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Type:Impurity Reference Standard
API NAME:Riociguat
Total Products: 50
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Riociguat
CAT No: CL-RCG-01 CAS No: 625115-55-1 Mol Wt: 422.4 Mol F: C20H19FN8O2 Inv Status: Custom Synthesis
Chemical Name: Methyl (4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl)carbamate
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Riociguat Impurity 1
CAT No: CL-RCG-02 CAS No: NA Mol Wt: 436.5 Mol F: C21H21FN8O2 Inv Status: Custom Synthesis
Chemical Name: Methyl (4-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-(methylamino)pyrimidin-5-yl)(methyl)carbamate
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Riociguat Impurity 2
CAT No: CL-RCG-03 CAS No: 304874-06-4 Mol Wt: 284.3 Mol F: C15H13FN4O Inv Status: Custom Synthesis
Chemical Name: Methyl 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbimidate
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Riociguat Impurity 3
CAT No: CL-RCG-04 CAS No: NA Mol Wt: 441.5 Mol F: C23H20FN9 Inv Status: Custom Synthesis
Chemical Name: 2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(2-phenylhydrazinyl)pyrimidine-4,6-diamine
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Riociguat Impurity 4
CAT No: CL-RCG-05 CAS No: NA Mol Wt: 466.4 Mol F: C21H19FN8O4 Inv Status: Custom Synthesis
Chemical Name: Dimethyl (6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5-diyl)dicarbamate
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Riociguat Impurity 5
CAT No: CL-RCG-06 CAS No: 2514697-53-9 Mol Wt: 422.4 Mol F: C20H19FN8O2 Inv Status: Custom Synthesis
Chemical Name: Methyl (4-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-(methylamino)pyrimidin-5-yl)carbamate
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Riociguat Impurity 6
CAT No: CL-RCG-07 CAS No: 1702271-98-4 Mol Wt: 364.4 Mol F: C18H17FN8 Inv Status: Custom Synthesis
Chemical Name: 2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-N5-methylpyrimidine-4,5,6-triamine
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Riociguat Impurity 7
CAT No: CL-RCG-08 CAS No: 2518331-19-4 Mol Wt: 480.5 Mol F: C22H21FN8O4 Inv Status: Custom Synthesis
Chemical Name: Methyl (4-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-((methoxycarbonyl)amino)pyrimidin-5-yl)(methyl)carbamate
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Riociguat Impurity 8
CAT No: CL-RCG-09 CAS No: NA Mol Wt: 422.4 Mol F: C20H19FN8O2 Inv Status: Custom Synthesis
Chemical Name: Methyl (4,6-diamino-2-(1-(3-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl)carbamate
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Riociguat Impurity 9
CAT No: CL-RCG-10 CAS No: NA Mol Wt: 422.4 Mol F: C20H19FN8O2 Inv Status: Custom Synthesis
Chemical Name: Methyl (4,6-diamino-2-(1-(4-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl)carbamate
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Riociguat Impurity 11
CAT No: CL-RCG-11 CAS No: 256499-19-1 Mol Wt: 269.3 : 36.5 Mol F: C14H12FN5 : HCl Inv Status: Custom Synthesis
Chemical Name: 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride
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Riociguat Impurity 12
CAT No: CL-RCG-12 CAS No: NA Mol Wt: 269.3 : 36.5 Mol F: C14H12FN5 : HCl Inv Status: Custom Synthesis
Chemical Name: 1-(3-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride
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Riociguat Impurity 13
CAT No: CL-RCG-13 CAS No: 2512205-26-2 Mol Wt: 269.3 : 36.5 Mol F: C14H12FN5 : HCl Inv Status: Custom Synthesis
Chemical Name: 1-(4-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride
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Riociguat Impurity 15
CAT No: CL-RCG-14 CAS No: 1361569-10-9 Mol Wt: 376.4 Mol F: C18H13FN8O Inv Status: Custom Synthesis
Chemical Name: 6-Amino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-7,9-dihydro-8H-purin-8-one
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Riociguat Impurity 16
CAT No: CL-RCG-15 CAS No: NA Mol Wt: 298.3 Mol F: NA Inv Status: Custom Synthesis
Chemical Name: Ethyl 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b] pyridine-3-carboximidate
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Riociguat Impurity 18
CAT No: CL-RCG-16 CAS No: 1361569-18-7 Mol Wt: 390.4 Mol F: C19H15FN8O Inv Status: Custom Synthesis
Chemical Name: ethyl-Dihydropurinone {6-amino-2-[1-(2-fluorobenzyl)-1H-pyrazolo [3, 4-b] pyridin-3-yl]-7-methyl-7, 9-dihydro-8H-purin-8-one}
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Riociguat Impurity 19
CAT No: CL-RCG-17 CAS No: NA Mol Wt: NA Mol F: C20H17FN8O Inv Status: Custom Synthesis
