Impurity Reference Standard - Products

Ticagrelor

CAT No: CL-TGR-01 CAS No: 274693-27-5 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity A

CAT No: CL-TGR-02 CAS No: 1251765-07-7 Mol Wt: 370.43 Mol F: C14H22N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-[7-Amino-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity B

CAT No: CL-TGR-03 CAS No: 2216753-87-4 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1R,2R,3S,5R)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor EP Impurity C

CAT No: CL-TGR-04 CAS No: 1616703-93-5 Mol Wt: 564.6 Mol F: C25H30F2N6O5S Inv Status: Custom Synthesis

Chemical Name: 2-[[(1S,2S,3S,4R)-4-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-2,3-dihydroxycyclopentyl]oxy]ethyl acetate

Ticagrelor Impurity G (Ticagrelor Metabolite)

CAT No: CL-TGR-05 CAS No: 220347-05-7 Mol Wt: 478.52 Mol F: C21H24F2N6O3S Inv Status: Custom Synthesis

Chemical Name: (1S,2R,3S,4R)-4-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-1,2,3-cyclopentanetriol

Ticagrelor EP Impurity B

CAT No: CL-TGR-06 CAS No: 1788033-05-5 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-((3-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor EP Impurity E Hydrochloride

CAT No: CL-TGR-07 CAS No: 1402222-66-5 Mol Wt: 169.2 : 36.5 Mol F: C9H9F2N : HCl Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine Hydrochloride

Ticagrelor EP Impurity D Hydrochloride

CAT No: CL-TGR-08 CAS No: 1883662-29-0 Mol Wt: 562.6 Mol F: C26H32F2N6O4S Inv Status: Custom Synthesis

Chemical Name: 2-[[(3aR,4S,6R,6aS)-6-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-2,2-dimethyltetrahydro-2H,3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethan-1-ol

Ticagrelor EP Impurity A

CAT No: CL-TGR-09 CAS No: 1251765-07-7 Mol Wt: 370.4 Mol F: C14H22N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-[7-amino-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor EP Impurity D

CAT No: CL-TGR-10 CAS No: 274693-26-4 Mol Wt: 562.6 Mol F: C26H32F2N6O4S Inv Status: Custom Synthesis

Chemical Name: 2-[[(3aR,4S,6R,6aS)-6-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-2,2-dimethyltetrahydro-2H,3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethan-1-ol

Ticagrelor EP Impurity D Hydrobromide

CAT No: CL-TGR-11 CAS No: 1883662-31-4 Mol Wt: 562.6 Mol F: C26H32F2N6O4S Inv Status: Custom Synthesis

Chemical Name: 2-[[(3aR,4S,6R,6aS)-6-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-2,2-dimethyltetrahydro-2H,3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethan-1-ol

Ticagrelor EP Impurity E (Succinate salt)

CAT No: CL-TGR-12 CAS No: 220352-39-6 Mol Wt: 169.2 Mol F: C9H9F2N Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine

Ticagrelor Impurity 1

CAT No: CL-TGR-13 CAS No: 2206827-26-9 Mol Wt: 573.6 Mol F: C27H27NO9S2 Inv Status: Custom Synthesis

Chemical Name: benzyl (1S,4R,5S,6R)-5,6-bis(tosyloxy)-2-oxa-3-azabicyclo[2.2.1]heptane-3-carboxylate

Ticagrelor Impurity 2

CAT No: CL-TGR-14 CAS No: 2204863-18-1 Mol Wt: 419.5 Mol F: C20H21NO7S Inv Status: Custom Synthesis

Chemical Name: benzyl (1S,4R,5S,6S)-5-hydroxy-6-(tosyloxy)-2-oxa-3-azabicyclo[2.2.1]heptane-3-carboxylate

Ticagrelor Impurity 3

CAT No: CL-TGR-15 CAS No: 2206827-21-4 Mol Wt: 419.5 Mol F: C20H21NO7S Inv Status: Custom Synthesis

Chemical Name: benzyl (1S,4R,5S,6R)-6-hydroxy-5-(tosyloxy)-2-oxa-3-azabicyclo[2.2.1]heptane-3-carboxylate

Ticagrelor Enantiomer impurity

CAT No: CL-TGR-16 CAS No: 2096989-55-6 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: [(1R,2R,3S,5R)-3-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol]

Ticagrelor Impurity 4

CAT No: CL-TGR-17 CAS No: 2248538-63-6 Mol Wt: 389.9 Mol F: C14H20ClN5O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 5

CAT No: CL-TGR-18 CAS No: 2165881-71-8 Mol Wt: 217.26 Mol F: C10H19NO4 Inv Status: Custom Synthesis

Chemical Name: 2-(((3aS,4R,6S,6aR)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol

Ticagrelor Impurity 6

CAT No: CL-TGR-19 CAS No: 1643378-48-6 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(2,3-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 7

CAT No: CL-TGR-20 CAS No: NA Mol Wt: 217.27 : 150.1 Mol F: C10H19NO4 : C4H6O6 Inv Status: Custom Synthesis

Chemical Name: (R)-1-(((3aS,4R,6S,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol (2R)-2,3-dihydroxysuccinate

Ticagrelor Impurity 8

CAT No: CL-TGR-21 CAS No: 1402150-10-0 Mol Wt: 564.6 Mol F: C25H30F2N6O5S Inv Status: Custom Synthesis

Chemical Name: ethyl 2-(((1S,2S,3S,4R)-4-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,3-dihydroxycyclopentyl)oxy)acetate

Ticagrelor Impurity 9

CAT No: CL-TGR-22 CAS No: 1402149-98-7 Mol Wt: 259.3 : 90.0 Mol F: 259.3 : 90.0 Inv Status: Custom Synthesis

Chemical Name: Ethyl 2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate oxalate

Ticagrelor Impurity 10

CAT No: CL-TGR-23 CAS No: 19009-67-7 Mol Wt: 147.2 Mol F: C10H13N Inv Status: Custom Synthesis

Chemical Name: 2-(p-tolyl)cyclopropan-1-amine

Ticagrelor Impurity 11

CAT No: CL-TGR-24 CAS No: NA Mol Wt: 204.7 Mol F: C7H9ClN2OS Inv Status: Custom Synthesis

Chemical Name: 6-chloro-2-(propylthio)pyrimidin-4-ol

Ticagrelor Impurity 12

CAT No: CL-TGR-25 CAS No: 1863036-51-4 Mol Wt: 594.6 Mol F: C26H32F2N6O6S Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylsulfonyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 13

CAT No: CL-TGR-26 CAS No: 1863036-49-0 Mol Wt: 578.6 Mol F: C26H32F2N6O5S Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylsulfinyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 14

CAT No: CL-TGR-27 CAS No: 1808068-84-9 Mol Wt: 185.6 Mol F: C9H9ClFN Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(4-chloro-3-fluorophenyl)cyclopropanamine

Ticagrelor Impurity 15

CAT No: CL-TGR-28 CAS No: NA Mol Wt: 539 Mol F: C23H28ClFN6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3-chloro-4-fluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol

Ticagrelor Desfluoro analogue

CAT No: CL-TGR-29 CAS No: NA Mol Wt: 504.6 Mol F: C23H29FN6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3-Fluorophenyl) cyclopropylamino]-5-(propyl thio)-3H-[1,2,3]triazolo [4,5-d] pyrimidin-3-yl]-5-(2-hydroxyethoxy) cyclopentane-1,2-diol

Ticagrelor Desethoxy impurity

CAT No: CL-TGR-30 CAS No: NA Mol Wt: 478.5 Mol F: C21H24F2N6O3S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylthio)- 3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl] cyclopentane-1,2,5-triol

Ticagrelor Impurity 62

CAT No: CL-TGR-31 CAS No: NA Mol Wt: 551.6 : 36.5 Mol F: C23H27F2N7O5S : HCl Inv Status: Custom Synthesis

Chemical Name: N-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-N-(3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)nitrous amide hydrochloride

Ticagrelor Impurity 63

CAT No: CL-TGR-32 CAS No: NA Mol Wt: 169.2 : 152.1 Mol F: C9H9F2N : C8H8O3 Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(3,5-difluorophenyl)cyclopropan-1-amine 2-hydroxy-2-phenylacetate

Ticagrelor Impurity 64

CAT No: CL-TGR-33 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: [1S-[1a,2a,3b(1S*,2R*)5b] ]-3-[7-(2-(3,4-difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxy ethoxy)-cyclopentane-1,2 diol

Ticagrelor Impurity 65

CAT No: CL-TGR-34 CAS No: 145783-13-7 Mol Wt: 231.2 Mol F: C7H9N3O4S Inv Status: Custom Synthesis

Chemical Name: 6-hydroxy-5-nitro-2-(propylthio)pyrimidin-4(3H)-one

Ticagrelor Impurity 66

CAT No: CL-TGR-35 CAS No: 145783-12-6 Mol Wt: 186.2 Mol F: C7H10N2O2S Inv Status: Custom Synthesis

