Impurity Reference Standard - Products

Timolol Maleate

CAT No: CL-TMOL-01 CAS No: 26921-17-5 Mol Wt: 316.4 : 116.1 Mol F: C13H24N4O3S : C4H4O4 Inv Status: Custom Synthesis

Chemical Name: (S)-1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol maleate

Timolol EP Impurity A

CAT No: CL-TMOL-02 CAS No: 26839-76-9 Mol Wt: 316.4 Mol F: C13H24N4O3S Inv Status: Custom Synthesis

Chemical Name: (2R)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol ; (R)-1-(tert-Butylamino)-3-(4-morpholino-1,2,5-thiadiazol-3-yloxy)propan-2-ol (as per USP)

Timolol EP Impurity B

CAT No: CL-TMOL-03 CAS No: 59697-06-2 Mol Wt: 316.4 Mol F: C13H24N4O3S Inv Status: Custom Synthesis

Chemical Name: (2RS)-3-[(1,1-dimethylethyl)amino]-2-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-1-ol ; 3-(tert-Butylamino)-2-(4-morpholino-1,2,5-thiadiazol-3-yloxy)propan-1-ol (as per USP)

Timolol EP Impurity C

CAT No: CL-TMOL-04 CAS No: 610271-56-2 Mol Wt: 485.6 Mol F: C19H31N7O4S2 Inv Status: Custom Synthesis

Chemical Name: (2RS)-N-(1,1-dimethylethyl)-2,3-bis[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-1-amine

Timolol EP Impurity D

CAT No: CL-TMOL-05 CAS No: 30165-97-0 Mol Wt: 187.2 Mol F: C6H9N3O2S Inv Status: Custom Synthesis

Chemical Name: 4-(Morpholin-4-yl)-1,2,5-thiadiazol-3-ol ; 4-Morpholino-1,2,5-thiadiazol-3-ol (as per USP)

Timolol EP Impurity E

CAT No: CL-TMOL-06 CAS No: 1026075-53-5 Mol Wt: 414.5 Mol F: C17H26N4O6S Inv Status: Custom Synthesis

Chemical Name: (2Z)-4-[(1S)-1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]ethoxy]-4-oxobut-2-enoic acid ; (S,Z)-4-({1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl}oxy)-4-oxobut-2- enoic acid (as per USP)

Timolol EP Impurity F

CAT No: CL-TMOL-07 CAS No: 30165-96-9 Mol Wt: 205.7 Mol F: C6H8ClN3OS Inv Status: Custom Synthesis

Chemical Name: 4-(4-Chloro-1,2,5-thiadiazol-3-yl)morpholine ; 3-Chloro-4-morpholino-1,2,5-thiadiazol (as per USP)

Timolol EP Impurity G

CAT No: CL-TMOL-08 CAS No: 79844-78-3 Mol Wt: 241.31 Mol F: C6H8KN3O3S Inv Status: Custom Synthesis

Chemical Name: 4-(4-Morpholinyl)-1,2,5-Thiadiazol-3(2H)-one 1-Oxide Potassium Salt

Timolol EP Impurity H

CAT No: CL-TMOL-09 CAS No: 158636-97-6 Mol Wt: 316.4 Mol F: C13H24N4O3S Inv Status: Custom Synthesis

Chemical Name: 2-[(2RS)-3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl]-4-(morpholin-4-yl)-1,2,5-thiadiazol-3(2H)-one

Timolol EP Impurity I

CAT No: CL-TMOL-10 CAS No: 2469037-77-0 Mol Wt: 288.4 Mol F: C11H20N4O3S Inv Status: In Stock

Chemical Name: (2RS)-1-(ethylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol

Timolol EP Impurity J

CAT No: CL-TMOL-11 CAS No: NA Mol Wt: 376.5 Mol F: C16H32N4O4S Inv Status: Custom Synthesis

Chemical Name: 1,1'-[1,2,5-Thiadiazol-3,4-diylbis(oxy)]bis[3-[(1,1-dimethylethyl)amino]propan-2-ol]

Hydroxy Timolol

CAT No: CL-TMOL-12 CAS No: 57519-98-9 Mol Wt: 332.4 Mol F: C13H24N4O4S Inv Status: Custom Synthesis

Chemical Name: 2-((2-hydroxy-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propyl)amino)-2-methylpropan-1-ol

Timolol Impurity 1

CAT No: CL-TMOL-13 CAS No: 75014-25-4 Mol Wt: 348.4 Mol F: C13H24N4O5S Inv Status: Custom Synthesis

Chemical Name: (S)-N-(4-(3-(tert-butylamino)-2-hydroxypropoxy)-1,2,5-thiadiazol-3-yl)-N-(2-hydroxyethyl)glycine

Timolol Impurity 2

CAT No: CL-TMOL-14 CAS No: 75014-26-5 Mol Wt: 290.4 Mol F: C11H22N4O3S Inv Status: Custom Synthesis

Chemical Name: (S)-1-(tert-butylamino)-3-((4-((2-hydroxyethyl)amino)-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol

Timolol Impurity 3

CAT No: CL-TMOL-15 CAS No: 75045-22-6 Mol Wt: 275.3 Mol F: C9H13N3O5S Inv Status: Custom Synthesis

Chemical Name: (R)-2-hydroxy-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propanoic acid

Timolol EP Impurity A (Maleate salt)

CAT No: CL-TMOL-16 CAS No: 26839-77-0 ; 26839-76-9 (free base) Mol Wt: 316.4 : 116.1 Mol F: C13H24N4O3S : C4H4O4 Inv Status: In Stock