Chemical Name: 6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7,9-dimethyl-7,9-dihydro-8H-purin-8-one
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Riociguat Intermediate
CAT No: CL-RCG-18 CAS No: 428854-23-3 Mol Wt: 439.5 Mol F: C23H18FN9 Inv Status: Custom Synthesis
Chemical Name: (E)-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(phenyldiazenyl)pyrimidine-4,6-diamine
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Riociguat Tri Amino Impurity
CAT No: CL-RCG-19 CAS No: NA Mol Wt: 350.4 Mol F: C17H15FN8 Inv Status: Custom Synthesis
Chemical Name: 2-(1-(2-Fluorobenzyl)-1H-imidazo[4,5-b]pyridin-2-yl)pyrimidine-4,5,6-triamine
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Riociguat EP Impurity A
CAT No: CL-RCG-20 CAS No: 625115-52-8 Mol Wt: 408.4 Mol F: C19H17FN8O2 Inv Status: Custom Synthesis
Chemical Name: Methyl [4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate (as per EP) ; Methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate (as per USP)
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Riociguat EP Impurity C
CAT No: CL-RCG-22 CAS No: 2920299-23-4 Mol Wt: 436.5 Mol F: C21H21FN8O2 Inv Status: Custom Synthesis
Chemical Name: Methyl [4-amino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-6-(methylamino)pyrimidin-5-yl](methyl)carbamate (as per EP) ; Methyl (4-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-(methylamino)pyrimidin-5-yl)(methyl)carbamate (as per USP)
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Riociguat EP Impurity D
CAT No: CL-RCG-23 CAS No: 625115-54-0 Mol Wt: 450.5 Mol F: C22H23FN8O2 Inv Status: Custom Synthesis
Chemical Name: Propan-2-yl [4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl](methyl)carbamate (as per EP)
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Riociguat Impurity 21
CAT No: CL-RCG-32 CAS No: 56290-86-9 Mol Wt: 141.1 Mol F: C6H7NO3 Inv Status: Custom Synthesis
Chemical Name: Ethyl 3-cyano-2-oxopropanoate
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Riociguat Impurity 22
CAT No: CL-RCG-33 CAS No: 51859-98-4 Mol Wt: 140.2 Mol F: C7H9FN2 Inv Status: Custom Synthesis
Chemical Name: (2-Fluorobenzyl)hydrazine
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Riociguat Impurity 23
CAT No: CL-RCG-34 CAS No: 4090-37-3 Mol Wt: 188.2 Mol F: C9H8N4O Inv Status: Custom Synthesis
Chemical Name: (E)-2-Cyano-2-(phenyldiazenyl)acetamide
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Riociguat Impurity 24
CAT No: CL-RCG-35 CAS No: 93866-45-6 Mol Wt: 274.3 Mol F: C15H10N6 Inv Status: Custom Synthesis
Chemical Name: 2-((E)-(4-((E)-Phenyldiazenyl)phenyl)diazenyl)malononitrile
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Riociguat Impurity 25
CAT No: CL-RCG-36 CAS No: 956011-26-0 Mol Wt: 271.3 Mol F: C14H10FN3O2 Inv Status: Custom Synthesis
Chemical Name: 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid
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Riociguat Impurity 26
CAT No: CL-RCG-37 CAS No: 256376-65-5 Mol Wt: 252.3 Mol F: C14H9FN4 Inv Status: Custom Synthesis
Chemical Name: 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
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Riociguat Impurity 27
CAT No: CL-RCG-38 CAS No: 256376-59-7 Mol Wt: 299.3 Mol F: C16H14FN3O2 Inv Status: Custom Synthesis
Chemical Name: Ethyl 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylate
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Riociguat Impurity 28
CAT No: CL-RCG-39 CAS No: NA Mol Wt: 521.5 Mol F: C28H21F2N9 Inv Status: Custom Synthesis
Chemical Name: 1-(2-fluorobenzyl)-N-((1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)(imino)methyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide
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Riociguat Impurity 29
CAT No: CL-RCG-40 CAS No: NA Mol Wt: 521.5 Mol F: C28H21F2N9 Inv Status: Custom Synthesis
Chemical Name: (E)-N-(amino(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)methylene)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide
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Riociguat Impurity 30
CAT No: CL-RCG-41 CAS No: NA Mol Wt: 405.4 Mol F: C20H20FN9 Inv Status: Custom Synthesis
Chemical Name: N'-(4,6-Diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)-N,N-dimethylformimidamide
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Riociguat Impurity 31
CAT No: CL-RCG-42 CAS No: NA Mol Wt: 408.4 Mol F: C19H17FN8O2 Inv Status: Custom Synthesis
Chemical Name: Methyl (4,6-diamino-2-(1-benzyl-5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate
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Riociguat Impurity 33
CAT No: CL-RCG-43 CAS No: NA Mol Wt: 269.3 Mol F: C14H12FN5 Inv Status: Custom Synthesis
