Impurity Reference Standard - Products

Pemetrexed

CAT No: CL-PMT-01 CAS No: 137281-23-3 Mol Wt: 427.4 Mol F: C20H21N5O6 Inv Status: Custom Synthesis

Chemical Name: (4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid

Pemetrexed EP Impurity A

CAT No: CL-PMT-02 CAS No: 869791-42-4 Mol Wt: 441.4 Mol F: C21H23N5O6 Inv Status: Custom Synthesis

Chemical Name: (2S)-2-[4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]pentanedioic acid ; {4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-l-glutamic acid (as per USP)

Pemetrexed EP Impurity B

CAT No: CL-PMT-03 CAS No: 1802552-04-0 Mol Wt: 868.8 Mol F: C40H40N10O13 Inv Status: Custom Synthesis

Chemical Name: (2S,2'S)-2,2'-[(45R)-42,52-Diamino-44,46,54-trioxo-41,44,46,47,54,57-hexahydro-45H,51H-4(5,5),5(6,5)-dipyrrolo[2,3-d]pyrimidina-1,8(1)-dibenzenaoctaphane-14,84-dicarboxamido]dipentanedioic acid

Pemetrexed EP Impurity C

CAT No: CL-PMT-04 CAS No: 1802552-16-4 Mol Wt: 868.8 Mol F: C40H40N10O13 Inv Status: Custom Synthesis

Chemical Name: (2S,2'S)-2,2'-[(45S)-42,52-Diamino-44,46,54-trioxo-41,44,46,47,54,57-hexahydro-45H,51H-4(5,5),5(6,5)-dipyrrolo[2,3-d]pyrimidina-1,8(1)-dibenzenaoctaphane-14,84-dicarboxamido]dipentanedioic acid

Pemetrexed EP Impurity D

CAT No: CL-PMT-05 CAS No: 144051-68-3 Mol Wt: 556.5 Mol F: C25H28N6O9 Inv Status: Custom Synthesis

Chemical Name: (2S)-2-[(4S)-4-[4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]-4-carboxybutanamido]pentanedioic acid ; {4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-4-l-glutamyl-l-glutamic acid (as per USP)

Pemetrexed EP Impurity E

CAT No: CL-PMT-06 CAS No: 182009-04-7 Mol Wt: 427.4 Mol F: C20H21N5O6 Inv Status: Custom Synthesis

Chemical Name: (2R)-2-[4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]pentanedioic acid

Pemetrexed Keto Impurity

CAT No: CL-PMT-07 CAS No: 193281-00-4 Mol Wt: 443.4 Mol F: C20H21N5O7 Inv Status: Custom Synthesis

Chemical Name: (4-(2-(2-Amino-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid

Pemetrexed Impurity 16

CAT No: CL-PMT-08 CAS No: 193265-47-3 Mol Wt: 314.3 Mol F: C15H14N4O4 Inv Status: Custom Synthesis

Chemical Name: 4-(2-(2-Amino-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoic acid

Pemetrexed Glutamide Impurity

CAT No: CL-PMT-09 CAS No: NA Mol Wt: 570.6 Mol F: C26H30N6O9 Inv Status: Custom Synthesis

Chemical Name: ((S)-4-(4-(2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-4-carboxybutanoyl)-L-glutamic acid

Pemetrexed Impurity 1

CAT No: CL-PMT-10 CAS No: 1265908-64-2 Mol Wt: 441.4 Mol F: C21H23N5O6 Inv Status: Custom Synthesis

Chemical Name: (S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoic acid

Pemetrexed Impurity 2

CAT No: CL-PMT-11 CAS No: 155405-80-4 Mol Wt: 312.3 Mol F: C16H16N4O3 Inv Status: Custom Synthesis

Chemical Name: Methyl 4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate

Pemetrexed Impurity 3

CAT No: CL-PMT-12 CAS No: 1265908-63-1 Mol Wt: 441.4 Mol F: C21H23N5O6 Inv Status: Custom Synthesis

Chemical Name: (S)-4-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoic acid