Chemical Name: S-Propyl-2-thiobarbituric Acid

Ticagrelor Impurity 67

CAT No: CL-TGR-36 CAS No: 274693-53-7 Mol Wt: 307.3 Mol F: C16H21NO5 Inv Status: Custom Synthesis

Chemical Name: Phenylmethyl ester N-[(3aS,4R,6S,6aR)-tetrahydro-6-hydroxy-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]-Carbamic acid

Ticagrelor Impurity 68

CAT No: CL-TGR-37 CAS No: 274693-54-8 Mol Wt: 351.4 Mol F: C18H25NO6 Inv Status: Custom Synthesis

Chemical Name: Benzyl ((3aS,4R,6S,6aR)-6-(2-Hydroxyethoxy)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)carbamate

Ticagrelor Impurity 70

CAT No: CL-TGR-38 CAS No: 1820580-27-5 Mol Wt: 185.6 Mol F: C9H9ClFN Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(4-chloro-3-fluorophenyl)cyclopropan-1-amine

Ticagrelor Impurity 71

CAT No: CL-TGR-39 CAS No: 3721-26-4 Mol Wt: 133.2 Mol F: C9H11N Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-phenylcyclopropan-1-amine

Ticagrelor Impurity 72

CAT No: CL-TGR-40 CAS No: 220241-60-1 Mol Wt: 374.9 Mol F: C15H23ClN4O3S Inv Status: Custom Synthesis

Chemical Name: (3aR,4S,6R,6aS)-6-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Impurity 73

CAT No: CL-TGR-41 CAS No: NA Mol Wt: 418.9 Mol F: C17H27ClN4O4S Inv Status: Custom Synthesis

Chemical Name: 2-(((3aS,4R,6S,6aR)-6-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 74

CAT No: CL-TGR-42 CAS No: 220241-61-2 Mol Wt: 385.9 Mol F: C15H20ClN5O3S Inv Status: Custom Synthesis

Chemical Name: (3aR,4S,6R,6aS)-6-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Impurity 75

CAT No: CL-TGR-43 CAS No: 1402150-01-9 Mol Wt: 472 Mol F: C19H26ClN5O5S Inv Status: Custom Synthesis

Chemical Name: Ethyl 2-(((3aR,4S,6R,6aS)-6-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate

Ticagrelor Impurity 76

CAT No: CL-TGR-44 CAS No: 274693-49-1 Mol Wt: 518.6 Mol F: C24H28F2N6O3S Inv Status: Custom Synthesis

Chemical Name: (3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Impurity 77

CAT No: CL-TGR-45 CAS No: 2245167-79-5 Mol Wt: 478.5 Mol F: C21H24F2N6O3S Inv Status: Custom Synthesis

Chemical Name: (1S,2R,3S,4R)-4-(7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2,3-triol

Ticagrelor Impurity 78

CAT No: CL-TGR-46 CAS No: 2248538-63-6 Mol Wt: 389.9 Mol F: C14H20ClN5O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 79

CAT No: CL-TGR-47 CAS No: NA Mol Wt: 447.9 Mol F: C17H26ClN5O5S Inv Status: Custom Synthesis

Chemical Name: N-(5-Amino-6-chloro-2-(propylthio)pyrimidin-4-yl)-N-((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)nitrous amide

Ticagrelor Impurity 80

CAT No: CL-TGR-48 CAS No: NA Mol Wt: 186.2 Mol F: C7H10N2O2S Inv Status: Custom Synthesis

Chemical Name: 4,6-Dihydroxy-2-(propylsulfanyl)pyrimidine

Ticagrelor Impurity 81

CAT No: CL-TGR-49 CAS No: NA Mol Wt: 185.6 : 36.5 Mol F: C9H9ClFN : HCl Inv Status: Custom Synthesis

Chemical Name: 2-(3-Chloro-4-fluorophenyl)cyclopropan-1-amine hydrochloride

Ticagrelor Impurity 82

CAT No: CL-TGR-50 CAS No: 1304995-11-6 Mol Wt: 185.6 : 36.5 Mol F: C9H9ClFN : HCl Inv Status: Custom Synthesis

Chemical Name: 2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine hydrochloride

Ticagrelor Impurity 83

CAT No: CL-TGR-51 CAS No: 1414348-35-8 Mol Wt: 169.2 Mol F: C9H9F2N Inv Status: Custom Synthesis

Chemical Name: (1R,2R)-2-(3,4-difluorophenyl)cyclopropan-1-amine

Ticagrelor Acetyl Impurity

CAT No: CL-TGR-52 CAS No: NA Mol Wt: 562.6 Mol F: C26H32F2N6O4S Inv Status: Custom Synthesis

Chemical Name: 2-((3aR,4S,6S,6aS)-6-(7-((1R,2S)-2-(3,4-difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta [d][1,3]dioxol-4-yloxy)ethanol

Ticagrelor Impurity 85

CAT No: CL-TGR-53 CAS No: NA Mol Wt: 407.9 Mol F: C14H22ClN5O5S Inv Status: Custom Synthesis

Chemical Name: N-(5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)-N-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)nitrous amide

Ticagrelor Impurity 86

CAT No: CL-TGR-54 CAS No: NA Mol Wt: 447.9 Mol F: C17H26ClN5O5S Inv Status: Custom Synthesis

Chemical Name: N-(5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)-N-((4R,6S)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)nitrous amide

Ticagrelor Impurity 87

CAT No: CL-TGR-55 CAS No: 1350749-64-2 Mol Wt: 269.3 Mol F: C14H17F2NO2 Inv Status: Custom Synthesis

Chemical Name: Tert-butyl ((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)carbamate

Ticagrelor Impurity 88

CAT No: CL-TGR-56 CAS No: NA Mol Wt: 446.9 Mol F: C18H27ClN4O5S Inv Status: Custom Synthesis

Chemical Name: N-(3-amino-4-chloro-6-(propylthio)pyridin-2-yl)-N-((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)nitrous amide

Ticagrelor Impurity 89

CAT No: CL-TGR-57 CAS No: NA Mol Wt: 169.2 : 36.5 Mol F: C9H9F2N : HCl Inv Status: Custom Synthesis

Chemical Name: (1S,2R)-2-(2,3- difluorophenyl) cyclopropanamine hydrochloride

Ticagrelor Impurity 90

CAT No: CL-TGR-58 CAS No: NA Mol Wt: 303.3 Mol F: C17H18FNO3 Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(3-fluorophenyl)cyclopropanamine-hydroxy(phenyl)ethanoate

Ticagrelor Impurity 91

CAT No: CL-TGR-59 CAS No: NA Mol Wt: 217.3 Mol F: C10H19NO4 Inv Status: Custom Synthesis

Chemical Name: 2-(((3aS,4R,6R,6aR)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol

Ticagrelor Impurity 92

CAT No: CL-TGR-60 CAS No: NA Mol Wt: 217.3 Mol F: C10H19NO4 Inv Status: Custom Synthesis

Chemical Name: 2-(((3aS,4S,6S,6aR)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol

Ticagrelor Impurity 93

CAT No: CL-TGR-61 CAS No: 2376278-69-0 Mol Wt: 217.3 Mol F: C10H19NO4 Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6S,6aS)-6-Amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 94

CAT No: CL-TGR-62 CAS No: 1822472-41-2 Mol Wt: 307.3 Mol F: C16H21NO5 Inv Status: Custom Synthesis

Chemical Name: Benzyl (6-hydroxy-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)carbamate

Ticagrelor Impurity 95

CAT No: CL-TGR-63 CAS No: 88756-84-7 Mol Wt: 307.3 Mol F: C16H21NO5 Inv Status: Custom Synthesis

Chemical Name: Benzyl ((3aR,4S,6R,6aS)-6-hydroxy-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)carbamate

Ticagrelor Impurity 96

CAT No: CL-TGR-64 CAS No: 4137-56-8 Mol Wt: 358.4 Mol F: C16H22O7S Inv Status: Custom Synthesis

Chemical Name: Methyl 2,3-O-Isopropylidene-5-O-tosyl-?-D-ribofuranoside

Ticagrelor Impurity 97

CAT No: CL-TGR-65 CAS No: NA Mol Wt: 204.2 Mol F: C9H16O5 Inv Status: Custom Synthesis

Chemical Name: (3aR,4R,6S,6aS)-4,6-dimethoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Ticagrelor Impurity 98

CAT No: CL-TGR-66 CAS No: NA Mol Wt: 305.4 Mol F: C16H17O4S Inv Status: Custom Synthesis

Chemical Name: 2-(benzyloxy)ethyl-4-methylbenzenesulfonate

Ticagrelor Impurity 99

CAT No: CL-TGR-67 CAS No: 106-94-5 Mol Wt: 123 Mol F: C3H7Br Inv Status: Custom Synthesis

Chemical Name: 1-Bromopropane

Ticagrelor Impurity 100

CAT No: CL-TGR-68 CAS No: 39856-08-1 Mol Wt: 226.7 Mol F: C11H11ClO3 Inv Status: Custom Synthesis

