Impurity Reference Standard - Products

Siponimod

CAT No: CL-SPMD-01 CAS No: 1230487-00-9 Mol Wt: 516.6 Mol F: C29H35F3N2O3 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid

Siponimod Alcohol Impurity

CAT No: CL-SPMD-02 CAS No: 1418144-66-7 Mol Wt: 433.5 Mol F: C25H30F3NO2 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(3-Ethyl-4-(hydroxymethyl)phenyl)ethan-1-one O-(4-cyclohexyl-3-(trifluoromethyl)benzyl) oxime

Siponimod Aldehyde Impurity

CAT No: CL-SPMD-03 CAS No: 1230487-01-0 Mol Wt: 431.5 Mol F: C25H28F3NO2 Inv Status: Custom Synthesis

Chemical Name: (E)-4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzaldehyde

Siponimod Fumaric Acid Impurity

CAT No: CL-SPMD-04 CAS No: 110-17-8 Mol Wt: 116.1 Mol F: C4H4O4 Inv Status: Custom Synthesis

Chemical Name: Fumaric acid

Siponimod Impurity 1

CAT No: CL-SPMD-05 CAS No: NA Mol Wt: 402.5 Mol F: C22H26O5S Inv Status: Custom Synthesis

Chemical Name: 5-Acetyl-2-ethylbenzyl (4-acetyl-2-ethylphenyl)methanesulfonate

Siponimod Impurity 2

CAT No: CL-SPMD-06 CAS No: NA Mol Wt: 386.5 Mol F: C22H26O4S Inv Status: Custom Synthesis

Chemical Name: 1-(4-(((5-acetyl-2-ethylbenzyl)sulfonyl)methyl)-3-ethylphenyl)ethan-1-one

Siponimod Impurity 3

CAT No: CL-SPMD-07 CAS No: NA Mol Wt: 358.4 Mol F: C20H26N2O4 Inv Status: Custom Synthesis

Chemical Name: Methyl 1-(1-(4-acetyl-2-ethylbenzyl)azetidine-3-carbonyl)azetidine-3-carboxylate

Siponimod Impurity 4

CAT No: CL-SPMD-08 CAS No: NA Mol Wt: 390.4 Mol F: C20H26N2O6 Inv Status: Custom Synthesis

Chemical Name: Methyl (E)-1-((4-acetyl-2-ethylphenyl)((2-hydroxy-3-methoxy-3-oxopropyl)imino)methyl)azetidine-3-carboxylate

Siponimod Impurity 5

CAT No: CL-SPMD-09 CAS No: NA Mol Wt: 532.7 Mol F: C32H40N2O5 Inv Status: Custom Synthesis

Chemical Name: Methyl (Z)-1-(4-(1-(4-acetyl-2-ethylphenyl)-1-(3-(methoxycarbonyl)azetidin-1-yl)prop-1-en-2-yl)-2-ethylbenzyl)azetidine-3-carboxylate

Siponimod Impurity 6

CAT No: CL-SPMD-10 CAS No: NA Mol Wt: 613.7 Mol F: C34H42F3N3O4 Inv Status: Custom Synthesis

Chemical Name: Methyl (Z)-1-(1-(4-(1-(((4-cyclohexyl-2-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carbonyl)azetidine-3-carboxylate

Siponimod Impurity 7

CAT No: CL-SPMD-11 CAS No: NA Mol Wt: 530.6 Mol F: C30H37F3N2O3 Inv Status: Custom Synthesis

Chemical Name: Methyl (E)-1-(4-(1-(((4-cyclohexyl-2-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylate

Siponimod Impurity 8

CAT No: CL-SPMD-12 CAS No: NA Mol Wt: 256.3 Mol F: C14H15F3O Inv Status: Custom Synthesis

Chemical Name: 4-Cyclohexyl-2-(trifluoromethyl)benzaldehyde

Siponimod Impurity 10

CAT No: CL-SPMD-13 CAS No: NA Mol Wt: 532.6 Mol F: C29H35F3N2O4 Inv Status: Custom Synthesis