Chemical Name: 3-(Diaziridin-3-yl)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine
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Riociguat Impurity 34
CAT No: CL-RCG-44 CAS No: 1361570-27-5 Mol Wt: 436.5 Mol F: C21H21FN8O2 Inv Status: Custom Synthesis
Chemical Name: Methyl (4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(ethyl)carbamate
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Riociguat Impurity 35
CAT No: CL-RCG-45 CAS No: 2298383-26-1 Mol Wt: 598.5 Mol F: C26H27FN8O8 Inv Status: Custom Synthesis
Chemical Name: (2S,3S,4S,5R,6R)-6-((6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-((methoxycarbonyl)(methyl)amino)pyrimidin-4-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
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Riociguat Impurity 36
CAT No: CL-RCG-46 CAS No: NA Mol Wt: 186.2 Mol F: C9H6N4O Inv Status: Custom Synthesis
Chemical Name: 1-(Dicyanomethyl)-2-phenyldiazene 1-oxide
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Riociguat Impurity 37
CAT No: CL-RCG-47 CAS No: 256376-62-2 Mol Wt: 270.3 Mol F: C14H11FN4O Inv Status: Custom Synthesis
Chemical Name: 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide
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Riociguat Impurity 38
CAT No: CL-RCG-48 CAS No: NA Mol Wt: 520.5 Mol F: C24H21FN8O5 Inv Status: Custom Synthesis
Chemical Name: (E)-4-((6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-((methoxycarbonyl)(methyl)amino)pyrimidin-4-yl)amino)-4-oxobut-2-enoic acid
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Riociguat M1 Glucuronide
CAT No: CL-RCG-49 CAS No: 2298383-28-3 Mol Wt: 584.5 Mol F: C25H25FN8O8 Inv Status: Custom Synthesis
Chemical Name: (2S,3S,4S,5R,6R)-6-((6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-((methoxycarbonyl)amino)pyrimidin-4-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
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Riociguat Metabolite M3
CAT No: CL-RCG-50 CAS No: 2298383-24-9 Mol Wt: 314.3 Mol F: C13H14N8O2 Inv Status: Custom Synthesis
Chemical Name: Methyl (4,6-diamino-2-(1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl)carbamate
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Riociguat Impurity 39
CAT No: CL-RCG-51 CAS No: NA Mol Wt: 438.4 Mol F: C20H19FN8O3 Inv Status: Custom Synthesis
Chemical Name: Methyl (4,6-diamino-2-(1-((2-fluorophenyl)(hydroxy)methyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl)carbamate
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Riociguat Impurity 40
CAT No: CL-RCG-52 CAS No: NA Mol Wt: 505.5 Mol F: C24H20FN7O5 Inv Status: Custom Synthesis
Chemical Name: (Z)-4-((1-(4-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)-2-methoxy-2-oxoethyl)amino)-4-oxobut-2-enoic acid
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Riociguat Impurity 42
CAT No: CL-RCG-53 CAS No: NA Mol Wt: 281.3 : 36.5 Mol F: C15H15N5O : HCl Inv Status: Custom Synthesis
Chemical Name: 1-(2-Methoxybenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride
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Riociguat Lactose Adduct
CAT No: CL-RCG-54 CAS No: NA Mol Wt: 746.7 Mol F: C32H39FN8O12 Inv Status: Custom Synthesis
Chemical Name: Methyl (4-amino-6-(((2S,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl)carbamate
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N-Desmethyl Riociguat-D4
CAT No: CL-RCG-55 CAS No: NA Mol Wt: 412.4 Mol F: C19H13FN8O2D4 Inv Status: Custom Synthesis
Chemical Name: Methyl (4,6-diamino-2-(1-(fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate
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Riociguat D6
CAT No: CL-RCG-56 CAS No: 1304478-43-0 Mol Wt: 428.5 Mol F: C20H13D6FN8O2 Inv Status: Custom Synthesis
Chemical Name: Methyl-d3 (4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl-d3)carbamate
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Riociguat-13C-d3
CAT No: CL-RCG-57 CAS No: 2749393-44-8 Mol Wt: 426.4 Mol F: C1913CH16FN8O2D3 Inv Status: Custom Synthesis
Chemical Name: Methyl (4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl-d3)carbamate
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Riociguat-13CD6
CAT No: CL-RCG-58 CAS No: NA Mol Wt: 429.5 Mol F: C1913CH13D6FN8O2 Inv Status: Custom Synthesis
Chemical Name: Methyl-d3 (4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl-13C-d3)carbamate
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Riociguat N-Oxide
CAT No: CL-RCG-59 CAS No: NA Mol Wt: 438.42 Mol F: C20H19FN8O3 Inv Status: In Stock
Chemical Name: 3-(4,6-diamino-5- ((methoxycarbonyl)(methyl)amino)pyrimidin- 2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo[3 ,4-b]pyridine 7-oxide

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