Chemical Name: (E)-3-(3,4-dimethoxyphenyl)acryloyl chloride

Ticagrelor Impurity 101

CAT No: CL-TGR-69 CAS No: NA Mol Wt: NA Mol F: NA Inv Status: Custom Synthesis

Chemical Name: Ticagrelor Impurity 101

Ticagrelor Impurity 102

CAT No: CL-TGR-70 CAS No: 1006376-62-0 Mol Wt: 197.2 Mol F: C10H9F2NO Inv Status: Custom Synthesis

Chemical Name: (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxamide

Ticagrelor Impurity 103

CAT No: CL-TGR-71 CAS No: NA Mol Wt: 217.3 : 150.1 Mol F: C10H19NO4 : C4H6O6 Inv Status: Custom Synthesis

Chemical Name: 2-(((3aS,4R,6S,6aR)-6-Amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol (2R,3R)-2,3-dihydroxysuccinate

Ticagrelor Impurity 104

CAT No: CL-TGR-72 CAS No: 1858267-99-8 Mol Wt: 410.5 Mol F: C17H26N6O4S Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-(7-amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 105

CAT No: CL-TGR-73 CAS No: 1644461-85-7 Mol Wt: 538.6 Mol F: C23H28F2N6O5S Inv Status: Custom Synthesis

Chemical Name: (1s,2s,3r,5s)-3-[7-[(1r,2s)-2-(3,4-difluorophenyl)cyclopropylamino]-5-(propylsulfinyl)-3h-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 106

CAT No: CL-TGR-74 CAS No: 1345413-20-8 Mol Wt: 169.2 Mol F: C9H9F2N Inv Status: Custom Synthesis

Chemical Name: (1S,2R)-2-(3,4-Difluorophenyl)cyclopropan-1-amine

Ticagrelor Impurity 107

CAT No: CL-TGR-75 CAS No: 2880337-24-4 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3S,5R)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 108

CAT No: CL-TGR-76 CAS No: NA Mol Wt: 184.1 Mol F: C9H6F2O2 Inv Status: Custom Synthesis

Chemical Name: (Z)-3-(3,4-Difluorophenyl)acrylic acid

Ticagrelor Impurity 109

CAT No: CL-TGR-77 CAS No: 152152-17-5 Mol Wt: 184.1 Mol F: C9H6F2O2 Inv Status: Custom Synthesis

Chemical Name: (E)-3-(3,4-Difluorophenyl)acrylic acid

Ticagrelor Impurity 110

CAT No: CL-TGR-78 CAS No: 1043546-64-0 Mol Wt: 202.6 Mol F: C9H5ClF2O Inv Status: Custom Synthesis

Chemical Name: 3-(3,4-Difluorophenyl)acryloyl chloride

Ticagrelor Impurity 111

CAT No: CL-TGR-79 CAS No: 220352-29-4 Mol Wt: 381.4 Mol F: C19H21F2NO3S Inv Status: Custom Synthesis

Chemical Name: (E)-3-(3,4-Difluorophenyl)-1-((6R,7aR)-8,8-dimethyl-2,2-dioxidotetrahydro-3H-3a,6-methanobenzo[c]isothiazol-1(4H)-yl)prop-2-en-1-one

Ticagrelor Impurity 112

CAT No: CL-TGR-80 CAS No: 220352-32-9 Mol Wt: 395.5 Mol F: C20H23F2NO3S Inv Status: Custom Synthesis

Chemical Name: ((1R,2R)-2-(3,4-Difluorophenyl)cyclopropyl)((6R,7aR)-8,8-dimethyl-2,2-dioxidotetrahydro-3H-3a,6-methanobenzo[c]isothiazol-1(4H)-yl)methanone

Ticagrelor Impurity 113

CAT No: CL-TGR-81 CAS No: 108448-77-7 Mol Wt: 215.3 Mol F: C10H17NO2S Inv Status: Custom Synthesis

Chemical Name: (6S,7aS)-8,8-Dimethylhexahydro-3H-3a,6-methanobenzo[c]isothiazole 2,2-dioxide

Ticagrelor Impurity 114

CAT No: CL-TGR-82 CAS No: 376608-70-7 Mol Wt: 216.6 Mol F: C10H7ClF2O Inv Status: Custom Synthesis

Chemical Name: (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl chloride

Ticagrelor Impurity 115

CAT No: CL-TGR-83 CAS No: 1258651-83-0 Mol Wt: 151.2 : 36.5 Mol F: C9H10FN : HCl Inv Status: Custom Synthesis

Chemical Name: 2-(3-Fluorophenyl)cyclopropan-1-amine hydrochloride

Ticagrelor Impurity 116

CAT No: CL-TGR-84 CAS No: 1156491-10-9 Mol Wt: 169.2 : 36.5 Mol F: C9H9F2N : HCl Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(3,4-Difluorophenyl)cyclopropan-1-amine hydrochloride

Ticagrelor Impurity 117

CAT No: CL-TGR-85 CAS No: 1427324-45-5 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: 3-(7-((2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 118

CAT No: CL-TGR-86 CAS No: 504-17-6 Mol Wt: 144.1 Mol F: C4H4N2O2S Inv Status: Custom Synthesis

Chemical Name: 2-Mercaptopyrimidine-4,6-diol

Ticagrelor Impurity 119

CAT No: CL-TGR-87 CAS No: 1549834-66-3 Mol Wt: 201.3 Mol F: C7H11N3O2S Inv Status: Custom Synthesis

Chemical Name: 5-amino-2-(propylthio)pyrimidine-4,6-diol

Ticagrelor Impurity 120

CAT No: CL-TGR-88 CAS No: NA Mol Wt: 762.9 Mol F: C34H50N8O8S2 Inv Status: Custom Synthesis

Chemical Name: 2,2'-(((3aS,3a'S,4R,4'R,6S,6aR,6'S,6a'R)-((2,7-bis(propylthio)pyrimido[4,5-g]pteridine-4,9-diyl)bis(azanediyl))bis(2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxole-6,4-diyl))bis(oxy))bis(ethan-1-ol)

Ticagrelor Impurity 121

CAT No: CL-TGR-89 CAS No: NA Mol Wt: 682.8 Mol F: C28H42N8O8S2 Inv Status: Custom Synthesis

Chemical Name: (1R,1'R,2R,2'R,3R,3'R,5S,5'S)-5,5'-((2,7-bis(propylthio)pyrimido[4,5-g]pteridine-4,9-diyl)bis(azanediyl))bis(3-(2-hydroxyethoxy)cyclopentane-1,2-diol)

Ticagrelor Impurity 122

CAT No: CL-TGR-90 CAS No: 1353964-89-2 Mol Wt: 223.2 Mol F: C11H7F2NO2 Inv Status: Custom Synthesis

Chemical Name: (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carbonyl isocyanate

Ticagrelor Impurity 123

CAT No: CL-TGR-91 CAS No: NA Mol Wt: 398.4 Mol F: C15H22N6O5S Inv Status: Custom Synthesis

Chemical Name: N-(3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)formamide

Ticagrelor Impurity 124

CAT No: CL-TGR-92 CAS No: NA Mol Wt: 185.2 Mol F: C7H11N3OS Inv Status: Custom Synthesis

Chemical Name: 5-Amino-2-(propylthio)pyrimidin-4-ol

Ticagrelor Impurity 125

CAT No: CL-TGR-93 CAS No: NA Mol Wt: 345.4 Mol F: C16H27NO7 Inv Status: Custom Synthesis

Chemical Name: Ethyl ((3aS,4R,6S,6aR)-6-(2-ethoxy-2-oxoethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)glycinate

Ticagrelor Impurity 126

CAT No: CL-TGR-94 CAS No: NA Mol Wt: 259.3 Mol F: C12H21NO5 Inv Status: Custom Synthesis

Chemical Name: Ethyl 2-amino-2-((3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)acetate

Ticagrelor Impurity 127

CAT No: CL-TGR-95 CAS No: 2230124-25-9 Mol Wt: 245.3 : 90.0 Mol F: C11H19NO5 : C2H2O4 Inv Status: Custom Synthesis

Chemical Name: Methyl 2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate oxalate

Ticagrelor IP impurity C

CAT No: CL-TGR-96 CAS No: 2417326-48-6 Mol Wt: 538.6 Mol F: C23H28F2N6O5S Inv Status: In Stock

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-((S)-propylsulfinyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity M

CAT No: CL-TGR-97 CAS No: 274693-39-9 Mol Wt: 554.57 Mol F: C23H28F2N6O6S Inv Status: In Stock

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylsulfonyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TCG-38 Diol

CAT No: CL-TGR-98 CAS No: 1354945-69-9 Mol Wt: 389.86 Mol F: C14H20ClN5O4S Inv Status: In Stock

Chemical Name: 2-[[(3aR,4S,6R,6aS)-6-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol

Ticagrelor Acetonide

CAT No: CL-TGR-99 CAS No: 274693-26-4 Mol Wt: 562.63 Mol F: C26H32F2N6O4S Inv Status: In Stock

Chemical Name: 2-[[(3aR,4S,6R,6aS)-6-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol

