Impurity Reference Standard - Products

Zanubrutinib

CAT No: CL-ZNBT-01 CAS No: 1691249-45-2 Mol Wt: 471.6 Mol F: C27H29N5O3 Inv Status: Custom Synthesis

Chemical Name: (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Zanubrutinib Impurity 1

CAT No: CL-ZNBT-02 CAS No: 1633352-71-2 Mol Wt: 417.5 Mol F: C24H27N5O2 Inv Status: Custom Synthesis

Chemical Name: (S)-2-(4-Phenoxyphenyl)-7-(piperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Zanubrutinib Impurity 2

CAT No: CL-ZNBT-03 CAS No: 1633351-79-7 Mol Wt: 508 Mol F: C27H30ClN5O3 Inv Status: Custom Synthesis

Chemical Name: (S)-7-(1-(3-Chloropropanoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Zanubrutinib Impurity 3

CAT No: CL-ZNBT-04 CAS No: 2432022-47-2 Mol Wt: 453.5 Mol F: C27H27N5O2 Inv Status: Custom Synthesis

Chemical Name: (S)-7-(1-Acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbonitrile

Zanubrutinib Impurity 4

CAT No: CL-ZNBT-05 CAS No: 1691249-44-1 Mol Wt: 471.55 Mol F: C27H29N5O3 Inv Status: Custom Synthesis

Chemical Name: (R)-7-(1-acryloyl piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydro pyrazolo [1,5-a]pyrimidine-3-carboxamide

Zanubrutinib Impurity 5

CAT No: CL-ZNBT-06 CAS No: NA Mol Wt: 889.1 Mol F: C51H56N10O5 Inv Status: Custom Synthesis

Chemical Name: (7S,7'S)-7,7'-((1-oxopropane-1,3-diyl)bis(piperidine-1,4-diyl))bis(2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide)

Zanubrutinib Impurity 6

CAT No: CL-ZNBT-07 CAS No: NA Mol Wt: 495.6 Mol F: C25H29N5O4S Inv Status: Custom Synthesis

Chemical Name: (S)-7-(1-(Methylsulfonyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Zanubrutinib Impurity 7

CAT No: CL-ZNBT-08 CAS No: NA Mol Wt: 487.6 Mol F: C27H29N5O4 Inv Status: Custom Synthesis

Chemical Name: (S)-7-(1-Acryloylpiperidin-4-yl)-3-carbamoyl-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine 1-oxide

Zanubrutinib Impurity 8

CAT No: CL-ZNBT-09 CAS No: NA Mol Wt: 795.8 Mol F: C39H49N5O13 Inv Status: Custom Synthesis

Chemical Name: (7S)-7-(1-Acryloylpiperidin-4-yl)-4-((3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Zanubrutinib Impurity 9

CAT No: CL-ZNBT-10 CAS No: NA Mol Wt: 795.8 Mol F: C39H49N5O13 Inv Status: Custom Synthesis

Chemical Name: (S)-7-(1-Acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4-((3S,4R,5R)-3,5,6-trihydroxy-2-oxo-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Zanubrutinib Impurity 13

CAT No: CL-ZNBT-11 CAS No: NA Mol Wt: 373.5 Mol F: C24H27N3O Inv Status: Custom Synthesis

Chemical Name: (7S)-2-(4-phenoxyphenyl)-7-(piperidin-4-yl)-5,6,7,7a-tetrahydro-4H-pyrrolo[3,2-b]pyridine

Zanubrutinib Impurity 14

CAT No: CL-ZNBT-12 CAS No: NA Mol Wt: 488.6 Mol F: C28H32N4O4 Inv Status: Custom Synthesis

Chemical Name: 3-(4-((7S)-3-carbamoyl-2-(4-phenoxyphenyl)-5,6,7,7a-tetrahydro-4H-pyrrolo[3,2-b]pyridin-7-yl)piperidin-1-yl)propanoic acid

Zanubrutinib Impurity 15

CAT No: CL-ZNBT-13 CAS No: NA Mol Wt: 488.6 Mol F: C28H32N4O4 Inv Status: Custom Synthesis

Chemical Name: 3-((7S)-3-carbamoyl-2-(4-phenoxyphenyl)-7-(piperidin-4-yl)-5,6,7,7a-tetrahydro-4H-pyrrolo[3,2-b]pyridin-4-yl)propanoic acid

Zanubrutinib Impurity 10

CAT No: CL-ZNBT-14 CAS No: 330792-70-6 Mol Wt: 276.3 Mol F: C16H12N4O Inv Status: Custom Synthesis

Chemical Name: 5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

Zanubrutinib Impurity 11

CAT No: CLZ-ZNBT-15 CAS No: 1799799-87-3 Mol Wt: 282.4 Mol F: C15H26N2O3 Inv Status: Custom Synthesis

Chemical Name: Tert-butyl (E)-4-(3-(dimethylamino)acryloyl)piperidine-1-carboxylate

Zanubrutinib R-isomer

CAT No: CL-ZNBT-16 CAS No: 1691249-44-1 Mol Wt: 471.6 Mol F: C27H29N5O3 Inv Status: Custom Synthesis

Chemical Name: (R)-7-(1-Acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Zanubrutinib 4-Acryloyl Impurity

CAT No: CL-ZNBT-17 CAS No: NA Mol Wt: 471.6 Mol F: C27H29N5O3 Inv Status: Custom Synthesis

Chemical Name: (S)-4-Acryloyl-2-(4-phenoxyphenyl)-7-(piperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Zanubrutinib Amino Acid Impurity

CAT No: CL-ZNBT-18 CAS No: NA Mol Wt: 489.6 Mol F: C27H31N5O4 Inv Status: Custom Synthesis

Chemical Name: 3-(4-(3-Carbamoyl-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl)propanoic acid

Zanubrutinib Di Acryloyl Impurity

CAT No: CL-ZNBT-19 CAS No: NA Mol Wt: 525.6 Mol F: C30H31N5O4 Inv Status: Custom Synthesis

Chemical Name: (S)-4-Acryloyl-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Zanubrutinib Impurity 12

CAT No: CL-ZNBT-20 CAS No: NA Mol Wt: 941.1 Mol F: C56H60N8O6 Inv Status: Custom Synthesis

Chemical Name: (7S)-7-(1-acryloylpiperidin-4-yl)-4-(3-(4-((7S)-3-carbamoyl-2-(4-phenoxyphenyl)-5,6,7,7a-tetrahydro-4H-pyrrolo[3,2-b]pyridin-7-yl)piperidin-1-yl)-3-oxopropyl)-2-(4-phenoxyphenyl)-5,6,7,7a-tetrahydro-4H-pyrrolo[3,2-b]pyridine-3-carboxamide

Type:Impurity Reference Standard

API NAME:Zanubrutinib

Total Products: 20

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