Impurity Reference Standard - Products

Rilpivirine

CAT No: CL-RIL-01 CAS No: 500287-72-9 Mol Wt: 366.4 Mol F: C22H18N6 Inv Status: Custom Synthesis

Chemical Name: (E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile

Rilpivirine (E)-Nitrile Impurity

CAT No: CL-RIL-02 CAS No: 500292-94-4 Mol Wt: 172.2 Mol F: C11H12N2 Inv Status: Custom Synthesis

Chemical Name: (E)-3-(4-amino-3,5-dimethylphenyl)acrylonitrile

Rilpivirine (Z)-Nitrile Impurity

CAT No: CL-RIL-03 CAS No: 661489-22-1 Mol Wt: 172.2 Mol F: C11H12N2 Inv Status: Custom Synthesis

Chemical Name: (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile ; (2Z)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile

Rilpivirine Chloro Impurity

CAT No: CL-RIL-04 CAS No: 244768-32-9 Mol Wt: 230.7 Mol F: C11H7ClN4 Inv Status: Custom Synthesis

Chemical Name: 4-[(4-Chloropyrimidin-2-yl)amino]-Benzonitrile

Rilpivirine Keto Impurity

CAT No: CL-RIL-05 CAS No: 189956-45-4 Mol Wt: 212.2 Mol F: C11H8N4O Inv Status: Custom Synthesis

Chemical Name: 4-((6-Oxo-1,6-dihydropyrimidin-2-yl)amino)benzonitrile

Rilpivirine N-Oxide

CAT No: CL-RIL-06 CAS No: 2734549-19-8 Mol Wt: 382.4 Mol F: 2734549-19-8 Inv Status: Custom Synthesis

Chemical Name: (E)-2-((4-cyanophenyl)amino)-4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidine 1-oxide

Rilpivirine Z-Isomer

CAT No: CL-RIL-07 CAS No: 500287-94-5 Mol Wt: 366.4 Mol F: C22H18N6 Inv Status: Custom Synthesis

Chemical Name: 4-[[4-[[4-[(1Z)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]-benzonitrile

Rilpivirine E-Z mixture Isomer

CAT No: CL-RIL-08 CAS No: 620622-82-4 Mol Wt: 366.4 Mol F: C22H18N6 Inv Status: Custom Synthesis

Chemical Name: 4-[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile

2-Hydroxymethyl Rilpivirine

CAT No: CL-RIL-09 CAS No: 1798429-64-7 Mol Wt: 382.4 Mol F: C22H18N6O Inv Status: Custom Synthesis

Chemical Name: 4-((4-((4-(2-Cyanovinyl)-2-(hydroxymethyl)-6-methylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile

Rilpivirine ADPA Impurity

CAT No: CL-RIL-10 CAS No: 500292-90-0 Mol Wt: 172.2 : 36.5 Mol F: C11H12N2 : HCl Inv Status: Custom Synthesis

Chemical Name: (E)-3-(4-amino-3,5-dimethylphenyl)acrylonitrile hydrochloride

Rilpivirine Dimethyl Phenyl Impurity

CAT No: CL-RIL-11 CAS No: 244768-59-0 Mol Wt: 315.4 Mol F: C19H17N5 Inv Status: Custom Synthesis

Chemical Name: 4-((4-((2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile

Rilpivirine Dipyrimidinyl Impurity

CAT No: CL-RIL-12 CAS No: NA Mol Wt: 560.6 Mol F: C33H24N10 Inv Status: Custom Synthesis

Chemical Name: (E)-4-((4-((4-cyanophenyl)(4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)pyrimidin-2-yl)amino)benzonitrile

Rilpivirine Glycosamine and Amadori Rearrangement product-I

CAT No: CL-RIL-13 CAS No: NA Mol Wt: 690.7 Mol F: C34H38N6O10 Inv Status: Custom Synthesis

Chemical Name: (E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)(3,5,6-trihydroxy-2-oxo-4-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexyl)amino)pyrimidin-2-yl)amino)benzonitrile

Rilpivirine Glycosamine and Amadori Rearrangement product-II

CAT No: CL-RIL-14 CAS No: NA Mol Wt: 690.7 Mol F: C34H38N6O10 Inv Status: Custom Synthesis

Chemical Name: (E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(3,5,6-trihydroxy-2-oxo-4-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexyl)amino)benzonitrile

Rilpivirine Iodo Impurity

CAT No: CL-RIL-15 CAS No: 661489-24-3 Mol Wt: 441.3 Mol F: C19H16IN5 Inv Status: Custom Synthesis

Chemical Name: 4-((4-((4-iodo-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile

Rilpivirine Methyl ester impurity

CAT No: CL-RIL-16 CAS No: NA Mol Wt: 399.5 Mol F: C23H21N5O2 Inv Status: Custom Synthesis

Chemical Name: Methyl (E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzoate

Rilpivirine N-Glucuronide

CAT No: CL-RIL-17 CAS No: 1437791-52-0 Mol Wt: 542.6 Mol F: C28H26N6O6 Inv Status: Custom Synthesis

Chemical Name: 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile N-Glucuronide

Rilpivirine Amide Impurity 1

CAT No: CL-RIL-18 CAS No: 500288-66-4 Mol Wt: 384.4 Mol F: C22H20N6O Inv Status: Custom Synthesis