Deshydroxyethoxy Ticagrelor

CAT No: CL-TGR-100 CAS No: 220347-05-7 Mol Wt: 478.52 Mol F: C21H24F2N6O3S Inv Status: In Stock

Chemical Name: (1S,2R,3S,4R)-4-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-1,2,3-cyclopentanetriol

Ticagrelor Related Compound 57

CAT No: CL-TGR-101 CAS No: 1402150-32-6 Mol Wt: 378.87 Mol F: C14H23ClN4O4S Inv Status: In Stock

Chemical Name: (1S,2S,3S,5S)-3-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 134

CAT No: CL-TGR-102 CAS No: 220352-36-3 Mol Wt: 198.2 Mol F: C10H8F2O2 Inv Status: Custom Synthesis

Chemical Name: (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carboxylic acid

Ticagrelor Related Compound A

CAT No: CL-TGR-103 CAS No: 376608-71-8 Mol Wt: 321.32 Mol F: C9H9F2N.C8H8O3 Inv Status: In Stock

Chemical Name: ((1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine (R)-mandelate)

Ticagrelor Impurity 136

CAT No: CL-TGR-104 CAS No: 1350563-61-9 Mol Wt: 218.7 Mol F: C7H11ClN4S Inv Status: Custom Synthesis

Chemical Name: 6-Chloro-2-(propylthio)pyrimidine-4,5-diamine

Ticagrelor Impurity 137

CAT No: CL-TGR-105 CAS No: NA Mol Wt: 620.6 Mol F: C24H35Cl2N7O4S2 Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-((5-((5-Amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor (1R,2R,3R,5S) Isomer

CAT No: CL-TGR-106 CAS No: 2435586-25-5 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1R,2R,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 138

CAT No: CL-TGR-107 CAS No: NA Mol Wt: 394.9 Mol F: C14H23ClN4O5S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-((5-amino-6-chloro-2-(propylsulfinyl)pyrimidin-4-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 139

CAT No: CL-TGR-108 CAS No: 2024557-22-8 Mol Wt: 385.4 Mol F: C15H23N5O5S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3S,5R)-3-(2-Hydroxyethoxy)-5-(7-methoxy-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2-diol

Ticagrelor Impurity 140

CAT No: CL-TGR-109 CAS No: NA Mol Wt: 537.5 Mol F: C22H25F2N7O5S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((E)-2-(3,4-difluorophenyl)-2-nitrosovinyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 141

CAT No: CL-TGR-110 CAS No: 2724654-42-4 Mol Wt: 217.3 Mol F: C10H19NO4 Inv Status: Custom Synthesis

Chemical Name: 2-(((3aS,4S,6S,6aR)-6-Amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

4,5-Dihydroisoxazole Derivative of Ticagrelor

CAT No: CL-TGR-111 CAS No: NA Mol Wt: 551.6 Mol F: C23H27F2N7O5S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-((3-(3,4-difluorophenyl)-4,5-dihydroisoxazol-5-yl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor EP Impurity E

CAT No: CL-TGR-112 CAS No: 220352-38-5 Mol Wt: 169.2 Mol F: C9H9F2N Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine

Ticagrelor Impurity 142

CAT No: CL-TGR-113 CAS No: NA Mol Wt: 401.3 Mol F: C14H14Cl2N6S2 Inv Status: Custom Synthesis

Chemical Name: 4,9-Dichloro-2,7-bis(propylthio)pyrimido[4,5-g]pteridine

Ticagrelor Impurity 143

CAT No: CL-TGR-114 CAS No: 1459720-31-0 Mol Wt: 198.2 Mol F: C10H8F2O2 Inv Status: Custom Synthesis

Chemical Name: (1S,2S)-2-(3,4-Difluorophenyl)cyclopropane-1-carboxylic acid

Ticagrelor Impurity 144

CAT No: CL-TGR-115 CAS No: 2376278-80-5 Mol Wt: 173.2 Mol F: C8H15NO3 Inv Status: Custom Synthesis

Chemical Name: (3aR,4S,6S,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Impurity 145

CAT No: CL-TGR-116 CAS No: NA Mol Wt: 173.2 Mol F: C8H15NO3 Inv Status: Custom Synthesis

Chemical Name: (3aS,4S,6R,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Impurity 146

CAT No: CL-TGR-117 CAS No: NA Mol Wt: 173.2 Mol F: C8H15NO3 Inv Status: Custom Synthesis

Chemical Name: (3aS,4R,6R,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Impurity 147

CAT No: CL-TGR-118 CAS No: 2715109-35-4 Mol Wt: 173.2 Mol F: C8H15NO3 Inv Status: Custom Synthesis

Chemical Name: (3aR,4R,6S,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Impurity 148

CAT No: CL-TGR-119 CAS No: NA Mol Wt: 173.2 Mol F: C8H15NO3 Inv Status: Custom Synthesis

Chemical Name: (3aS,4S,6S,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Impurity 149

CAT No: CL-TGR-120 CAS No: 2165675-01-2 Mol Wt: 195.2 Mol F: C11H14FNO Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(3-Ethoxy-4-fluorophenyl)cyclopropan-1-amine

Ticagrelor Impurity 150

CAT No: CL-TGR-121 CAS No: 1402150-26-8 Mol Wt: 365.4 Mol F: C18H23NO7 Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-(((benzyloxy)carbonyl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetic acid

Ticagrelor Impurity 151

CAT No: CL-TGR-122 CAS No: NA Mol Wt: 432.5 : 150.1 Mol F: C20H36N2O8 : C4H6O6 Inv Status: Custom Synthesis

Chemical Name: 2,4-Bis(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)butane-1,3-diol (2R,3R)-2,3-dihydroxysuccinate

Ticagrelor Impurity 152

CAT No: CL-TGR-123 CAS No: 2051515-36-5 Mol Wt: 198.2 Mol F: C10H8F2O2 Inv Status: Custom Synthesis

Chemical Name: (1S,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carboxylic acid

Ticagrelor Impurity 153

CAT No: CL-TGR-124 CAS No: 1414348-38-1 Mol Wt: 198.2 Mol F: C10H8F2O2 Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(3,4-Difluorophenyl)cyclopropane-1-carboxylic acid

Ticagrelor Impurity 154

CAT No: CL-TGR-125 CAS No: 345898-95-5 Mol Wt: 261.3 Mol F: C15H19NO3 Inv Status: Custom Synthesis

Chemical Name: (Z)-N-Benzyl-1-((4S,5R)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)methanimine oxide

Ticagrelor Impurity 155

CAT No: CL-TGR-126 CAS No: 879396-75-5 Mol Wt: 151.2 Mol F: C9H10FN Inv Status: Custom Synthesis

Chemical Name: 2-(4-Fluorophenyl)cyclopropan-1-amine

Ticagrelor Impurity 156

CAT No: CL-TGR-127 CAS No: 38838-06-1 Mol Wt: 314.1 Mol F: C9H15IO4 Inv Status: Custom Synthesis

Chemical Name: (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Ticagrelor Impurity 157

CAT No: CL-TGR-128 CAS No: 16633-44-6 Mol Wt: 176.2 Mol F: C11H12O2 Inv Status: Custom Synthesis

Chemical Name: (1R,2R)-2-(p-tolyl)cyclopropane-1-carboxylic acid

Ticagrelor Impurity 158

CAT No: CL-TGR-129 CAS No: NA Mol Wt: 267.3 Mol F: C13H17NO5 Inv Status: Custom Synthesis

Chemical Name: Benzyl ((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)carbamate

Ticagrelor Impurity 159

CAT No: CL-TGR-130 CAS No: 2051515-32-1 Mol Wt: 226.2 Mol F: C12H12F2O2 Inv Status: Custom Synthesis

Chemical Name: Ethyl (1S,2S)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate

(1R,2R)-2-(4-fluorophenyl)cyclopropanamine HCl

CAT No: CL-TGR-131 CAS No: 1450903-24-8 Mol Wt: 151.2 : 36.5 Mol F: C9H10FN : HCl Inv Status: Custom Synthesis

Chemical Name: (1R,2R)-2-(4-fluorophenyl)cyclopropanamine hydrochloride

(S)-2-(3,4-Difluorophenyl)oxirane

CAT No: CL-TGR-132 CAS No: 1006376-63-1 Mol Wt: 156.1 Mol F: C8H6F2O Inv Status: Custom Synthesis

Chemical Name: (S)-2-(3,4-difluorophenyl)oxirane

2-Chloro-1-(3,4-difluorophenyl)ethanol

CAT No: CL-TGR-133 CAS No: 51336-97-1 Mol Wt: 192.6 Mol F: C8H7ClF2O Inv Status: Custom Synthesis

Chemical Name: ?2-Chloro-1-(3,4-difluorophenyl)ethan-1-ol

4-Fluoro Ticagrelor

CAT No: CL-TGR-134 CAS No: 1643378-47-5 Mol Wt: 504.6 Mol F: C23H29FN6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(4-fluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor (2R)-Epimer

CAT No: CL-TGR-135 CAS No: 2056269-94-2 Mol Wt: 522.6 Mol F: C23H28F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 130