Chemical Name: (Z)-1-((4-(1-(((4-Cyclohexyl-2-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylphenyl)(hydroxy)methyl)azetidine-3-carboxylic acid

Siponimod Impurity 11

CAT No: CL-SPMD-14 CAS No: NA Mol Wt: 532.6 Mol F: C29H35F3N2O4 Inv Status: Custom Synthesis

Chemical Name: (Z)-1-(4-(1-(((4-Cyclohexyl-2-(trifluoromethyl)phenyl)(hydroxy)methoxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid

Siponimod Impurity 12

CAT No: CL-SPMD-15 CAS No: NA Mol Wt: 599.7 Mol F: C33H40F3N3O4 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(1-(4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carbonyl)azetidine-3-carboxylic acid

Siponimod Impurity 13

CAT No: CL-SPMD-16 CAS No: NA Mol Wt: 771.9 Mol F: C43H51F6N3O3 Inv Status: Custom Synthesis

Chemical Name: (E)-N-((4-Cyclohexyl-2-(trifluoromethyl)benzyl)oxy)-1-(4-(1-(((4-cyclohexyl-2-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxamide

Siponimod Impurity 14

CAT No: CL-SPMD-17 CAS No: NA Mol Wt: 487.6 Mol F: C29H36F3NO2 Inv Status: Custom Synthesis

Chemical Name: 1-(4-(1-(4-Cyclohexyl-2-(trifluoromethyl)phenyl)propan-2-yl)-2-ethylbenzyl)azetidine-3-carboxylic acid

Siponimod Impurity 15

CAT No: CL-SPMD-18 CAS No: NA Mol Wt: 841 Mol F: C46H54F6N4O4 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(1-(4-(1-(((4-Cyclohexyl-2-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carbonyl)-N-(4-cyclohexyl-2-(trifluoromethyl)phenoxy)azetidine-3-carboxamide

Siponimod Impurity 16

CAT No: CL-SPMD-19 CAS No: NA Mol Wt: 532.6 Mol F: C29H35F3N2O4 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(4-(1-(((4-cyclohexyl-2-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)-1-oxidoazetidine-3-carboxylate, sodium salt (1:1)

Siponimod Impurity 17

CAT No: CL-SPMD-20 CAS No: 1824308-84-0 Mol Wt: 119.1 Mol F: C4H9NO3 Inv Status: Custom Synthesis

Chemical Name: 3-Amino-2-(hydroxymethyl)propanoic acid

Siponimod Impurity 18

CAT No: CL-SPMD-21 CAS No: 1484079-83-5 Mol Wt: 133.1 Mol F: C5H11NO3 Inv Status: Custom Synthesis

Chemical Name: Methyl 3-amino-2-(hydroxymethyl)propanoate

Siponimod Impurity 19

CAT No: CL-SPMD-22 CAS No: 2247350-72-5 Mol Wt: 403.4 Mol F: C22H20F3NO3 Inv Status: Custom Synthesis

Chemical Name: 2-((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)isoindoline-1,3-dione

Siponimod Impurity 20

CAT No: CL-SPMD-23 CAS No: NA Mol Wt: 1033.2 Mol F: C58H70F6N4O6 Inv Status: Custom Synthesis

Chemical Name: 1-Cyclohexyl-2-(trifluoromethyl)benzene.