Chemical Name: (2R)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol maleate

Timolol USP Related Compound C

CAT No: CL-TMOL-17 CAS No: 610271-57-3 ; 610271-56-2 (free base) Mol Wt: 485.6 : 116.1 Mol F: C19H31N7O4S2 : C4H4O4 Inv Status: In Stock

Chemical Name: N-(Tert-butyl)-2,3-bis((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-1-amine maleate

Timolol EP Impurity G (free base)

CAT No: CL-TMOL-18 CAS No: 75202-36-7 ; 79844-78-3 (K salt) Mol Wt: 203.2 Mol F: C6H9N3O3S Inv Status: In Stock

Chemical Name: 3-Hydroxy-4-morpholino-1,2,5-thiadiazole 1-oxide

(S)-Isotimolol

CAT No: CL-TMOL-19 CAS No: 158636-96-5 Mol Wt: 316.4 Mol F: C13H24N4O3S Inv Status: Custom Synthesis

Chemical Name: (S)-3-(tert-butylamino)-2-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-1-ol

Timolol Impurity 4

CAT No: CL-TMOL-20 CAS No: 610271-58-4 Mol Wt: 256.3 Mol F: C10H16N4O2S Inv Status: Custom Synthesis

Chemical Name: 3,4-Dimorpholino-1,2,5-thiadizaole

Timolol Impurity K

CAT No: CL-TMOL-21 CAS No: 69500-53-4 Mol Wt: 243.3 Mol F: C9H13N3O3S Inv Status: Custom Synthesis

Chemical Name: (S)-4-(4-(oxiran-2-ylmethoxy)-1,2,5-thiadiazol-3-yl)morpholine

rac Timolol Maleate

CAT No: CL-TMOL-22 CAS No: 57073-55-9 Mol Wt: 316.4 : 116.1 Mol F: C13H24N4O3S : C4H4O4 Inv Status: Custom Synthesis

Chemical Name: 1-(Tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol maleate

Timolol Impurity 5

CAT No: CL-TMOL-23 CAS No: 1391068-18-0 Mol Wt: 485.6 Mol F: C19H31N7O4S2 Inv Status: Custom Synthesis

Chemical Name: (S)-N-(tert-butyl)-2,3-bis((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-1-amine

Timolol EP Impurity E (Maleate salt)

CAT No: CL-TMOL-24 CAS No: NA Mol Wt: 414.5 : 116.1 Mol F: C17H26N4O6S : C4H4O4 Inv Status: Custom Synthesis

Chemical Name: (2Z)-4-[(1S)-1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]ethoxy]-4-oxobut-2-enoic acid, maleic acid (1:1)

Timolol EP Impurity B (Maleate salt)

CAT No: CL-TMOL-25 CAS No: 610271-55-1 Mol Wt: 316.4 : 116.1 Mol F: C13H24N4O3S : C4H4O4 Inv Status: Custom Synthesis

Chemical Name: 3-(Tert-butylamino)-2-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-1-ol maleate

Timolol

CAT No: CL-TMOL-26 CAS No: 26839-75-8 Mol Wt: 316.4 Mol F: C13H24N4O3S Inv Status: Custom Synthesis

Chemical Name: (S)-1-(Tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol

Timolol Impurity 6

CAT No: CL-TMOL-27 CAS No: 158636-99-8 Mol Wt: 243.3 Mol F: C10H17N3O2S Inv Status: Custom Synthesis

Chemical Name: 4-(4-(Tert-butoxy)-1,2,5-thiadiazol-3-yl)morpholine

Timolol Impurity 7

CAT No: CL-TMOL-28 CAS No: 30315-49-2 Mol Wt: 235.3 Mol F: C14H21NO2 Inv Status: Custom Synthesis

Chemical Name: (3-(Tert-butyl)-2-phenyloxazolidin-5-yl)methanol

Timolol Impurity 8

CAT No: CL-TMOL-29 CAS No: 2983462-63-9 Mol Wt: 404.5 Mol F: C20H28N4O3S Inv Status: Custom Synthesis

Chemical Name: 4-(4-(((5S)-3-(Tert-butyl)-2-phenyloxazolidin-5-yl)methoxy)-1,2,5-thiadiazol-3-yl)morpholine

Timolol Dimer

CAT No: CL-TMOL-30 CAS No: NA Mol Wt: 559.7 Mol F: C22H37N7O6S2 Inv Status: Custom Synthesis

Chemical Name: (2S,2'S)-3,3'-(tert-butylazanediyl)bis(1-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol)

Timolol Oxazolidinyl Benzenesulfonate

CAT No: CL-TMOL-32 CAS No: 345585-14-0 Mol Wt: 375.5 Mol F: C20H25NO4S Inv Status: Custom Synthesis

Chemical Name: (3-(Tert-butyl)-2-phenyloxazolidin-5-yl)methyl benzenesulfonate

Timolol Impurity 9

CAT No: CL-TMOL-33 CAS No: 30315-46-9 Mol Wt: 147.2 Mol F: C7H17NO2 Inv Status: Custom Synthesis

Chemical Name: (S)-3-(Tert-butylamino)propane-1,2-diol

Timolol-D5

CAT No: CL-TMOL-34 CAS No: NA Mol Wt: 321.5 Mol F: C13H19D5N4O3S Inv Status: Custom Synthesis

Chemical Name: 1-(Tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-1,1,2,3,3-d5-2-ol

Type:Impurity Reference Standard

API NAME:Timolol

Total Products: 33

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