Chemical Name: (2E)-3-[4-[[2[(4-Cyanophenyl)amino]pyrimidin-4-yl]amino]-3, 5-Dimethylphenyl]prop-2-Enamid

Rilpivirine Amide Impurity 2

CAT No: CL-RIL-19 CAS No: 1446439-51-5 Mol Wt: 384.4 Mol F: C22H20N6O Inv Status: Custom Synthesis

Chemical Name: 4-{[4-({4-(E)-2-Cyanoethyl]-2, 6-Dimethyl]phenyl}amino-2-Pyrimidinyl]amino}-Benzamide

Rilpivirine (E)-Nitrile Impurity (HCl salt)

CAT No: CL-RIL-20 CAS No: 661489-23-2 Mol Wt: 172.2 : 36.5 Mol F: C11H12N2 : HCl Inv Status: Custom Synthesis

Chemical Name: (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile hydrochloride

Rilpivirine Impurity 11

CAT No: CL-RIL-21 CAS No: NA Mol Wt: 385.4 Mol F: C22H19N5O2 Inv Status: Custom Synthesis

Chemical Name: (E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzoic acid

Rilpivirine Hydrochloride

CAT No: CL-RIL-23 CAS No: 700361-47-3 Mol Wt: 366.4 : 36.5 Mol F: C22H18N6 : HCl Inv Status: Custom Synthesis

Chemical Name: 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile hydrochloride

Rilpivirine Impurity 1

CAT No: CL-RIL-24 CAS No: 1629023-90-0 Mol Wt: 312.3 Mol F: C18H12N6 Inv Status: Custom Synthesis

Chemical Name: 4,4'-(pyrimidine-2,4-diylbis(azanediyl))dibenzonitrile

Rilpivirine Impurity 10

CAT No: CL-RIL-25 CAS No: NA Mol Wt: 628.7 Mol F: C38H32N10 Inv Status: Custom Synthesis

Chemical Name: 4,4'-((((3,3',5,5'-tetramethyl-[1,1'-biphenyl]-4,4'-diyl)bis(azanediyl))bis(pyrimidine-4,2-diyl))bis(azanediyl))dibenzonitrile

Rilpivirine Impurity 12

CAT No: CL-RIL-26 CAS No: 1862191-58-9 Mol Wt: 158.2 Mol F: C10H10N2 Inv Status: Custom Synthesis

Chemical Name: (E)-3-(4-amino-3-methylphenyl)acrylonitrile

Rilpivirine Impurity 13

CAT No: CL-RIL-27 CAS No: 4102-53-8 Mol Wt: 247.1 Mol F: C8H10IN Inv Status: Custom Synthesis

Chemical Name: 4-Iodo-2,6-dimethylaniline

Rilpivirine Impurity 9

CAT No: CL-RIL-28 CAS No: 1446690-23-8 Mol Wt: 402.5 Mol F: C22H22N6O2 Inv Status: Custom Synthesis

Chemical Name: (E)-4-((4-((4-(3-amino-3-oxoprop-1-en-1-yl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzamide

Rilpivirine Impurity 2

CAT No: CL-RIL-29 CAS No: NA Mol Wt: 380.5 Mol F: C23H20N6 Inv Status: Custom Synthesis

Chemical Name: (Z)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)(methyl)amino)pyrimidin-2-yl)amino)benzonitrile

Rilpivirine Impurity 3

CAT No: CL-RIL-30 CAS No: NA Mol Wt: 380.5 Mol F: C23H20N6 Inv Status: Custom Synthesis

Chemical Name: (Z)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(methyl)amino)benzonitrile

Rilpivirine Impurity 4

CAT No: CL-RIL-31 CAS No: NA Mol Wt: 380.5 Mol F: C23H20N6 Inv Status: Custom Synthesis

Chemical Name: (E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)(methyl)amino)pyrimidin-2-yl)amino)benzonitrile

Rilpivirine Impurity 5

CAT No: CL-RIL-32 CAS No: NA Mol Wt: 380.5 Mol F: C23H20N6 Inv Status: Custom Synthesis

Chemical Name: (E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(methyl)amino)benzonitrile

Rilpivirine Impurity 7

CAT No: CL-RIL-33 CAS No: NA Mol Wt: 186.3 Mol F: C12H14N2 Inv Status: Custom Synthesis

Chemical Name: (E)-3-(3,5-dimethyl-4-(methylamino)phenyl)acrylonitrile

Rilpivirine Impurity 8

CAT No: CL-RIL-34 CAS No: NA Mol Wt: 732.9 Mol F: C44H36N12 Inv Status: Custom Synthesis

Chemical Name: (Z)-2-(4-((4-((4-cyanophenyl)amino)pyrimidin-2-yl)amino)-3,5-dimethylbenzylidene)-3-(4-((4-((4-cyanophenyl)amino)pyrimidin-2-yl)amino)-3,5-dimethylphenyl)pentanedinitrile

Rilpivirine D6

CAT No: CL-RIL-35 CAS No: 1312424-26-2 Mol Wt: 372.5 Mol F: C22H12D6N6 Inv Status: Custom Synthesis

Chemical Name: (E)-4-((4-((4-(2-cyanovinyl)-2,6-bis(methyl-d3)phenyl)amino)pyrimidin-2-yl)amino)benzonitrile

Type:Impurity Reference Standard

API NAME:Rilpivirine

Total Products: 34

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