Mol Wt: 693 Mol F: C41H61FN4O4 Inv Status: In Stock

Chemical Name: 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl stearate

Paliperidone Impurity A

CAT No: CL-PLP-43 CAS No: 1172995-11-7 Mol Wt: 636.9 Mol F: C37H53FN4O4 Inv Status: In Stock

Chemical Name: 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl tetradecanoate

Type:Impurity Reference Standard

API NAME:Paliperidone

Total Products: 40

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