CAT No: CL-TGR-136 CAS No: 1006376-61-9 Mol Wt: 226.2 Mol F: C12H12F2O2 Inv Status: Custom Synthesis

Chemical Name: Ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate

Ticagrelor Impurity 175

CAT No: CL-TGR-137 CAS No: NA Mol Wt: 151.2 : 152.1 Mol F: C9H10FN : C8H8O3 Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(4-fluorophenyl)cyclopropan-1-amine (S)-2-hydroxy-2-phenylacetate

Ticagrelor Impurity Q

CAT No: CL-TGR-138 CAS No: 2205903-74-6 Mol Wt: 610.7 Mol F: C27H42N6O8S Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-((3-((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Intermediate

CAT No: CL-TGR-139 CAS No: 145783-14-8 Mol Wt: 268.1 Mol F: C7H7Cl2N3O2S Inv Status: Custom Synthesis

Chemical Name: 4,6-dichloro-5-nitro-2-(propylthio)pyrimidine

Ticagrelor Intermediate 4

CAT No: CL-TGR-140 CAS No: 34328-61-5 Mol Wt: 158.6 Mol F: C7H4ClFO Inv Status: Custom Synthesis

Chemical Name: 3-chloro-4-fluorobenzaldehyde

Ticagrelor IP Impurity D

CAT No: CL-TGR-141 CAS No: 2417798-14-0 Mol Wt: 538.6 Mol F: C23H28F2N6O5S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-((R)-propylsulfinyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 1

CAT No: CL-TGR-142 CAS No: 155899-66-4 Mol Wt: 173.2 Mol F: C8H15NO3 Inv Status: Custom Synthesis

Chemical Name: (3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Related Compound 12

CAT No: CL-TGR-143 CAS No: 1630025-26-1 Mol Wt: 562.6 Mol F: C26H32F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-((3-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 16

CAT No: CL-TGR-144 CAS No: 2096989-56-7 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 17

CAT No: CL-TGR-145 CAS No: 376608-74-1 Mol Wt: 418.9 Mol F: C17H27ClN4O4S Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 19

CAT No: CL-TGR-146 CAS No: 2378409-07-3 Mol Wt: 263.8 Mol F: C9H14ClN3O2S? Inv Status: Custom Synthesis

Chemical Name: 2-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 2

CAT No: CL-TGR-147 CAS No: 592533-90-9 Mol Wt: 173.2 Mol F: C8H15NO3? Inv Status: Custom Synthesis

Chemical Name: (3aS,4R,6S,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Related Compound 29

CAT No: CL-TGR-148 CAS No: NA Mol Wt: 259.3 : 150.1 Mol F: C12H21NO5 : C4H6O6 Inv Status: Custom Synthesis

Chemical Name: Ethyl 2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate (2R,3R)-2,3-dihydroxysuccinate

Ticagrelor Related Compound 47

CAT No: CL-TGR-149 CAS No: 1445580-43-7 Mol Wt: 371.4 Mol F: C14H21N5O5S? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5R)-3-(7-hydroxy-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 49

CAT No: CL-TGR-150 CAS No: 866551-95-3 Mol Wt: 393.4 Mol F: C20H27NO7 Inv Status: Custom Synthesis

Chemical Name: Ethyl 2-(((3aR,4S,6R,6aS)-6-(((benzyloxy)carbonyl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate

Ticagrelor Related Compound 56

CAT No: CL-TGR-151 CAS No: 1628340-74-8 Mol Wt: 604.7 Mol F: C28H34F2N6O5S Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethyl acetate

Ticagrelor Related Compound 6 (S)-Mandelic Acid

CAT No: CL-TGR-152 CAS No: NA Mol Wt: NA Mol F: C9H9F2N : C8H8O3 Inv Status: Custom Synthesis

Chemical Name: (1S,2R)-2-(3,4-difluorophenyl)cyclopropan-1-amine (S)-2-hydroxy-2-phenylacetate

Ticagrelor Related Compound 62

CAT No: CL-TGR-153 CAS No: 1823431-32-8 Mol Wt: 254.1 Mol F: C7H9Cl2N3OS Inv Status: Custom Synthesis

Chemical Name: 4,6-Dichloro-2-(propylsulfinyl)pyrimidin-5-amine

Ticagrelor Related Compound 63 HCl

CAT No: CL-TGR-154 CAS No: 1314324-00-9 Mol Wt: 151.2 : 36.5 Mol F: C9H10FN : HCl? Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(4-fluorophenyl)cyclopropan-1-amine hydrochloride

Ticagrelor Related Compound 65

CAT No: CL-TGR-155 CAS No: 2205903-72-4 Mol Wt: 530.6 Mol F: C21H34N6O8S? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-((3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 69

CAT No: CL-TGR-156 CAS No: 145783-13-7 Mol Wt: 231.2 Mol F: C7H9N3O4S Inv Status: Custom Synthesis

Chemical Name: 5-nitro-2-(propylthio)pyrimidine-4,6-diol

Ticagrelor Related Compound 71

CAT No: CL-TGR-157 CAS No: 1548397-10-9 Mol Wt: 249.7 Mol F: C7H8ClN3O3S Inv Status: Custom Synthesis

Chemical Name: 6-Chloro-5-nitro-2-(propylthio)pyrimidin-4(1H)-one

Ticagrelor Related Compound 75

CAT No: CL-TGR-158 CAS No: 1401318-10-2 Mol Wt: 223.1 Mol F: C7H8Cl2N2S? Inv Status: Custom Synthesis

Chemical Name: 4,6-dichloro-2-(propylthio)pyrimidine

Ticagrelor Related Compound 88 HCl

CAT No: CL-TGR-159 CAS No: 1990505-73-1 Mol Wt: 151.2 : 36.5 Mol F: C9H10FN : HCl? Inv Status: Custom Synthesis

Chemical Name: (1S,2R)-2-(4-fluorophenyl)cyclopropan-1-amine hydrochloride

TKMDIP-1

CAT No: CL-TGR-160 CAS No: 2518331-26-3 Mol Wt: 233.7 Mol F: C7H8ClN3O2S? Inv Status: Custom Synthesis

Chemical Name: 4-Chloro-5-nitro-2-(propylthio)pyrimidine

TKMDIP-2

CAT No: CL-TGR-161 CAS No: 2514951-26-7 Mol Wt: 229.3 Mol F: C8H11N3O3S Inv Status: Custom Synthesis

Chemical Name: 4-methoxy-5-nitro-2-(propylthio)pyrimidine

Ticagrelor Intermediate 2

CAT No: CL-TGR-162 CAS No: 376608-65-0 Mol Wt: 217.3 : 150.1 Mol F: C10H19NO4 : C4H6O6 Inv Status: Custom Synthesis

Chemical Name: 2-((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aHcyclopenta[d][1,3]dioxol-4-yloxy)ethanol (2R,3R)-2,3-dihydroxysuccinate.

Ticagrelor Related Compound 89

CAT No: CL-TGR-163 CAS No: 2518048-22-9 Mol Wt: 203.7 Mol F: C7H10ClN3S? Inv Status: Custom Synthesis

Chemical Name: 4-chloro-2-(propylthio)pyrimidin-5-amine

Ticagrelor (1S)-Epimer

CAT No: CL-TGR-164 CAS No: 2435586-40-4 Mol Wt: 522.6 Mol F: C23H28F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: ?(1S,2S,3R,5S)-3-(7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 76

CAT No: CL-TGR-165 CAS No: 145783-15-9 Mol Wt: 238.1 Mol F: C7H9Cl2N3S? Inv Status: Custom Synthesis

Chemical Name: 4,6-dichloro-2-(propylthio)pyrimidin-5-amine

(1S,2S)-2-(4-fluorophenyl)cyclopropanamine HCl

CAT No: CL-TGR-166 CAS No: NA Mol Wt: 151.18 : 36.5 Mol F: C9H10FN : HCl? Inv Status: Custom Synthesis

Chemical Name: (1S,2S)-2-(4-fluorophenyl)cyclopropan-1-amine hydrochloride

Methoxy Ticagrelor Intermediate

CAT No: CL-TGR-167 CAS No: NA Mol Wt: 403.9 Mol F: C15H22ClN5O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-methoxyethoxy)cyclopentane-1,2-diol

O-Tert-Butyl Ticagrelor Impurity

CAT No: CL-TGR-168 CAS No: NA Mol Wt: 578.7 Mol F: C27H36F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2R,3S,5R)-3-(2-(Tert-butoxy)ethoxy)-5-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2-diol

Ticagrelor (1R,2R,3S,5S) Isomer

CAT No: CL-TGR-169 CAS No: 2435586-11-9 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1R,2R,3S,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 131

CAT No: CL-TGR-170 CAS No: NA Mol Wt: 169.2 : 36.5 Mol F: C9H9F2N : HCl Inv Status: Custom Synthesis

Chemical Name: 2-(3,5-Difluorophenyl)cyclopropan-1-amine hydrochloride

Ticagrelor Impurity 132

CAT No: CL-TGR-171 CAS No: 1402150-31-5 Mol Wt: 446.9 Mol F: C18H27ClN4O5S Inv Status: Custom Synthesis