Siponimod Impurity 21

CAT No: CL-SPMD-24 CAS No: NA Mol Wt: 534.6 Mol F: C29H37F3N2O4 Inv Status: Custom Synthesis

Chemical Name: (E)-3-((4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)amino)-2-(hydroxymethyl)propanoic acid

Siponimod-Fumaric Acid impurity

CAT No: CL-SPMD-25 CAS No: NA Mol Wt: 632.7 Mol F: C33H39F3N2O7 Inv Status: Custom Synthesis

Chemical Name: (E)-4-(2-carboxy-3-((4-((E)-1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)amino)propoxy)-4-oxobut-2-enoic acid

Siponimod Impurity 22

CAT No: CL-SPMD-26 CAS No: 36476-86-5 Mol Wt: 248.3 Mol F: C17H16N2 Inv Status: Custom Synthesis

Chemical Name: 1-Benzhydrylazetidine-3-carbonitrile

Siponimod N-Oxide

CAT No: CL-SPMD-27 CAS No: NA Mol Wt: 532.6 Mol F: C29H35F3N2O4 Inv Status: Custom Synthesis

Chemical Name: (E)-3-Carboxy-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine 1-oxide

Siponimod Impurity 23

CAT No: CL-SPMD-28 CAS No: 36476-87-6 Mol Wt: 267.3 Mol F: C17H17NO2 Inv Status: Custom Synthesis

Chemical Name: 1-Benzhydrylazetidine-3-carboxylic acid

Siponimod Impurity 24

CAT No: CL-SPMD-29 CAS No: 1449293-48-4 Mol Wt: 242.3 Mol F: C14H17F3 Inv Status: Custom Synthesis

Chemical Name: 1-Cyclohexyl-4-methyl-2-(trifluoromethyl)benzene

Siponimod Impurity 25

CAT No: CL-SPMD-30 CAS No: 402-23-3 Mol Wt: 239 Mol F: C8H6BrF3 Inv Status: Custom Synthesis

Chemical Name: 1-(Bromomethyl)-3-(trifluoromethyl)benzene

Siponimod Impurity 26

CAT No: CL-SPMD-31 CAS No: 1449293-47-3 Mol Wt: 319.2 Mol F: C14H14BrF3 Inv Status: Custom Synthesis

Chemical Name: 4'-(Bromomethyl)-2'-(trifluoromethyl)-2,3,4,5-tetrahydro-1,1'-biphenyl

Siponimod Z Isomer

CAT No: CL-SPMD-32 CAS No: 2768181-14-0 Mol Wt: 516.6 Mol F: C29H35F3N2O3 Inv Status: Custom Synthesis

Chemical Name: (Z)-1-(4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid

Siponimod Impurity 27

CAT No: CL-SPMD-33 CAS No: 800380-45-4 Mol Wt: 462.6 Mol F: C29H38N2O3 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(4-(1-(((4-Cyclohexyl-3-methylbenzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid

Siponimod Impurity 28

CAT No: CL-SPMD-34 CAS No: 2746387-14-2 Mol Wt: 273.3 : 90.0 Mol F: C14H18F3NO : C2H2O4 Inv Status: Custom Synthesis

Chemical Name: O-(4-Cyclohexyl-3-(trifluoromethyl)benzyl)hydroxylamine oxalate

Siponimod Impurity 29

CAT No: CL-SPMD-35 CAS No: 40180-80-1 Mol Wt: 213.1 Mol F: C9H9BrO Inv Status: Custom Synthesis

Chemical Name: 1-(3-Bromo-4-methylphenyl)ethan-1-one

Siponimod Impurity 30

CAT No: CL-SPMD-36 CAS No: 1378888-43-7 Mol Wt: 178.2 Mol F: C11H14O2 Inv Status: Custom Synthesis

Chemical Name: 1-(3-Ethyl-4-(hydroxymethyl)phenyl)ethan-1-one

Siponimod Impurity 31

CAT No: CL-SPMD-37 CAS No: 1418144-65-6 Mol Wt: 343.4 Mol F: C18H24F3NO2 Inv Status: Custom Synthesis

Chemical Name: Ethyl (E)-N-((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)acetimidate

Siponimod Impurity 32

CAT No: CL-SPMD-38 CAS No: 1418144-63-4 Mol Wt: 176.2 Mol F: C11H12O2 Inv Status: Custom Synthesis

Chemical Name: 1-(4-(Hydroxymethyl)-3-vinylphenyl)ethan-1-one

Siponimod Impurity 33

CAT No: CL-SPMD-39 CAS No: 1418144-62-3 Mol Wt: 229.1 Mol F: C9H9BrO2 Inv Status: Custom Synthesis