Pemetrexed Impurity 18

CAT No: CL-PMT-13 CAS No: 155405-81-5 Mol Wt: 455.5 Mol F: C22H25N5O6 Inv Status: Custom Synthesis

Chemical Name: Dimethyl (4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate

Pemetrexed Impurity 19

CAT No: CL-PMT-14 CAS No: 193281-05-9 Mol Wt: 431.4 Mol F: C19H21N5O7 Inv Status: Custom Synthesis

Chemical Name: (4-(3-(2,6-Diamino-4-oxo-1,4-dihydropyrimidin-5-yl)-3-oxopropyl)benzoyl)-L-glutamic acid

Pemetrexed Impurity 20

CAT No: CL-PMT-15 CAS No: NA Mol Wt: 556.5 Mol F: C25H28N6O9 Inv Status: Custom Synthesis

Chemical Name: (4-(2-(2-((S)-4-Amino-4-carboxybutanamido)-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid

Pemetrexed Mixture Of Impurity B & C

CAT No: CL-PMT-16 CAS No: 1644286-34-9 Mol Wt: 868.8 Mol F: C40H40N10O13 Inv Status: Custom Synthesis

Chemical Name: (2S,2'S)-2,2'-((4,4'-((2,2'-Diamino-4,4',6-trioxo-1,4,4',6,7,7'-hexahydro-1'H,5H-[5,6'-bipyrrolo[2,3-d]pyrimidine]-5,5'-diyl)bis(ethane-2,1-diyl))bis(benzoyl))bis(azanediyl))diglutaric acid

Pemetrexed Alpha-Hydroxy Lactum

CAT No: CL-PMT-17 CAS No: 1644286-36-1 Mol Wt: 459.4 Mol F: C20H21N5O8 Inv Status: Custom Synthesis

Chemical Name: (4-(2-(2-Amino-5-hydroxy-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid

Pemetrexed Opened Ring Keto-Formamide

CAT No: CL-PMT-18 CAS No: 1644286-35-0 Mol Wt: 459.4 Mol F: C20H21N5O8 Inv Status: Custom Synthesis

Chemical Name: (4-(3-(2-Amino-6-formamido-4-oxo-1,4-dihydropyrimidin-5-yl)-3-oxopropyl)benzoyl)-D-glutamic acid

Pemetrexed Impurity 21

CAT No: CL-PMT-19 CAS No: NA Mol Wt: 942.9 Mol F: C43H46N10O15 Inv Status: Custom Synthesis

Chemical Name: (4-(2-(2,2'-Diamino-5-(4-((1-carboxy-4-(2-carboxyethoxy)-4-oxobutyl)carbamoyl)phenethyl)-6-hydroxy-4,4'-dioxo-4,4',5,6,7,7'-hexahydro-3H,3'H-[5,6'-bipyrrolo[2,3-d]pyrimidin]-5'-yl)ethyl)benzoyl)glutamic acid

Pemetrexed Impurity 22

CAT No: CL-PMT-20 CAS No: NA Mol Wt: 626.7 Mol F: C30H38N6O9 Inv Status: Custom Synthesis

Chemical Name: Diethyl (4-(2-(2-((S)-2-amino-5-methoxy-5-oxopentanamido)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate

Pemetrexed Epoxy Hemiaminal

CAT No: CL-PMT-21 CAS No: NA Mol Wt: 461.4 Mol F: C20H23N5O8 Inv Status: Custom Synthesis

Chemical Name: (4-(2-(2-Amino-7-hydroxy-4-oxo-4,4a,6,7-tetrahydro-3H-pyrimido[5,4-b][1,4]oxazin-6-yl)ethyl)benzoyl)-L-glutamic acid

Pemetrexed Opened Ring Keto Amide

CAT No: CL-PMT-22 CAS No: NA Mol Wt: 430.4 Mol F: C20H22N4O7 Inv Status: Custom Synthesis

Chemical Name: (4-(3-(4,6-Diamino-2-oxo-1,2-dihydropyridin-3-yl)-3-oxopropyl)benzoyl)-L-glutamic acid

Type:Impurity Reference Standard

API NAME:Pemetrexed

Total Products: 22

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