Chemical Name: N-(4-Chloro-6-(((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)amino)-2-(propylthio)pyrimidin-5-yl)formamide

Ticagrelor Impurity 133

CAT No: CL-TGR-172 CAS No: NA Mol Wt: 580.6 Mol F: C25H30F2N6O6S Inv Status: Custom Synthesis

Chemical Name: 2-(((1S,2S,3S,4R)-4-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylsulfinyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,3-dihydroxycyclopentyl)oxy)ethyl acetate

Ticagrelor Impurity 135

CAT No: CL-TGR-173 CAS No: 633312-86-4 Mol Wt: 169.2 Mol F: C9H9F2N Inv Status: Custom Synthesis

Chemical Name: 2-(3,4-Difluorophenyl)cyclopropan-1-amine

Ticagrelor Impurity 160

CAT No: CL-TGR-174 CAS No: 2227875-43-4 Mol Wt: 181.2 Mol F: C10H12FNO Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(4-Fluoro-3-methoxyphenyl)cyclopropan-1-amine

Ticagrelor Impurity 161

CAT No: CL-TGR-175 CAS No: 220352-92-1 Mol Wt: 181.2 Mol F: C10H12FNO Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(3-Fluoro-4-methoxyphenyl)cyclopropan-1-amine

Ticagrelor Impurity 162

CAT No: CL-TGR-176 CAS No: NA Mol Wt: 398.5 Mol F: C16H26N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(ethylamino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 163

CAT No: CL-TGR-177 CAS No: NA Mol Wt: 534.6 Mol F: C24H31FN6O5S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(4-fluoro-3-methoxyphenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 164

CAT No: CL-TGR-178 CAS No: NA Mol Wt: 534.6 Mol F: C24H31FN6O5S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3-fluoro-4-methoxyphenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 165

CAT No: CL-TGR-179 CAS No: NA Mol Wt: 318.3 Mol F: C14H12F2N6O Inv Status: Custom Synthesis

Chemical Name: N-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)-5-methoxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine

Ticagrelor Impurity 166

CAT No: CL-TGR-180 CAS No: NA Mol Wt: 362.4 Mol F: C16H16F2N6S Inv Status: Custom Synthesis

Chemical Name: N-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine

Ticagrelor Impurity 167

CAT No: CL-TGR-181 CAS No: NA Mol Wt: 464.4 Mol F: C20H22F2N6O5 Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-hydroxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 168

CAT No: CL-TGR-182 CAS No: NA Mol Wt: 478.5 Mol F: C21H24F2N6O5 Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-methoxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 169

CAT No: CL-TGR-183 CAS No: NA Mol Wt: 217.3 Mol F: C10H19NO4 Inv Status: Custom Synthesis

Chemical Name: rel-2-(((3aR,4R,6S,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 170

CAT No: CL-TGR-184 CAS No: 2703957-62-2 Mol Wt: 217.3 Mol F: C10H19NO4 Inv Status: Custom Synthesis

Chemical Name: rel-2-(((3aR,4S,6S,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 171

CAT No: CL-TGR-185 CAS No: 1822784-83-7 Mol Wt: 226.2 Mol F: C12H12F2O2 Inv Status: Custom Synthesis

Chemical Name: Ethyl 2-(3,4-difluorophenyl)cyclopropane-1-carboxylate

Ticagrelor Impurity 172

CAT No: CL-TGR-186 CAS No: 1274778-02-7 Mol Wt: 169.2 Mol F: C9H9F2N Inv Status: Custom Synthesis

Chemical Name: 2-(2,3-Difluorophenyl)cyclopropan-1-amine

Ticagrelor Impurity 173

CAT No: CL-TGR-187 CAS No: NA Mol Wt: 195.2 Mol F: C9H7F2N3 Inv Status: Custom Synthesis

Chemical Name: 4-((1S,2R)-2-azidocyclopropyl)-1,2-difluorobenzene

Ticagrelor Impurity 174

CAT No: CL-TGR-188 CAS No: 2880337-23-3 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3S,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 176

CAT No: CL-TGR-189 CAS No: 51336-95-9 Mol Wt: 190.6 Mol F: C8H5ClF2O Inv Status: Custom Synthesis

Chemical Name: 2-Chloro-1-(3,4-difluorophenyl)ethan-1-one

Ticagrelor Impurity 177

CAT No: CL-TGR-190 CAS No: 1353964-60-9 Mol Wt: 213.2 Mol F: C10H9F2NO2 Inv Status: Custom Synthesis

Chemical Name: (1R,2R)-2-(3,4-Difluorophenyl)-N-hydroxycyclopropane-1-carboxamide

Ticagrelor Impurity 178

CAT No: CL-TGR-191 CAS No: 1006376-60-8 Mol Wt: 192.6 Mol F: C8H7ClF2O Inv Status: Custom Synthesis

Chemical Name: (S)-2-Chloro-1-(3,4-difluorophenyl)ethan-1-ol

Ticagrelor Impurity 179

CAT No: CL-TGR-192 CAS No: 1459720-02-5 Mol Wt: 212.2 Mol F: C11H10F2O2 Inv Status: Custom Synthesis

Chemical Name: Methyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate

Ticagrelor Impurity 180

CAT No: CL-TGR-193 CAS No: 50600-40-3 Mol Wt: 314.1 Mol F: C9H15IO4 Inv Status: Custom Synthesis

Chemical Name: (3aS,4S,6aR)-4-(iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Ticagrelor Impurity 181

CAT No: CL-TGR-194 CAS No: 155934-55-7 Mol Wt: 156.2 Mol F: C8H12O3 Inv Status: Custom Synthesis

Chemical Name: (4R,5R)-2,2-Dimethyl-5-vinyl-1,3-dioxolane-4-carbaldehyde

Ticagrelor Impurity 182

CAT No: CL-TGR-195 CAS No: 1381841-36-6 Mol Wt: 261.3 Mol F: C15H19NO3 Inv Status: Custom Synthesis

Chemical Name: (Z)-N-Benzyl-1-((4S,5R)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)methanimine oxide

Ticagrelor Impurity 183

CAT No: CL-TGR-196 CAS No: 155855-51-9 Mol Wt: 261.3 Mol F: C15H19NO3 Inv Status: Custom Synthesis

Chemical Name: (3aS,4S,7R,7aS)-6-Benzyl-2,2-dimethyltetrahydro-4H-4,7-methano[1,3]dioxolo[4,5-d][1,2]oxazine

Ticagrelor Impurity 184

CAT No: CL-TGR-197 CAS No: 376608-68-3 Mol Wt: 336.4 Mol F: C20H26F2O2 Inv Status: Custom Synthesis

Chemical Name: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate

Ticagrelor Impurity 187

CAT No: CL-TGR-198 CAS No: NA Mol Wt: 554.6 Mol F: C23H28F2N6O6S Inv Status: Custom Synthesis

Chemical Name: (R)-3-(3,4-Difluorophenyl)-N-(3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-3-hydroxypropanamide

Ticagrelor Impurity 189

CAT No: CL-TGR-199 CAS No: NA Mol Wt: 599.7 Mol F: C27H45N5O8S Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-((5-Amino-6-(((3aR,4S,6R,6aS)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)amino)-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 193

CAT No: CL-TGR-200 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: 3-(7-Amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-(2-(3,4-difluorophenyl)cyclopropoxy)ethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 194

CAT No: CL-TGR-201 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: 5-(7-Amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2-(2-(3,4-difluorophenyl)cyclopropoxy)-3-(2-hydroxyethoxy)cyclopentan-1-ol

Ticagrelor Impurity 195

CAT No: CL-TGR-202 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: 3-(7-Amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2-(2-(3,4-difluorophenyl)cyclopropoxy)-5-(2-hydroxyethoxy)cyclopentan-1-ol

Ticagrelor Impurity 197

CAT No: CL-TGR-203 CAS No: NA Mol Wt: 538.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1R,2R,3S,5R)-3-(7-(((1R,2R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity D

CAT No: CL-TGR-204 CAS No: NA Mol Wt: 538.6 Mol F: C23H28F2N6O5S Inv Status: Custom Synthesis

Chemical Name: (1R,2R,3R,5R)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylsulfinyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor IP Impurity G

CAT No: CL-TGR-205 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor N-Formyl Impurity

CAT No: CL-TGR-206 CAS No: NA Mol Wt: 550.6 Mol F: C24H28F2N6O5S Inv Status: Custom Synthesis

Chemical Name: N-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-N-(3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)formamide

Ticagrelor N-Glucuronide

CAT No: CL-TGR-207 CAS No: NA Mol Wt: 698.7 Mol F: C29H36F2N6O10S? Inv Status: Custom Synthesis

Chemical Name: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

Ticagrelor O-Glucuronide

CAT No: CL-TGR-208 CAS No: NA Mol Wt: 698.7 Mol F: C29H36F2N6O10S? Inv Status: Custom Synthesis

Chemical Name: 6-(2-(((1S,2S,3S,4R)-4-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,3-dihydroxycyclopentyl)oxy)ethoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