Chemical Name: 1-(3-Bromo-4-(hydroxymethyl)phenyl)ethan-1-one

Siponimod Fumarate

CAT No: CL-SPMD-40 CAS No: 1234627-85-0 Mol Wt: 516.6 : 1/2(116.1) Mol F: C29H35F3N2O3 : 1/2(C4H4O4) Inv Status: Custom Synthesis

Chemical Name: (E)-1-(4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid compound with hemi fumaric acid

Siponimod Impurity 34

CAT No: CL-SPMD-41 CAS No: NA Mol Wt: 516.6 Mol F: C29H35F3N2O3 Inv Status: Custom Synthesis

Chemical Name: (E)-2-(((4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)amino)methyl)acrylic acid

Siponimod Impurity 35

CAT No: CL-SPMD-42 CAS No: NA Mol Wt: 1033.2 Mol F: C58H70F6N4O6 Inv Status: Custom Synthesis

Chemical Name: 3-((4-((E)-1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)amino)-2-(((1-(4-((E)-1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carbonyl)oxy)methyl)propanoic acid

Siponimod Impurity 36

CAT No: CL-SPMD-43 CAS No: NA Mol Wt: 410.1 Mol F: C17H14Br2O2 Inv Status: Custom Synthesis

Chemical Name: 1,1'-(Methylenebis(3-bromo-4,1-phenylene))bis(ethan-1-one)

Siponimod Impurity 37

CAT No: CL-SPMD-44 CAS No: NA Mol Wt: 596.7 Mol F: C38H39F3N2O Inv Status: Custom Synthesis

Chemical Name: (E)-1-(4-((E)-(benzhydrylimino)methyl)-3-ethylphenyl)ethan-1-one O-(4-cyclohexyl-3-(trifluoromethyl)benzyl) oxime

Siponimod Impurity 38

CAT No: CL-SPMD-45 CAS No: NA Mol Wt: 547.3 Mol F: C23H24Br2F3NO Inv Status: Custom Synthesis

Chemical Name: (E)-1-(3-Bromo-4-(bromomethyl)phenyl)ethan-1-one O-(4-cyclohexyl-3-(trifluoromethyl)benzyl) oxime

Siponimod Impurity 39

CAT No: CL-SPMD-46 CAS No: 112212-82-5 Mol Wt: 456.4 Mol F: C24H12N2O8 Inv Status: Custom Synthesis

Chemical Name: Bis(1,3-dioxoisoindolin-2-yl) phthalate

Siponimod Impurity 40

CAT No: CL-SPMD-47 CAS No: 57212-70-1 Mol Wt: 241.2 Mol F: C9H7NO5S Inv Status: Custom Synthesis

Chemical Name: 1,3-Dioxoisoindolin-2-yl methanesulfonate

Siponimod Impurity 41

CAT No: CL-SPMD-48 CAS No: NA Mol Wt: 771.9 Mol F: C43H51F6N3O3 Inv Status: Custom Synthesis

Chemical Name: (E)-N-((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxamide

Siponimod Impurity 42

CAT No: CL-SPMD-49 CAS No: NA Mol Wt: 516.6 Mol F: C29H35F3N2O3 Inv Status: Custom Synthesis

Chemical Name: (Z)-2-(((4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)amino)methyl)acrylic acid

Siponimod Impurity 43

CAT No: CL-SPMD-50 CAS No: NA Mol Wt: 534.6 Mol F: C29H37F3N2O4 Inv Status: Custom Synthesis

Chemical Name: (Z)-3-((4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)amino)-2-(hydroxymethyl)propanoic acid

Siponimod Impurity 45

CAT No: CL-SPMD-51 CAS No: 2474774-17-7 Mol Wt: 261.3 Mol F: C15H19NO3 Inv Status: Custom Synthesis