Ticagrelor Pyrimidine Dimer

CAT No: CL-TGR-209 CAS No: 2205903-73-5 Mol Wt: 732.3 Mol F: C28H42ClN9O8S2 Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-((6-chloro-5-((3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-2-(propylthio)pyrimidin-4-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 11

CAT No: CL-TGR-210 CAS No: NA Mol Wt: 169.2 : 36.5 Mol F: C9H9F2N : HCl Inv Status: Custom Synthesis

Chemical Name: (1S,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine hydrochloride

Ticagrelor Related Compound 18

CAT No: CL-TGR-211 CAS No: NA Mol Wt: 725.2 Mol F: C30H35ClF2N8O5S2? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3S,5R)-3-(2-((6-chloro-5-hydroxy-2-(propylthio)pyrimidin-4-yl)oxy)ethoxy)-5-(7-(((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2-diol

Ticagrelor Related Compound 20

CAT No: CL-TGR-212 CAS No: NA Mol Wt: 465.4 Mol F: C16H22Cl2N6O2S2 Inv Status: Custom Synthesis

Chemical Name: 6,6'-(ethane-1,2-diylbis(oxy))bis(4-chloro-2-(propylthio)pyrimidin-5-amine)

Ticagrelor Related Compound 22

CAT No: CL-TGR-213 CAS No: NA Mol Wt: 177.2 Mol F: C7H15NO4? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5R)-3-amino-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 23

CAT No: CL-TGR-214 CAS No: NA Mol Wt: 177.2 Mol F: C7H15NO4 Inv Status: Custom Synthesis

Chemical Name: (1R,2S,3R,5S)-3-amino-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 24

CAT No: CL-TGR-215 CAS No: NA Mol Wt: 177.2 Mol F: C7H15NO4 Inv Status: Custom Synthesis

Chemical Name: (1R,2R,3R,5S)-3-amino-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 25

CAT No: CL-TGR-216 CAS No: NA Mol Wt: 177.2 Mol F: C7H15NO4 Inv Status: Custom Synthesis

Chemical Name: (1S,2R,3R,5S)-3-amino-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 26

CAT No: CL-TGR-217 CAS No: NA Mol Wt: 177.2 Mol F: C7H15NO4? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3S,5S)-3-amino-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 3

CAT No: CL-TGR-218 CAS No: 88756-83-6 Mol Wt: 173.2 Mol F: C8H15NO3 Inv Status: Custom Synthesis

Chemical Name: (3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Related Compound 32 (DP1)

CAT No: CL-TGR-219 CAS No: NA Mol Wt: 344.4 Mol F: C14H24N4O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5R)-3-((6-amino-2-(propylthio)pyrimidin-4-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 33 (DP4)

CAT No: CL-TGR-220 CAS No: 1644461-92-6 Mol Wt: 538.6 Mol F: C23H28F2N6O5S? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(hydroxy)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 34 (DP6)

CAT No: CL-TGR-221 CAS No: NA Mol Wt: 536.6 Mol F: C23H26F2N6O5S Inv Status: Custom Synthesis

Chemical Name: 2-(3,4-difluorophenyl)-3-((3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)cyclopropan-1-one

Ticagrelor Related Compound 35 (DP7)

CAT No: CL-TGR-223 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-((1R,2S)-2-(3,4-difluorophenyl)cyclopropoxy)ethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 36 (DP8)

CAT No: CL-TGR-224 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3S,5R)-5-(7-amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2-((1R,2S)-2-(3,4-difluorophenyl)cyclopropoxy)-3-(2-hydroxyethoxy)cyclopentan-1-ol

Ticagrelor Related Compound 37 (DP9)

CAT No: CL-TGR-225 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3S,5R)-5-(7-amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2-((1S,2R)-2-(3,4-difluorophenyl)cyclopropoxy)-3-(2-hydroxyethoxy)cyclopentan-1-ol

Ticagrelor Related Compound 39

CAT No: CL-TGR-226 CAS No: NA Mol Wt: 620.7 Mol F: C25H37Cl2N6O4S2? Inv Status: Custom Synthesis

Chemical Name: N4-((3aS,4R,6R,6aR)-6-(2-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)oxy)ethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)-6-chloro-2-(propylthio)pyrimidine-4,5-diamine

Ticagrelor Related Compound 4

CAT No: CL-TGR-227 CAS No: 1446475-48-4 Mol Wt: 173.2 Mol F: C8H15NO3? Inv Status: Custom Synthesis

Chemical Name: (6-Aminotetrahydro-2,2-Dimethyl-4H-Cyclopenta-1.3-dioxol-4-ol)

Ticagrelor Related Compound 40

CAT No: CL-TGR-228 CAS No: NA Mol Wt: 599.8 Mol F: C27H45N5O8S? Inv Status: Custom Synthesis

Chemical Name: 2,2'-(((3aR,3a'R,4S,4'S,6S,6aS,6'S,6a'S)-((5-amino-2-(propylthio)pyrimidine-4,6-diyl)bis(azanediyl))bis(2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxole-6,4-diyl))bis(oxy))bis(ethan-1-ol)

Ticagrelor Related Compound 41

CAT No: CL-TGR-229 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3S,5S)-3-((3-((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 42

CAT No: CL-TGR-230 CAS No: 1424142-79-9 Mol Wt: 151.2 : 36.5 Mol F: C9H10FN : HCl Inv Status: Custom Synthesis

Chemical Name: (1S,2R)-2-(3-fluorophenyl)cyclopropan-1-amine hydrochloride

Ticagrelor Related Compound 43

CAT No: CL-TGR-231 CAS No: 1156491-05-2 Mol Wt: 167.6 : 36.5 Mol F: C9H10ClN : HCl Inv Status: Custom Synthesis

Chemical Name: (1S,2R)-2-(3-chlorophenyl)cyclopropan-1-amine hydrochloride

Ticagrelor Related Compound 44

CAT No: CL-TGR-232 CAS No: 1431867-40-1 Mol Wt: 233.7 Mol F: C8H12ClN3OS Inv Status: Custom Synthesis

Chemical Name: 4-chloro-2-methoxy-6-(propylthio)pyridin-3-amine

Ticagrelor Related Compound 46

CAT No: CL-TGR-233 CAS No: NA Mol Wt: 732.3 Mol F: C28H42ClN9O8S2 Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3S,5S)-3-((6-chloro-5-((3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-2-(propylthio)pyrimidin-4-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 5 (HCl salt)

CAT No: CL-TGR-234 CAS No: NA Mol Wt: 169.2 : 36.5 Mol F: C9H9F2N : HCl Inv Status: Custom Synthesis

Chemical Name: (1R,2R)-2-(3,4-difluorophenyl)cyclopropan-1-amine hydrochloride

Ticagrelor Related Compound 50

CAT No: CL-TGR-235 CAS No: 1548397-26-7 Mol Wt: 400.5 Mol F: C17H28N4O5S Inv Status: Custom Synthesis

Chemical Name: 5-amino-6-(((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)amino)-2-(propylthio)pyrimidin-4-ol

Ticagrelor Related Compound 51

CAT No: CL-TGR-236 CAS No: NA Mol Wt: 411.5 Mol F: C17H25N5O5S Inv Status: Custom Synthesis

Chemical Name: 3-((3aS,4R,6R,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol

Ticagrelor Related Compound 52

CAT No: CL-TGR-237 CAS No: 1265919-25-2 Mol Wt: 448.9 Mol F: C17H25ClN4O6S Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-((6-chloro-5-nitro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 53

CAT No: CL-TGR-238 CAS No: NA Mol Wt: 631.6 Mol F: C24H32Cl2N8O4S2? Inv Status: Custom Synthesis

Chemical Name: 4-chloro-6-(2-(((3aR,4S,6R,6aS)-6-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethoxy)-2-(propylthio)pyrimidin-5-amine

Ticagrelor Related Compound 54

CAT No: CL-TGR-239 CAS No: NA Mol Wt: 610.7 Mol F: C27H42N6O8S? Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6S,6aS)-6-((3-((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 55

CAT No: CL-TGR-240 CAS No: 1402150-00-8 Mol Wt: 461 Mol F: C20H31ClN3O5S Inv Status: Custom Synthesis

Chemical Name: Ethyl 2-(((3aR,4S,6R,6aS)-6-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate

Ticagrelor Related Compound 58

CAT No: CL-TGR-241 CAS No: NA Mol Wt: 812.4 Mol F: C34H50ClN9O8S2? Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6S,6aS)-6-((6-chloro-5-((3-((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 60

CAT No: CL-TGR-242 CAS No: NA Mol Wt: 410.5 Mol F: C17H26N6O4S? Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4R,6R,6aS)-6-(7-amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 61

CAT No: CL-TGR-243 CAS No: 1630025-27-2 Mol Wt: 581.7 Mol F: C26H33F2N5O6S? Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-((6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-nitro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 64

CAT No: CL-TGR-244 CAS No: 131844-33-2 Mol Wt: 151.2 Mol F: C9H10FN Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(3-fluorophenyl)cyclopropan-1-amine