Chemical Name: 1-(4-Acetyl-2-ethylbenzyl)azetidine-3-carboxylic acid

Siponimod Impurity 46

CAT No: CL-SPMD-52 CAS No: NA Mol Wt: 512.5 Mol F: C28H30F6O2 Inv Status: Custom Synthesis

Chemical Name: 4-Cyclohexyl-3-(trifluoromethyl)benzyl 4-cyclohexyl-3-(trifluoromethyl)benzoate

Siponimod Impurity 47

CAT No: CL-SPMD-53 CAS No: NA Mol Wt: 379.3 Mol F: C19H16F3NO4 Inv Status: Custom Synthesis

Chemical Name: (E)-4-(((1-(3-ethyl-4-formylphenyl)ethylidene)amino)oxy)-3-(trifluoromethyl)benzoic acid

Siponimod Impurity 48

CAT No: CL-SPMD-54 CAS No: NA Mol Wt: 349.4 Mol F: C19H18F3NO2 Inv Status: Custom Synthesis

Chemical Name: (E)-2-Ethyl-4-(1-(((3-(trifluoromethyl)benzyl)oxy)imino)ethyl)benzaldehyde

Siponimod Impurity 49

CAT No: CL-SPMD-55 CAS No: NA Mol Wt: 501.7 Mol F: C28H34F3NO2Si Inv Status: Custom Synthesis

Chemical Name: (E)-1-(4-(Hydroxymethyl)-3-((trimethylsilyl)ethynyl)phenyl)ethan-1-one O-(4-cyclohexyl-3-(trifluoromethyl)benzyl) oxime

Siponimod Impurity 50

CAT No: CL-SPMD-56 CAS No: NA Mol Wt: 484.4 Mol F: C23H25BrF3NO2 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(3-Bromo-4-(hydroxymethyl)phenyl)ethan-1-one O-(4-cyclohexyl-3-(trifluoromethyl)benzyl) oxime

Siponimod Impurity 51

CAT No: CL-SPMD-57 CAS No: 19532-96-8 Mol Wt: 276.4 Mol F: C16H24N2O2 Inv Status: Custom Synthesis

Chemical Name: N1,N2-Dibutylphthalamide

Siponimod Impurity 52

CAT No: CL-SPMD-58 CAS No: 36476-80-9 Mol Wt: 393.5 Mol F: C23H23NO3S Inv Status: Custom Synthesis

Chemical Name: 1-Benzhydrylazetidin-3-yl 4-methylbenzenesulfonate

Siponimod Impurity 53

CAT No: CL-SPMD-59 CAS No: NA Mol Wt: 417.5 Mol F: C25H30F3NO Inv Status: Custom Synthesis

Chemical Name: (E)-1-(3-ethyl-4-methylphenyl)ethan-1-one O-(4-cyclohexyl-3-(trifluoromethyl)benzyl) oxime

Siponimod Impurity 54

CAT No: CL-SPMD-60 CAS No: NA Mol Wt: 279.3 Mol F: C15H21NO4 Inv Status: Custom Synthesis

Chemical Name: 3-((4-Acetyl-2-ethylbenzyl)amino)-2-(hydroxymethyl)propanoic acid

Siponimod d11

CAT No: CL-SPMD-61 CAS No: NA Mol Wt: 527.7 Mol F: C29H24D11F3N2O3 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(4-(1-(((4-(Cyclohexyl-d11)-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid

Siponimod-D5

CAT No: CL-SPMD-62 CAS No: 2104759-51-3 Mol Wt: 521.6 Mol F: C29H30D5F3N2O3 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)phenyl)methoxy-d2)imino)ethyl-2,2,2-d3)-2-ethylbenzyl)azetidine-3-carboxylic acid

Des Cyclohexyl Siponimod Impurity

CAT No: CL-SPMD-63 CAS No: NA Mol Wt: 434.5 : 116.1 Mol F: C23H25F3N2O3 : C4H4O4 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(2-ethyl-4-(1-(((3-(trifluoromethyl)benzyl)oxy)imino)ethyl)benzyl)azetidine-3-carboxylic acid

Siponimod Azetidine Acid Impurity

CAT No: CL-SPMD-64 CAS No: NA Mol Wt: 585.7 Mol F: C33H42F3N3O3 Inv Status: Custom Synthesis

Chemical Name: ?(E)-1-((1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidin-3-yl)methyl)azetidine-3-carboxylic acid

Siponimod Desethyl Impurity

CAT No: CL-SPMD-65 CAS No: 2768181-18-4 Mol Wt: 488.6 Mol F: C27H31F3N2O3 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)benzyl)azetidine-3-carboxylic acid

Siponimod Dimer Impurity

CAT No: CL-SPMD-66 CAS No: NA Mol Wt: 1033.2 Mol F: C58H70F6N4O6 Inv Status: Custom Synthesis

Chemical Name: Siponimod Dimer Impurity

Siponimod

CAT No: CL-SPMD-67 CAS No: 2305339-41-5 Mol Wt: 516.6 : 116.1 Mol F: C29H35F3N2O3 : C4H4O4 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid compound with fumaric acid

Siponimod Impurity 55

CAT No: CL-SPMD-68 CAS No: 1589558-70-2 Mol Wt: 299.2 Mol F: C14H19BrO2 Inv Status: Custom Synthesis

Chemical Name: 2-((4-Bromo-2-ethylbenzyl)oxy)tetrahydro-2H-pyran

Siponimod Impurity 56

CAT No: CL-SPMD-69 CAS No: 916806-97-8 Mol Wt: 272.3 Mol F: C14H15F3O2 Inv Status: Custom Synthesis

Chemical Name: 4-Cyclohexyl-3-(trifluoromethyl)benzoic acid

Siponimod Impurity 57

CAT No: CL-SPMD-70 CAS No: 13376-27-7 Mol Wt: 228.3 Mol F: C13H15F3 Inv Status: Custom Synthesis

Chemical Name: 1-Cyclohexyl-2-(trifluoromethyl)benzene

Siponimod Impurity 58

CAT No: CL-SPMD-71 CAS No: 1449291-53-5 Mol Wt: 307.2 Mol F: C13H14BrF3 Inv Status: Custom Synthesis

Chemical Name: 4-Bromo-1-cyclohexyl-2-(trifluoromethyl)benzene

Siponimod Impurity 59

CAT No: CL-SPMD-72 CAS No: 2768181-12-8 Mol Wt: 514.6 Mol F: C29H33F3N2O3 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(2-ethyl-4-(1-(((2-(trifluoromethyl)-2',3',4',5'-tetrahydro-[1,1'-biphenyl]-4-yl)methoxy)imino)ethyl)benzyl)azetidine-3-carboxylic acid

Siponimod Impurity 60

CAT No: CL-SPMD-73 CAS No: 2768181-13-9 Mol Wt: 514.6 Mol F: C29H33F3N2O3 Inv Status: Custom Synthesis

Chemical Name: (E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-vinylbenzyl)azetidine-3-carboxylic acid

Siponimod Impurity 62

CAT No: CL-SPMD-74 CAS No: NA Mol Wt: 447.5 Mol F: C25H28F3NO3 Inv Status: Custom Synthesis

Chemical Name: (E)-4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzoic acid

Siponimod Methyl Ester Impurity

CAT No: CL-SPMD-75 CAS No: 2746387-08-4 Mol Wt: 530.6 Mol F: C30H37F3N2O3 Inv Status: Custom Synthesis

Chemical Name: Methyl (E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylate

Siponimod Hemifumarate

CAT No: CL-SPMD-76 CAS No: 1234627-85-0 Mol Wt: 516.6 : 1/2(116.1) Mol F: C29H35F3N2O3 : 1/2(C4H4O4) Inv Status: Custom Synthesis

Chemical Name: (E)-1-(4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid compound with hemi fumaric acid

Type:Impurity Reference Standard

API NAME:Siponimod

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