Ticagrelor Related Compound 67

CAT No: CL-TGR-245 CAS No: NA Mol Wt: 536.6 Mol F: C24H30F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-methoxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 68

CAT No: CL-TGR-246 CAS No: 2165799-36-8 Mol Wt: 217.3 Mol F: C10H19NO4? Inv Status: Custom Synthesis

Chemical Name: 2-(((3aS,4S,6R,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 70

CAT No: CL-TGR-247 CAS No: 1482484-92-3 Mol Wt: 201.3 Mol F: C7H11N3O2S? Inv Status: Custom Synthesis

Chemical Name: 5-amino-2-(propylthio)pyrimidine-4,6-diol

Ticagrelor Related Compound 73

CAT No: CL-TGR-248 CAS No: 2517939-84-1 Mol Wt: 254.1 Mol F: C7H9Cl2N3OS Inv Status: Custom Synthesis

Chemical Name: N-(4,6-dichloro-2-(propylthio)pyrimidin-5-yl)hydroxylamine

Ticagrelor Related Compound 74

CAT No: CL-TGR-249 CAS No: 2512210-19-2 Mol Wt: 252.1 Mol F: C7H7Cl2N3OS? Inv Status: Custom Synthesis

Chemical Name: 4,6-dichloro-5-nitroso-2-(propylthio)pyrimidine

Ticagrelor Related Compound 77

CAT No: CL-TGR-250 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: (1R,2R,3S,5R)-3-(7-(((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 78

CAT No: CL-TGR-251 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: (1R,2R,3R,5R)-3-(7-(((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 79

CAT No: CL-TGR-252 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5R)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 8

CAT No: CL-TGR-253 CAS No: 378236-67-0 Mol Wt: 223.2 Mol F: C10H7F2N3O Inv Status: Custom Synthesis

Chemical Name: (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carbonyl azide

Ticagrelor Related Compound 80

CAT No: CL-TGR-254 CAS No: 2435586-08-4 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5R)-3-(7-(((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 81

CAT No: CL-TGR-255 CAS No: 2435586-09-5 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5R)-3-(7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 82

CAT No: CL-TGR-256 CAS No: 2435586-10-8 Mol Wt: 522.6 Mol F: C23H28F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5R)-3-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 83

CAT No: CL-TGR-257 CAS No: 2435586-12-0 Mol Wt: 522.6 Mol F: C23H28F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1R,2R,3S,5S)-3-(7-(((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 85

CAT No: CL-TGR-258 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: (1R,2R,3S,5S)-3-(7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 86

CAT No: CL-TGR-259 CAS No: NA Mol Wt: 522.6 Mol F: C23H28F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: (1R,2R,3S,5S)-3-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 87

CAT No: CL-TGR-260 CAS No: 274693-55-9 Mol Wt: 217.3 Mol F: C10H19NO4 Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 90

CAT No: CL-TGR-261 CAS No: NA Mol Wt: 185.6 : 152.1 Mol F: C9H9ClFN : C8H8O3 Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(3-chloro-4-fluorophenyl)cyclopropanamine Mandelate

Ticagrelor Related Compound 91

CAT No: CL-TGR-262 CAS No: 2376278-68-9 Mol Wt: 217.3 : 150.1 Mol F: C10H19NO4 : C4H6O6 Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4R,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol (2R,3R)-2,3-dihydroxysuccinate

Ticagrelor Related Compound 92

CAT No: CL-TGR-263 CAS No: NA Mol Wt: 418.9 Mol F: C17H27ClN4O4S? Inv Status: Custom Synthesis

Chemical Name: 2-(((3aS,4S,6R,6aR)-6-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 93

CAT No: CL-TGR-264 CAS No: NA Mol Wt: 419 Mol F: C17H27ClN4O4S? Inv Status: Custom Synthesis

Chemical Name: 2-(((3aS,4R,6R,6aR)-6-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 94

CAT No: CL-TGR-265 CAS No: NA Mol Wt: 169.2 : 152.1 Mol F: C9H9F2N : C8H8O3 Inv Status: Custom Synthesis

Chemical Name: (1R,2S)-2-(2,3-difluorophenyl)cyclopropan-1-amine 2-hydroxy-2-phenylacetate

Ticagrelor Related Compound 95

CAT No: CL-TGR-266 CAS No: NA Mol Wt: 570.7 Mol F: C24H38N6O8S Inv Status: Custom Synthesis

Chemical Name: ?(1S,2S,3S)-3-(2-hydroxyethoxy)-5-((3-((3aS,4S,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)cyclopentane-1,2-diol

Ticagrelor Related Compound 96

CAT No: CL-TGR-267 CAS No: 1444301-60-3 Mol Wt: 177.2 Mol F: C7H15NO4? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-amino-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Related Compound 97

CAT No: CL-TGR-268 CAS No: NA Mol Wt: 654.6 Mol F: C27H32F2N6O9S Inv Status: Custom Synthesis

Chemical Name: 6-(((1S,2S,3S,4R)-4-(7-(((1R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,3-dihydroxycyclopentyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

Ticagrelor Related Compound 98

CAT No: CL-TGR-269 CAS No: NA Mol Wt: 562.6 Mol F: C26H32F2N6O4S? Inv Status: Custom Synthesis

Chemical Name: 2-(((3aS,4R,6S,6aR)-6-(7-(((1S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Related Compound 99

CAT No: CL-TGR-270 CAS No: 376608-75-2 Mol Wt: 429.9 Mol F: C17H24ClN5O4S Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4S,6R,6aS)-6-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Sulfonate Impurity

CAT No: CL-TGR-271 CAS No: NA Mol Wt: 602.6 Mol F: C23H28F2N6O7S2 Inv Status: Custom Synthesis

Chemical Name: 2-(((1S,2S,3S,4R)-4-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,3-dihydroxycyclopentyl)oxy)ethyl hydrogen sulfate

Ticagrelor Impurity L (Mixture of Diastereomers)

CAT No: CL-TGR-272 CAS No: NA Mol Wt: 538.6 Mol F: C23H28F2N6O5S? Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylsulfinyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 186

CAT No: CL-TGR-273 CAS No: 151527-83-2 Mol Wt: 173.2 Mol F: C8H15NO3 Inv Status: Custom Synthesis

Chemical Name: (3aR,4R,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Impurity 188

CAT No: CL-TGR-274 CAS No: 2271293-30-0 Mol Wt: 520.6 Mol F: C23H26F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(5-(allylthio)-7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 190

CAT No: CL-TGR-275 CAS No: 2378409-03-9 Mol Wt: 620.6 Mol F: C24H35Cl2N7O4S2 Inv Status: Custom Synthesis

Chemical Name: N4-((3aS,4R,6S,6aR)-6-(2-((5-Amino-6-chloro-2-(propylthio)pyrimidin-4-yl)oxy)ethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)-6-chloro-2-(propylthio)pyrimidine-4,5-diamine

Ticagrelor Impurity 191

CAT No: CL-TGR-276 CAS No: 2376278-67-8 Mol Wt: 217.3 Mol F: C10H19NO4 Inv Status: Custom Synthesis

Chemical Name: 2-(((3aR,4R,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 192

CAT No: CL-TGR-277 CAS No: 2714888-22-7 Mol Wt: 524.6 Mol F: C23H30F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-Amino-5-(propylthio)-1,2-dihydro-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-(2-(3,4-difluorophenyl)cyclopropoxy)ethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 196

CAT No: CL-TGR-278 CAS No: 1882095-50-2 Mol Wt: 629.7 Mol F: C27H43N5O10S Inv Status: Custom Synthesis

Chemical Name: 2,2'-(((3aR,3a'R,4S,4'S,6R,6aS,6'R,6a'S)-((5-nitro-2-(propylthio)pyrimidine-4,6-diyl)bis(azanediyl))bis(2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxole-6,4-diyl))bis(oxy))bis(ethan-1-ol)

Deshydroxyethoxy Ticagrelor-D7

CAT No: CL-TGR-279 CAS No: NA Mol Wt: 485.6 Mol F: C21H17D7F2N6O3S Inv Status: Custom Synthesis

Chemical Name: (1S,2R,3S,4R)-4-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-((propyl-d7)thio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2,3-triol

Ticagrelor D7

CAT No: CL-TGR-280 CAS No: 1265911-55-4 Mol Wt: 529.6 Mol F: C23H21D7F2N6O4S Inv Status: Custom Synthesis

Chemical Name: (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-((propyl-d7)thio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 128

CAT No: CL-TGR-281 CAS No: 1416158-39-8 Mol Wt: 287.4 Mol F: C14H25NO5 Inv Status: Custom Synthesis

Chemical Name: Tert-butyl 2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate

Ticagrelor Impurity 129

CAT No: CL-TGR-282 CAS No: 2382303-05-9 Mol Wt: 169.2 Mol F: C9H9F2N Inv Status: Custom Synthesis

Chemical Name: (1R,2R)-2-(2,3-Difluorophenyl)cyclopropan-1-amine

Type:Impurity Reference Standard

API NAME:Ticagrelor

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